ETIDIOH - NEW: pandemic influenza

Showing posts with label pandemic influenza. Show all posts

Saturday, October 3, 2026

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, Oct. 3 '23)

Antiviral Res

MA S, Chen Y, Zhu J, Zong Y, et al
N70S/Y155H Combined Mutation of Neuraminidase of Avian Influenza H9N2 Virus confers oseltamivir and zanamivir resistance and pathogenicity to Mice.
Antiviral Res. 2026 Sep 29:106540. doi: 10.1016/j.antiviral.2026.106540.
PubMed Abstract available

J Infect

NAZARETH J, Martin CA, Pan D, Barr IG, et al
Ethnic differences in inactivated influenza vaccine immunogenicity in UK Healthcare Workers: A two-year prospective longitudinal study.
J Infect. 2026 Sep 29:106862. doi: 10.1016/j.jinf.2026.106862.
PubMed Abstract available

DUAN Q, Jin X, Fu X, Zhu A, et al
Household transmission dynamics of human respiratory syncytial virus in China: A multicentre epidemiological and molecular study.
J Infect. 2026;93:106834.
PubMed Abstract available

ZHOU S, Liu C, Liu W, Cai K, et al
Cross-Neutralizing Antibody Responses to Diverse Coronaviruses in the Human Population.
J Infect. 2026 Aug 11:106827. doi: 10.1016/j.jinf.2026.106827.
PubMed Abstract available

LI X, Mercade-Besora N, Lam AS, Barboza C, et al
Effectiveness and waning of the fourth dose mRNA COVID-19 vaccines for the prevention of SARS-CoV2 infection related hospitalisations and deaths.
J Infect. 2026 Aug 5:106825. doi: 10.1016/j.jinf.2026.106825.
PubMed Abstract available

QUINOT C, Lunt R, Kirsebom F, Andrews N, et al
Serological outcomes of SARS-CoV-2 infection by vaccination status and variant in England.
J Infect. 2026;93:106819.
PubMed Abstract available

MMWR Morb Mortal Wkly Rep

KYAW NTT, Foote MMK, Lo Piccolo AJ, Wallach AB, et al
Unannounced Drills Using Patient Actors to Evaluate Health Care Facility Readiness for Infectious Disease Outbreaks - New Jersey, New York, and U.S. Virgin Islands, January-June 2026.
MMWR Morb Mortal Wkly Rep. 2026;75:581-587.
PubMed Abstract available

Pediatrics

FRINTNER MP, Freed GL, Byrne BJ, Gottschlich EA, et al
Pediatrician Burnout Over Time: 2021-2025.
Pediatrics. 2026;158:e2026076643.
PubMed Abstract available

PLoS Biol

DAILEY KE, Wang Y, Teo QW, Wang C, et al
Epistasis and pleiotropy constrain the evolution of cross-reactive breadth in a broadly neutralizing influenza antibody.
PLoS Biol. 2026;24:e3004021.
PubMed Abstract available

PLoS Comput Biol

LEMAITRE J, Lessler J
Generative diffusion models for spatiotemporal influenza forecasting.
PLoS Comput Biol. 2026;22:e1014846.
PubMed Abstract available

PLoS One

LI Q, Bond RM, Nisbet E, Dixon G, et al
The limited effects of social media use on misperceptions Social media's limited role in misperceptions.
PLoS One. 2026;21:e0354486.
PubMed Abstract available

RICO-BOLIVAR DL, Diaz-Brochero C, Hattemer R, Bejarano-Mora CA, et al
Causes of hospitalization among people living with HIV in a tertiary-care hospital in Bogota, Colombia, 2018-2024.
PLoS One. 2026;21:e0357788.
PubMed Abstract available

DUCHOWNY K, Wang V, Noppert G, Melendez R, et al
Essential work, unequal places: Neighborhood characteristics of the essential workforce in the United States during the COVID-19 pandemic.
PLoS One. 2026;21:e0357792.
PubMed Abstract available

DE ANDA-JAUREGUI G, Sifuentes-Osornio J, Angulo-Guerrero O, Diaz-De-Leon-Santiago JL, et al
Complexity of hospital demand during the COVID-19 pandemic in Mexico City.
PLoS One. 2026;21:e0358798.
PubMed Abstract available

NEVES RKAD, Bastos LS, Maciel Villela DA, Saraceni V, et al
Rehospitalization due to COVID-19 reinfection in Rio de Janeiro, 2020-2022: Associations with vaccination status, sociodemographic and clinical factors.
PLoS One. 2026;21:e0332281.
PubMed Abstract available

BABAZADEH SHAREH M, Kleiner F, Bohme M, Hagele C, et al
Automated model discovery based on COVID-19 epidemiological data from Thuringia, Germany.
PLoS One. 2026;21:e0344409.
PubMed Abstract available

ONYANGO EO, Kiplagat J, Gokiert R, Owuor PM, et al
An intersectionality-based policy analysis of COVID-19 measures and women informal food vendors in Kisumu, Kenya.
PLoS One. 2026;21:e0359620.
PubMed Abstract available

MESQUITA S, Loureiro J, Haupt Vieira C, Perfeito L, et al
Learning from pandemics: Feature selection and clustering for robust digital disease nowcasting.
PLoS One. 2026;21:e0358063.
PubMed Abstract available

ABI ZEID B, El Khoury T, Abdulrahim S, Ghattas H, et al
Predicting COVID-19 infection among older Syrian refugees in Lebanon: A multi-wave survey.
PLoS One. 2026;21:e0359272.
PubMed Abstract available

BOZDECH M
Rising performance-efficiency demands in female junior tennis: A longitudinal analysis of ITF World Tennis Tour Juniors rankings, 2004-2025.
PLoS One. 2026;21:e0359538.
PubMed Abstract available

