Skip to main content

Posts

Showing posts with the label a/h3n8

#Evidence of avian and human #influenza A virus #infection in farmed Siamese #crocodiles (Crocodylus siamensis) in #Thailand

Abstract Crocodilians are susceptible to a range of virus infection including influenza A virus (IAV). However, little is known about the ecology and epidemiology of IAV in crocodile species. This study aimed to investigate IAV infection in farmed Siamese crocodiles in central Thailand . We collected plasma samples and pharyngeal swab samples from Siamese crocodiles residing in 13 crocodile farms in 9 provinces of central Thailand during 2019. Additional archival plasma samples of Siamese crocodiles collected in 2012 and 2018 were also included in the study. Plasma samples were screened for influenza A antibodies by a hemagglutination inhibition (HI) assay and positive were evaluated by a cytopathic effect/hemagglutination based- microneutralization (MN) assay . Swab samples were tested for influenza viral RNA by a real-time RT-PCR assay targeting the influenza matrix (M) gene. Among 246 tested plasma samples, the overall seroprevalence of antibodies against IAV in farmed Siamese croco...

Evidence of #Influenza A(#H5N1) #Spillover #Infections in #Horses, #Mongolia

Abstract Recent outbreaks of influenza A(H5N1) have affected many mammal species . We report serologic evidence of H5N1 virus infection in horses in Mongolia . Because H3N8 equine influenza virus is endemic in many countries, horses should be monitored to prevent reassortment between equine and avian influenza viruses with unknown consequences. Source: Emerging Infectious Diseases Journal,  https://wwwnc.cdc.gov/eid/article/31/1/24-1266_article _____

Prior #infection with IBDV prolonged the shedding of a #mallard #H3N8 #influenza A virus (IAV) challenge from oropharyngeal cavity of some #chickens {...}

Abstract Infectious bursal disease virus (IBDV) is endemic worldwide and causes immunosuppression in chickens . We hypothesized that a previous history of IBDV in chickens would render them more susceptible to infection by influenza A viruses (IAVs) from aquatic waterfowl reservoirs . To model this, we inoculated 14 day old specific pathogen free (SPF) chickens with a low pathogenicity avian influenza (LPAI) virus strain from a mallard ( A/Mallard/Alberta/156/01 (H3N8) ) and compared replication and shedding between immunocompetent chickens and chickens that had immune dysregulation due to a prior IBDV infection with strain F52/70 (genogroup A1B1) at 2 days of age. The mallard IAV strain replicated in the upper respiratory tract of the chickens , and virus was shed from the oropharyngeal cavity , but there was no shedding from the cloaca , and no transmission to sentinel chickens . Replication of the mallard IAV in the chicken host was associated with amino acid substitutions in the po...