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Novel Influenza A Virus Infections
One human infection with influenza A(H1N2) variant (A(H1N2)v) virus was reported by the Iowa Department of Health and Human Services.
The patient is ≥18 years of age and sought health care during the week ending January 18, 2025 (Week 3), was hospitalized, and has recovered from their illness.
An investigation by state public health officials did not identify direct or indirect swine contact by the patent.
No illness was identified among the patient's close contacts.
No human-to-human transmission has been identified associated with this case.
This is the first human infection with a variant influenza virus reported during the 2024-2025 season in the United States.
When an influenza virus that normally circulates in swine (but not people) is detected in a person, it is called a "variant" influenza virus.
Most human infections with variant influenza viruses occur following exposure to swine, but human-to-human transmission can occur.
It is important to note that in most cases, variant influenza viruses have not shown the ability to spread easily and sustainably from person to person.
Additional information on influenza in swine, variant influenza virus infection in humans, and guidance to interact safely with swine can be found at www.cdc.gov/flu/swineflu/index.htm.
No new human infections with A(H5) were reported to CDC this week. An ongoing outbreak of H5N1 continues in domestic dairy cows and poultry, and monitoring for additional human cases is ongoing.
The CSTE position statement, which includes updated case definitions for confirmed, probable, and suspected cases is available at http://www.cste.org/resource/resmgr/position_statements_files_2023/24-ID-09_Novel_Influenza_A.pdf
An up-to-date human A(H5) case summary during the outbreak by state and exposure source is available at www.cdc.gov/bird-flu/situation-summary/index.html
Information about avian influenza is available at https://www.cdc.gov/flu/avianflu/index.htm.
Interim recommendations for Prevention, Monitoring, and Public Health Investigations are available at https://www.cdc.gov/bird-flu/prevention/hpai-interim-recommendations.html.
The latest case reports on avian influenza outbreaks in wild birds, commercial poultry, backyard or hobbyist flocks, and mammals in the United States are available from the USDA at https://www.aphis.usda.gov/aphis/ourfocus/animalhealth/animal-disease-information/avian/avian-influenza/2022-hpai.
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Source: US Centers for Disease Control and Prevention, https://www.cdc.gov/fluview/surveillance/2025-week-05.html
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