JOHNSON G, Edwards S, Jarman H, Peel E, et al
Understanding delivery of bad news in the emergency department: A scoping review.
PLoS One. 2026;21:e0358343.
PubMed Abstract available

Proc Natl Acad Sci U S A

DUDLEY C, Magdaleno R, Harding C, Sharma A, et al
Mantis: A foundation model for mechanistic disease forecasting.
Proc Natl Acad Sci U S A. 2026;123:e2602542123.
PubMed Abstract available

Vaccine

NIAN H, Ding T, Lee RL, Gebretsadik T, et al
COVID-19 vaccine uptake among individuals with Down syndrome in the Unites States.
Vaccine. 2026;92:129128.
PubMed Abstract available

OKHOLM AK, Fougeroux C, Hagen SH, Paludan SR, et al
Virus-like particle display of the SARS-CoV-2 receptor-binding domain using a modular tag/catcher system enhances immunogenicity of a DNA vaccine in mice.
Vaccine. 2026;92:129117.
PubMed Abstract available

C M, Dymock M, Flanagan KL, Plebanski M, et al
The platform trial in COVID-19 priming and BOOsting (PICOBOO): The reactogenicity of nine licensed COVID-19 vaccines delivered in immunocompetent adults.
Vaccine. 2026;92:129034.
PubMed Abstract available

ONISHI S, Suzuki Y, Sugimoto K, Otsuka A, et al
Improving intradermal dosing consistency in mice using a hollow microneedle: A model study with a SARS-CoV-2 mRNA vaccine.
Vaccine. 2026;92:129111.
PubMed Abstract available

ALMEIDA MG, Alves de Oliveira BF, de Melo Junior EB, de Araujo Rodrigues AR, et al
Knowledge as a predictor of parental vaccine hesitancy during children's first year of life.
Vaccine. 2026;92:129127.
PubMed Abstract available

DESAI M, Cardona J, Khetan S, Mehta S, et al
Safety and immunogenicity of mRNA-1345 revaccination at least 12 months following primary vaccination with a licensed protein subunit RSV vaccine.
Vaccine. 2026;92:129068.
PubMed Abstract available

BLANCHARD C, Myers J, McNabb AL, Lee YA, et al
Evaluating access to COVID-19 vaccines for children and adolescents in North Carolina through community pharmacies, 2021-2023.
Vaccine. 2026;92:129125.
PubMed Abstract available

FORR A, Salmon DA, Markalanda SH, Joseph A, et al
Promoting a personalized vaccine information website through social media and local outreach: a dissemination and implementation study.
Vaccine. 2026;92:129161.
PubMed Abstract available

HYDER S, Melchinger H, Malik F, Kuppalli K, et al
Trust in government institutions and influenza vaccine acceptance among U.S. adults.
Vaccine. 2026;93:129212.
PubMed Abstract available

TSOU TP, Huang YT, Lin CY, Chu PW, et al
Influenza vaccine effectiveness against influenza-related medical visits, hospitalization and death among adults aged 65 years and older in Taiwan: interim 2024-2025 season result using standard-dose inactivated influenza vaccine.
Vaccine. 2026;93:129165.
PubMed Abstract available

JAYASHANKAR L, DeGrace M, Treanor J, Swanson NJ, et al
Protection Before Day One: advancing broadly protective seasonal influenza vaccines with pandemic coverage.
Vaccine. 2026;93:129188.
PubMed

Giuseppe Michieli

I am an Italian blogger, active since 2005 with main focus on emerging infectious diseases such as avian influenza, SARS, antibiotics resistance, and many other global Health issues. Other fields of interest are: climate change, global warming, geological and biological sciences. My activity consists mainly in collection and analysis of news, public services updates, confronting sources and making decision about what are the 'signals' of an impending crisis (an outbreak, for example). When a signal is detected, I follow traces during the entire course of an event. I started in 2005 my blog ''A TIME'S MEMORY'', now with more than 40,000 posts and 3 millions of web interactions. Subsequently I added an Italian Language blog, then discontinued because of very low traffic and interest. I contributed for seven years to a public forum (FluTrackers.com) in the midst of the Ebola epidemic in West Africa in 2014, I left the site to continue alone my data tracking job.

Saturday, September 26, 2026

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, September 26 '26)

Arch Virol

LEE K, An SH, Heo GB, Lee YJ, et al
Correction: Genomic characterization of H6N1 avian influenza viruses from wild birds and domestic ducks in the republic of Korea and Mongolia (2022-2024).
Arch Virol. 2026;171:283.
PubMed

Biochem Soc Trans

CAWTHORNE W, Zhang Y, Val N, Nelson M, et al
Unmasking programmed cell death in rhinovirus-driven asthma pathology.
Biochem Soc Trans. 2026;54:1359-1373.
PubMed Abstract available

BMC Pediatr

SU L, Chen HS, Qiu WL, Zhong WM, et al
The rationality of drug treatment and clinical characteristics in children with SARS-CoV-2 infection: a retrospective analysis.
BMC Pediatr. 2026;26:894.
PubMed Abstract available

Epidemiol Infect

MITCHELL E, Zhu H, Fitzpatrick T, Majoe A, et al
Social disparities and the COVID-19, influenza, and RSV 'tripledemic' in Ontario, Canada: A population-based study.
Epidemiol Infect. 2026;154:e117.
PubMed Abstract available

Eur J Epidemiol

ANDREASSON J, Bennet L, Bjork J, Dietler D, et al
SARS-CoV-2 infection as a trigger of type 2 diabetes in adults: a population-based cohort study in Sweden using a double negative control design.
Eur J Epidemiol. 2026;41:959-967.
PubMed Abstract available

HELLE S, Tanskanen AO, Danielsbacka M
The decade of double-trouble: live birth and stillbirth sex ratio variation in Finland during the COVID-19 pandemic and Russia's attack on Ukraine.
Eur J Epidemiol. 2026;41:1019-1028.
PubMed Abstract available

J Infect Dis

SCHUMER C, Mann AJ, Fourati S, Lukas P, et al
Viral Dynamics of the Respiratory Syncytial Virus During Experimental Human Challenge: Implication for Transmission and Protection.
J Infect Dis. 2026;234:407-416.
PubMed Abstract available

ALKARKOUKLY S, Hambo S, Menk M, Spieth P, et al
Regulatory T-Cell Notch4 Expression Correlates With Mortality in Patients Hospitalized With COVID-19.
J Infect Dis. 2026;234:396-406.
PubMed Abstract available

ENGELMANN I, Pisoni A, Mille C, Ayadi M, et al
Age-Dependent Clinical and Molecular Rhinovirus Epidemiology, 2018-2023.
J Infect Dis. 2026;234:417-426.
PubMed Abstract available

MCCULLOCH DJ, Khawaja F, Tverdek FP, Ford ES, et al
First Report on Remdesivir Use for the Treatment of Respiratory Syncytial Virus in Five Allogeneic Hematopoietic Cell Transplant Recipients.
J Infect Dis. 2026;234:e552-e555.
PubMed Abstract available

MARCHAL A, Kerdiles T, Perrin A, Gervais A, et al
High Nasopharyngeal SARS-CoV-2 Load and Delayed Clearance in Hospitalized Patients With Blood Autoantibodies Neutralizing Type I Interferons.
J Infect Dis. 2026;234:e515-e521.
PubMed Abstract available

ROEN AO, Hedberg P, Pereira JPV, Zazzi M, et al
Increased In-Hospital Mortality in Immunocompromised Individuals Hospitalized With COVID-19 During the Global Pandemic: A Multinational Cohort Study in the EuCARE Project.
J Infect Dis. 2026;234:e496-e505.
PubMed Abstract available

FREYN AW, Budigi Y, Girard B, Santos G, et al
Cell-Mediated Immunity of mRNA-1283 Vaccine Encoding SARS-CoV-2 Spike Receptor-Binding and N-Terminal Domains in Preclinical and Clinical Studies.
J Infect Dis. 2026 Jun 4:jiag248. doi: 10.1093.
PubMed Abstract available

J Virol

ZHANG L, Chen N, Eichmann A, Nehlmeier I, et al
The conserved QTQTX motif in the SARS-CoV-2 spike protein is dispensable for cleavage and lung cell entry of the emerging variant BA.3.2.
J Virol. 2026 Aug 5:e0069126. doi: 10.1128/jvi.00691.
PubMed Abstract available

RIOS CARRASCO M, Guerreiro Cabana MF, Kovacs E, Ducarne Z, et al
Acquisition of specific human respiratory tract binding by 2.3.4.4b H5N1 hemagglutinins requires multiple mutations.
J Virol. 2026;100:e0106526.
PubMed Abstract available

KUMAR S, Lai L, Ellis ML, Patel A, et al
Immunological imprinting shapes the cross-reactive antibody responses to the KP.2 and LP.8.1 vaccine doses.
J Virol. 2026 Aug 26:e0074926. doi: 10.1128/jvi.00749.
PubMed Abstract available

STADLER E, Mordant F, Gartner M, Docken SS, et al
Reconciliation of titer differences between SARS-CoV-2 neutralizing antibody assays.
J Virol. 2026 Aug 27:e0082326. doi: 10.1128/jvi.00823.
PubMed Abstract available

LIU G, Chen J, Wu F, Wei P, et al
Nanobodies targeting SARS-CoV-2 papain-like protease exert dual antiviral and anti-inflammatory effects.
J Virol. 2026 Aug 28:e0059926. doi: 10.1128/jvi.00599.
PubMed Abstract available

XIE E, Schubert M, Reeb J, Seligmann B, et al
Arp2/3 complex-dependent actin remodeling is required for efficient RSV uncoating in A549 cells.
J Virol. 2026;100:e0111726.
PubMed Abstract available

ULLAH R, Chen W, Zhang L, Guo C, et al
Interaction between DEAD-box RNA helicase 10 and influenza PB1 polymerase selectively regulates influenza A virus replication.
J Virol. 2026 Sep 22:e0081526. doi: 10.1128/jvi.00815.
PubMed Abstract available

LEMUS-REYES JI, Fernandez-Quintero ML, Ayala E, Swanson OM, et al
Antigenic and structural analysis of the influenza hemagglutinin lateral patch.
J Virol. 2026 Sep 23:e0126526. doi: 10.1128/jvi.01265.
PubMed Abstract available

PARK H-S, Matsuoka Y, Santos C, Duncan EF, et al
Co-administration of intranasal parainfluenza virus vaccines expressing antigenically distinct SARS-CoV-2 S antigens elicits broad and durable immunity in hamsters.
J Virol. 2026 Sep 24:e0093826. doi: 10.1128/jvi.00938.
PubMed Abstract available

PLoS One

SODERSTROM LINDSTROM H, Norstrom SH, Tang C, Lindberg RH, et al
Occurrence of influenza antivirals and resistance development in influenza A viruses in aquatic environments: A risk assessment.
PLoS One. 2026;21:e0358447.
PubMed Abstract available

OHLSON A, Rehn M, Kuhlmann Berenzon S, Sturegard E, et al
Evaluation of wastewater SARS-CoV-2 surveillance for monitoring COVID-19 trends and early warning in Sweden, 2023-2024.
PLoS One. 2026;21:e0358326.
PubMed Abstract available

VAN KOEVERING K, Hong Y, Kleinberg J
Social tectonics: Rapid organization of online COVID communities.
PLoS One. 2026;21:e0355369.
PubMed Abstract available

VARGA C
Spatiotemporal clustering of highly pathogenic avian influenza (HPAI) H5N1 at the wild waterfowl-poultry interface: Vector-specific spillover risks in the U.S., 2022-2025.
PLoS One. 2026;21:e0345354.
PubMed Abstract available

ZHANG Y, Zhang Y, Zhao C, Xu X, et al
Quantitative assessment of china's policies on the online sale of prescription drugs.
PLoS One. 2026;21:e0358484.
PubMed Abstract available

AICHBERGER MC, Fetz K, Leong S, Kim HS, et al
Discrimination and technology-based disease control.
PLoS One. 2026;21:e0357004.
PubMed Abstract available

FERNANDEZ-PINEDA M, Swift A, Dolbier C, Swanson M, et al
Navigating grief and healthcare: Mixed-methods study on patient experiences of miscarriage during COVID-19.
PLoS One. 2026;21:e0359158.
PubMed Abstract available

BIR C, Widmar NO, Wolf CA, Sheridan T, et al
Societal values versus individual rights with respect to public health related practices during the COVID-19 pandemic in the U.S.
PLoS One. 2026;21:e0358741.
PubMed Abstract available

Proc Natl Acad Sci U S A

MAROUGKA K, Leiva-Rebollo R, Hofma F, van Dijk A, et al
Substitutions affecting the HA-NA-receptor balance preceded the emergence of the pandemic 2009 H1N1 virus.
Proc Natl Acad Sci U S A. 2026;123:e2609870123.
PubMed Abstract available

Vaccine

SCHAFFNER W, Gravenstein S, Kissler S, Cornely OA, et al
Multicomponent vaccination against seasonal influenza and COVID-19: a strategy to address the continued global burden of disease in adults.
Vaccine. 2026;93:129082.
PubMed Abstract available

Virology

ROWE T, Ross TM
Transcriptional decoupling of the epithelial-immune bridge is associated with suboptimal influenza B virus immunogenicity.
Virology. 2026;625:111075.
PubMed Abstract available

Virus Res

WU Q, Wang ZZ, Wang ZM, Wang YH, et al
Development and validation of a broadly cross-reactive polyclonal antibody as capture antibody for pan human beta coronavirus antigen detection.
Virus Res. 2026;372:199786.
PubMed Abstract available

MANEESRIWONGUL W, Deesamer S, Butsing N
Factors influencing Thai parents' COVID-19 vaccine acceptance for their children: Vaccine attitudes, beliefs, and children's past influenza vaccination.
Virus Res. 2026 Sep 20:199805. doi: 10.1016/j.virusres.2026.199805.
PubMed Abstract available

JANG Y, Cha RM, Park MJ, Kim JM, et al
Genetic Diversity of Clade 2.3.4.4b H5Nx High Pathogenicity Avian Influenza Viruses Detected in Korea During the 2025-2026 Winter Season and Pathogenicity of H5N1 and H5N9 Viruses.
Virus Res. 2026 Sep 22:199807. doi: 10.1016/j.virusres.2026.199807.
PubMed Abstract available

Giuseppe Michieli

Monday, September 21, 2026

Limited added #benefit of seasonal #influenza #vaccination before #H5 vaccination in mice and #ferrets challenged with #H5N1

ABSTRACT

Limited A(H5)-specific vaccine supply is expected early in a potential A(H5N1) pandemic, raising the question of whether licensed seasonal influenza vaccines could enhance protection when administered before A(H5) vaccination. We evaluated this strategy in mouse and ferret models using clade 2.3.4.4b A(H5N1) viruses. Seasonal influenza vaccination induced antibodies to seasonal haemagglutinins but did not induce detectable antibodies against A(H5) and did not consistently enhance A(H5)-directed antibody responses after A(H5) vaccination. In lethal challenge studies, seasonal vaccine priming before A(H5) vaccination was associated with improved outcomes compared with A(H5) vaccination alone in one of three mouse experiments, but this effect was not observed in the other two mouse experiments or in ferrets. These findings suggest that seasonal influenza vaccine priming provides limited added benefit to A(H5) vaccine-mediated protection against A(H5N1) under the conditions tested.

Source:

Link: https://doi.org/10.1080/22221751.2026.2731495

____

Giuseppe Michieli

Saturday, September 19, 2026

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, September 19 '26)

Arch Virol

SEO H, Rauf A, Seo SH
Enhanced induction of inflammatory cytokines in human lung cells infected with highly pathogenic recent H5N1/2024 avian influenza virus.
Arch Virol. 2026;171:278.
PubMed Abstract available

BMC Pediatr

MAITITUERSUN Y, Su R, Yang G, Taerken AY, et al
A longitudinal study on differential impacts of the COVID-19 pandemic and normalized prevention and control on overweight and obese adolescents in China.
BMC Pediatr. 2026;26:882.
PubMed Abstract available

O'SHEA TM, McGrath M, Douglas J, Blackwell CK, et al
Child health-related behaviors, social connectedness, and impact of the COVID-19 pandemic on children born preterm in the ECHO Cohort.
BMC Pediatr. 2026 Jul 20. doi: 10.1186/s12887-026-07337.
PubMed Abstract available

Cell

WU Q, Seydlitz LM, Iakimov V, Hsu DJ, et al
Dietary arginine drives codon-dependent MHC class I translation and improves immunity in colon tumorigenesis and respiratory viral infection.
Cell. 2026;189:6012-6023.
PubMed Abstract available

Eur J Epidemiol

KOSTER EAS, Sluiskes MH, Putter H, Rosendaal FR, et al
Dynamics of infection, vaccination and excess mortality during the COVID-19 pandemic among older individuals-a nationwide analysis.
Eur J Epidemiol. 2026;41:869-880.
PubMed Abstract available

LEHNER CT, Anastasova I, Schauberger G, Eberl M, et al
Increasing incidence of type 1 diabetes in children and adolescents from 2012 to 2021 in Germany: trends before and during the COVID-19 pandemic.
Eur J Epidemiol. 2026;41:881-892.
PubMed Abstract available

J Gen Virol

ROSS RA, Walsh SK, Montgomery H, Chen H, et al
Bovine mammary tissues are susceptible to infection by viruses bearing panzootic H5N1 influenza A virus glycoproteins.
J Gen Virol. 2026;107:002338.
PubMed Abstract available

J Infect

HARRIS R, Thirard R, Iftikhar H, Middleditch A, et al
Corrigendum to "Immunogenicity and safety of co-administration of a recombinant shingles vaccine with an mRNA COVID-19 or adjuvanted influenza vaccine: A randomised controlled trial" [J Infect 93 (2026) 106784].
J Infect. 2026;93:106853.
PubMed

PLoS Biol

VALENCA-PEREIRA F, Johnson B, DeGregori J, Rincon M, et al
Does acute inflammation triggered by infection promote cancer progression?
PLoS Biol. 2026;24:e3003962.
PubMed Abstract available

PLoS Comput Biol

D'AVANZO M, Myint AP, Cacciapaglia G, Hohenegger S, et al
From sequences to strategies: Early detection of new SARS-CoV-2 variants via genetic distance to reduce hospitalizations.
PLoS Comput Biol. 2026;22:e1014707.
PubMed Abstract available

PLoS One

YANG SL, Liu MT, Huang HH, Lin SW, et al
Epidemiology of human RSV in Taiwan, 2018-2024.
PLoS One. 2026;21:e0357769.
PubMed Abstract available

WOLSKO C, Marino E
Incorporating public values into public health communications: Effects of value affirmations on intentions to vaccinate and trust in the U.S.
PLoS One. 2026;21:e0356783.
PubMed Abstract available

FUENTES K, Jacobson D, Birze A, Cadel L, et al
Building capacity in health systems with and for caregivers: A photovoice protocol.
PLoS One. 2026;21:e0358550.
PubMed Abstract available

LI Q, Tang Y, Shi Y, Wu Y, et al
Census-based adolescent depression risk assessment: A novel method and reflections.
PLoS One. 2026;21:e0357661.
PubMed Abstract available

VENKATESAN S, White L, Koo HN, Dickerson J, et al
Estimating cumulative incidence from partially missing time series of respiratory viral infections.
PLoS One. 2026;21:e0353681.
PubMed Abstract available

AKTAS N, Ersoy A, Oruc A, Ortac H, et al
Attitudes, perceptions, behaviours, and concerns of patients listed for kidney transplantation during the COVID-19 pandemic.
PLoS One. 2026;21:e0358328.
PubMed Abstract available

AL-MAGABLEH M, Muhaisen AHM, Ateir RM, Abu Eraq SA, et al
Herbal or conventional medicine? A cross-sectional study of Jordanian university students' preferences for cold and flu treatment.
PLoS One. 2026;21:e0358179.
PubMed Abstract available

SUERDEM A, Zdravkov S, Ivanov MJ
Beyond deficit and coexistence: Modeling the knowledge-conspiracy-mistrust configuration in public understanding of science.
PLoS One. 2026;21:e0341946.
PubMed Abstract available

GWANZURA TNR, Trepka MJ, Li T, Juhasz L, et al
COVID-19 mortality risk among people with HIV in Florida before and after the introduction of COVID-19 vaccines: A population-based study.
PLoS One. 2026;21:e0358543.
PubMed Abstract available

DE VERAS BMG, Michelin L, Croda J, Berra TZ, et al
Burden of respiratory syncytial virus (RSV) hospitalizations among adults aged 60 years or more in Brazil: A retrospective surveillance database analysis (2013-2024).
PLoS One. 2026;21:e0357303.
PubMed Abstract available

Vaccine

HOEN L, Lartey S, Pathirana RD, Cox RJ, et al
Elucidating the role of pre-existing immunity in mucosal lymphoid architectural dynamics following live attenuated influenza vaccination.
Vaccine. 2026;92:129139.
PubMed Abstract available

GUO J, Dai C, Huang Y, Dai J, et al
Preclinical toxicity and immunogenicity of a quadrivalent recombinant influenza hemagglutinin vaccine (SCVC101) in rhesus monkeys.
Vaccine. 2026;92:129137.
PubMed Abstract available

LAOHARATTANAHIRUN N, Kiertiburanakul S, Boonnak K, Bruminhent J, et al
Immunogenicity and safety of high-dose versus standard-dose quadrivalent inactivated influenza vaccine in patients living with HIV: a randomized controlled trial.
Vaccine. 2026;92:129166.
PubMed Abstract available

OSTROWSKY JT, Gellin BG, Cavaleri M, Bresee JS, et al
Innovation, development, and licensure of improved influenza vaccines: the way forward.
Vaccine. 2026;92:129135.
PubMed Abstract available

ZHOU B, Wang J, Knote C
Seasonal influenza vaccination coverage and population health burden in Europe during the 2019/2020 and 2021/2022 influenza seasons: an ecological panel analysis using principal-component-adjusted multivariable regression.
Vaccine. 2026;92:129163.
PubMed Abstract available

Giuseppe Michieli

Sunday, September 13, 2026

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, September 13 '26)

Antimicrob Agents Chemother

PENG Z, Yuan H, Huang J, Lin X, et al
A novel ursodeoxycholic acid derivative exhibits broad-spectrum antiviral activity against influenza A virus and coronaviruses by multiphasic disruption of the viral life cycle.
Antimicrob Agents Chemother. 2026 Sep 9:e0028426. doi: 10.1128/aac.00284.
PubMed Abstract available

BMC Pediatr

BOZZOLA E, Piccotti E, D'Auria E, Trapani S, et al
RESPIRIAMO - Italian hospital surveillance for lower respiratory tract infections: a multicenter retrospective cohort study of respiratory syncytial virus-associated hospitalizations in children under 2 years of age.
BMC Pediatr. 2026;26:853.
PubMed Abstract available

J Infect

ZHU X, Deng Y, Xiao G, Zhang J, et al
Re-emergence of H10N3 Avian Influenza Viruses in China: Evolutionary Dynamics and Emerging Zoonotic Risk.
J Infect. 2026 Sep 7:106848. doi: 10.1016/j.jinf.2026.106848.
PubMed

J Virol Methods

EZEANYAEGBU CN, Toledo NP, Corkum CP, Nelder M, et al
Evaluation of one-step amplicon-based targeted enrichment for SARS-CoV-2 whole-genome sequencing using the Midnight amplicon scheme.
J Virol Methods. 2026;346:115448.
PubMed Abstract available

KAZEMIAN S, Pedroza S, Santana-Pereira ALR, Neasham PJ, et al
An enhanced multisegment RT-PCR method for influenza A virus sequencing: Improved performance and reduced preparation time over traditional methods.
J Virol Methods. 2026;347:115453.
PubMed Abstract available

PLoS Comput Biol

QUILTY BJ, Chapman LAC, Munday JD, Wong KLM, et al
Disentangling the drivers of heterogeneity in SARS-CoV-2 transmission from data on viral load and daily contact rates.
PLoS Comput Biol. 2026;22:e1014715.
PubMed Abstract available

SONG P, de Vlas SJ, Emery T, Coffeng LE, et al
Mapping spatial colleague connectivity patterns from individual-level registry data to inform regional pandemic interventions.
PLoS Comput Biol. 2026;22:e1014721.
PubMed Abstract available

PANT B, Lalovic M, Kiss IZ, Santillana M, et al
The paradox of neglecting changes in behavior: How standard epidemic models misestimate both transmissibility and final epidemic size.
PLoS Comput Biol. 2026;22:e1014746.
PubMed Abstract available

YUAN Z, Zhang X, Lin G, Zou Q, et al
AET5: A transcriptome-guided molecular generation framework with contrastive self-supervised learning.
PLoS Comput Biol. 2026;22:e1014703.
PubMed Abstract available

BENHAMOU W, Howerton E, Park SW, Viboud C, et al
Leveraging perturbations to infer the population dynamics of human rhinovirus and interaction of influenza A virus.
PLoS Comput Biol. 2026;22:e1014784.
PubMed Abstract available

PLoS Med

LENGLART L, Titomanlio L, Alberti I, Almeida L, et al
Association between nirsevimab coverage and pediatric emergency department visits for bronchiolitis in 12 European countries: An interrupted time-series analysis.
PLoS Med. 2026;23:e1005223.
PubMed Abstract available

PLoS One

KWON K, Jang CY, Kim W, Son J, et al
Kinetics of the PASC Index in Long COVID.
PLoS One. 2026;21:e0357670.
PubMed Abstract available

BATTU S, Moore AR, Lebold K, Pacheco-Navarro A, et al
Outcomes of immunocompromised and non-immunocompromised patients in the ICU diverge late in the pandemic.
PLoS One. 2026;21:e0357181.
PubMed Abstract available

JI M, Dong H, Xu Y, Wang Y, et al
Development of a multiplex real-time PCR assay with fluorescence probe-melting-curve analysis for one-tube detection of respiratory pathogens.
PLoS One. 2026;21:e0357377.
PubMed Abstract available

GONG X, Liu L, Lu Y, Zhang G, et al
Sleepless in America: A social sensing study of pandemic-era sleeplessness using nighttime social media data.
PLoS One. 2026;21:e0356547.
PubMed Abstract available

BHATIA A, Elser J, Carrell SJ, Kronmiller B, et al
Correlation assessment of SARS-CoV-2 variants and their subvariants present in clinical and wastewater samples in Oregon, USA (February 7, 2021 - February 26, 2022) using the Freyja bioinformatics approach.
PLoS One. 2026;21:e0357591.
PubMed Abstract available

MOHD YUSOFF H, Yew SQ, Mohd Nawi A, Mohd Tohit N, et al
Prevalence and risk factors of adverse work outcomes among manufacturing workers with Long COVID in Malaysia - A nationwide study.
PLoS One. 2026;21:e0357125.
PubMed Abstract available

VALDES-LOPEZ JF, di Filippo D, Penagos S, Hernandez-Sarmiento LJ, et al
SARS-CoV-2 infection induces functional impairment of vitamin D receptor signaling to drive interleukin 6-dependent hyperinflammation in mononuclear phagocytes.
PLoS One. 2026;21:e0357030.
PubMed Abstract available

AMARSANAA J, Nguyen TXT, Khan MSR, Kadoya Y, et al
The dynamics of loneliness: A longitudinal exploration of transitions in Japan across the COVID-19 period, 2020-2024.
PLoS One. 2026;21:e0358269.
PubMed Abstract available

Proc Natl Acad Sci U S A

LI L, Nguyen L, Qu H, Wu Q, et al
Increased receptor binding and spike glycosylation, remodeled immune escape of surging SARS-CoV-2 subvariant BA.3.2.2/RE.2.2/Cicada.
Proc Natl Acad Sci U S A. 2026;123:e2614163123.
PubMed Abstract available

Vaccine

BUCKLIN R, Gauthreaux N, Faber E, Askelson N, et al
Listening to micropolitan community leaders to support pandemic response efforts.
Vaccine. 2025;60 Suppl 1:127255.
PubMed Abstract available

HOLLIDAY RC, Darkwa A, Brooks GA, Akintobi TH, et al
Developing counter-narratives to address COVID-19 misinformation among 18-24 year olds in community and campus settings.
Vaccine. 2025;60 Suppl 1:127135.
PubMed Abstract available

HEIMAN SL, Geiger N
Overestimation of racial ingroup worry about the COVID-19 vaccine and medical racism.
Vaccine. 2026;91:129046.
PubMed Abstract available

DUTTA S, Ngemera D, Jaillard P, Juneja S, et al
Lessons learnt from one-year cold chain support for COVID-19 vaccination in 5 middle income countries of North Africa.
Vaccine. 2026;91:128994.
PubMed Abstract available

CAMPBELL STATLER M, Bishop-Royse J, Sampson AT, Martin M, et al
Heterogeneity among the vaccine hesitant: A secondary analysis of the national CEAL Common Survey data.
Vaccine. 2026;91:129024.
PubMed Abstract available

KIM SJ, Kim HW, Son SE, Song JH, et al
Wuhan-ancestral multi-antigen SARS-CoV-2 virus-like particles protect against the omicron sublineage JN.1 variant.
Vaccine. 2026;91:129059.
PubMed Abstract available

FAHFOUHI Y, Fievez S, Cohen R, Levy C, et al
A health-economic assessment of the impact of different RSVpreF maternal vaccine strategies to prevent RSV infections among young infants, in France: EPIPACT.
Vaccine. 2026;91:129036.
PubMed Abstract available

BERIKOPOULOU MM, Tatsi EB, Siahanidou T, Michos A, et al
Systematic review of the mutations in the active antigenic site O of the prefusion F protein of the Respiratory Syncytial Virus (RSV) following the implementation of monoclonal antibody prophylaxis.
Vaccine. 2026;91:129069.
PubMed Abstract available

NUNES JPDS, Daher IP, Pires ADS, Yamamoto MM, et al
Synergistic effect of AddaS03 and poly I:C adjuvants on antibody titers and Th1-biased T cell responses following RBD vaccination in BALB/c mice.
Vaccine. 2026;91:129073.
PubMed Abstract available

MONOI A, Endo A, Kriznar M, Suzuki M, et al
Comparing the potential impacts of seasonal immunisation against year-round immunisation to prevent RSV infant hospitalisations in Japan: A modelling study.
Vaccine. 2026;91:129079.
PubMed Abstract available

SCHRARSTZHAUPT IN, Diaz-Quijano FA
Effectiveness of COVID-19 vaccination schedules against severe COVID-19 in children aged 6 months to 4 years in Brazil: A population-based cohort study (2023-2024).
Vaccine. 2026;91:129096.
PubMed Abstract available

ALAMI A, Lewis M, El-Chaar D, Walker M, et al
Maternal vaccination with RSVpreF and risk of hypertensive disorders of pregnancy: a systematic review and meta-analysis.
Vaccine. 2026;91:129070.
PubMed Abstract available

DENG L, Ye X, Chen X, Hu X, et al
Secretory expression of tetrameric neuraminidase enhanced by signal peptide optimization elicits robust immunity against influenza infection in mice.
Vaccine. 2026;92:129118.
PubMed Abstract available

SANBORN J, Robertson MM, Penrose K, Rane M, et al
Gaps between willingness and uptake of influenza and COVID-19 vaccines during the 2025-26 respiratory virus season in a U.S. adult cohort.
Vaccine. 2026;92:129126.
PubMed Abstract available

LU J, Ouyang Z, Huang F, Xie X, et al
Real-world effectiveness of the influenza vaccine among school-aged children in Shenzhen, China, 2024-2025 season: A test-negative design study.
Vaccine. 2026;92:129100.
PubMed Abstract available

THAKKAR V, Aryan Y, Gautam S, Joshi R, et al
Influence of vaccine delivery route on immune imprinting in influenza vaccination.
Vaccine. 2026;92:129109.
PubMed Abstract available

TORAIH EA, Hussein MH, Thomas SJ, Aiash H, et al
Cardiac outcomes following SARS-CoV-2 infection versus BNT162b2 vaccination in adolescents and young adults: a cohort study of 4 million individuals.
Vaccine. 2026;91:129001.
PubMed Abstract available

CABURNAY CA, Fu QJ, Carter T, Butler T, et al
Identification of best outreach strategies and delivery modalities for population subgroups for COVID-19 vaccination.
Vaccine. 2026;60 Suppl 1:128721.
PubMed Abstract available

CANACA G, Vicuna B, Hess JM, Cruz TH, et al
From engagement to ownership: a qualitative study of a community-academic partnership to promote COVID-19 vaccine confidence among Latino/Hispanic communities in New Mexico.
Vaccine. 2026;60 Suppl 1:128583.
PubMed Abstract available

STIEHL E, Negrete M, Flores G, Federmeyer L, et al
Empowering communities during the COVID-19 pandemic: insights from trusted messengers about their work addressing COVID-19 vaccine hesitancy.
Vaccine. 2026;60 Suppl 1:128559.
PubMed Abstract available

NUNO T, Soto S, Sepulveda R, Sierra LA, et al
The Arizona prevention research center vaccine confidence network: A Mobile health unit intervention and survey results of barriers and facilitators to COVID-19 vaccination.
Vaccine. 2025;60 Suppl 1:127970.
PubMed Abstract available

HARA-HUBBARD KK, Beaulieu A, Mendiola A, Gandhi P, et al
Strategies for addressing COVID-19 vaccine equity with intermediaries, prevention research centers, and the vaccine confidence network.
Vaccine. 2025;60 Suppl 1:127847.
PubMed Abstract available

CHUVILEVA YE, Kuiper NM, Ramakrishnan A, Goodman K, et al
Weaving a public health network: Process and results from an evaluation of CDC's Prevention Research Centers Vaccine Confidence Network.
Vaccine. 2025;60 Suppl 1:127636.
PubMed Abstract available

ALMUKHTAR S, McWhirter N, Mendiola A, Samuel S, et al
Exploring lingering COVID-19 vaccine hesitancy in three diverse U.S. states: Alabama, Illinois, and Texas.
Vaccine. 2025;60 Suppl 1:127664.
PubMed Abstract available

BEAULIEU A, LaMonaca K, Higginbottom J, Foster J, et al
Utilizing the Program Impact Pathways framework for improving COVID-19 vaccine confidence and uptake: demonstrations of multi-sector collaboration from two geographies in Connecticut.
Vaccine. 2025;60 Suppl 1:127623.
PubMed Abstract available

JEFFERS A, Kuiper NM, Ramakrishnan A, Swarna H, et al
Building trust in community-academic partnerships: Strategies for enhancing vaccine confidence and demand - Lessons from Prevention Research Centers.
Vaccine. 2025;60 Suppl 1:127624.
PubMed Abstract available

MCGEE RE, Barrett DA, Bednarczyk RA, Grant-Whitlock M, et al
Engaging rural and non-Hispanic Black persons in conversations about the COVID-19 vaccine: a process evaluation of a natural helper intervention.
Vaccine. 2025;60 Suppl 1:127587.
PubMed Abstract available

BORG A, Goulding M, Minkah P, Perrone D, et al
Promotion of COVID-19 vaccination for youth and families in Worcester, Massachusetts: a Diffusion of Innovations approach.
Vaccine. 2025;60 Suppl 1:127586.
PubMed Abstract available

SAVAS LS, Cuccaro P, Zhang K, Hernandez R, et al
Factors influencing COVID-19 vaccine uptake among vulnerable communities in Texas: Perceptions of 2-1-1 helpline callers.
Vaccine. 2025;60 Suppl 1:127554.
PubMed Abstract available

TOTZKAY D, Fraustino JD, Costello LM, Jarrett T, et al
Building on West Virginia's innovative COVID-19 public health communication: associations between vaccination beliefs and vaccination messaging, partisanship, and social vulnerability.
Vaccine. 2025;60 Suppl 1:127555.
PubMed Abstract available

O'CONNOR MH, Nyman AL, Ali S, Rothenberg R, et al
Increasing vaccine uptake in a refugee resettlement community with high social vulnerability.
Vaccine. 2025;60 Suppl 1:127552.
PubMed Abstract available

STIEHL E, Borg A, Cullen JP, Mendiola A, et al
Engaging trusted messengers in public health response: Key strategies to building community trust among CDC'S prevention research center's vaccine confidence network.
Vaccine. 2025;60 Suppl 1:127474.
PubMed Abstract available

HARA-HUBBARD KK, Flores Moreno MG, Sanchez M, Abdi N, et al
The partnership for vaccine confidence: community-academic partnerships to promote COVID-19 vaccines to underserved urban and rural communities using the listen, plan, act, evaluate process.
Vaccine. 2025;60 Suppl 1:127487.
PubMed Abstract available

MALLICK K, Handunge VL, Emmons KM, Blondet L, et al
Engaging a community health ambassador model to promote COVID-19 vaccine in three Massachusetts communities.
Vaccine. 2025;60 Suppl 1:127464.
PubMed Abstract available

Virology

ISHIGAKI H, Otaki K, Kitagawa N, Ishida H, et al
Pathogenicity of SARS-CoV-2 Omicron subvariants JN.1, EG.5.1, and BA.2.86.1 in immunologically naive cynomolgus macaques.
Virology. 2026;624:111036.
PubMed Abstract available

LIU Z, Fan M, Zheng Y, Zeng Y, et al
Transcriptome screening identifies circRNA-INSR as a novel host factor associated with avian influenza virus replication.
Virology. 2026;625:111072.
PubMed Abstract available

MILLER AK, Heremia L, Waller SJ, Blanchard SL, et al
Evaluating sampling strategies for the detection of avian influenza viruses in the environment.
Virology. 2026;625:111069.
PubMed Abstract available

Virus Res

ZHAO Y, Fan H
Clinical impact of baloxavir-induced PA I38T/M substitutions in diverse influenza populations: a systematic review and meta-analysis.
Virus Res. 2026;373:199797.
PubMed Abstract available

Giuseppe Michieli

Saturday, September 5, 2026

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, Sept. 5 '26)

Antimicrob Agents Chemother

DE ANGELIS M, Gori Savellini G, Piselli E, Anichini G, et al
Redox-sensitive factors as targets of thiol compounds to hinder SARS-CoV-2 replication and inflammatory response.
Antimicrob Agents Chemother. 2026;70:e0051826.
PubMed Abstract available
JEENA N, Khan IA
Targeting SARS-CoV-2 programmed -1 ribosomal frameshifting: structural dynamics and RNA-directed antiviral strategies.
Antimicrob Agents Chemother. 2026;70:e0068726.
PubMed Abstract available
AVILA-PONCE DE LEON U, Esmaeili S, Owens K, Schiffer JT, et al
Plasma concentrations of nirmatrelvir and molnupiravir required for inhibition of SARS-CoV-2 replication differ between rhesus macaques and humans.
Antimicrob Agents Chemother. 2026 Aug 5:e0030726. doi: 10.1128/aac.00307.
PubMed Abstract available

Antiviral Res
PU F, Guo Y, Pan X, Liu X, et al
Dual-targeting engineered binding proteins block SARS-CoV-2 infection and complement activation.
Antiviral Res. 2026;254:106515.
PubMed Abstract available
YURGELONIS I, Rai DK, Lee JT, Li Z, et al
Antiviral activity of nirmatrelvir against contemporary SARS-CoV-2 variants.
Antiviral Res. 2026;254:106517.
PubMed Abstract available

Epidemiol Infect
NAQVI OH, Wendelboe AM, Beasley WH, Tyungu DL, et al
Epidemiological characteristics of paediatric COVID-19 and influenza co-infections in the United States, 2020-2024 - CORRIGENDUM.
Epidemiol Infect. 2026;154:e111.
PubMed

J Infect Dis
ZHAO B, Zhang G, Wu J, Zhang W, et al
Characterization of bronchiolitis and vaccine-induced enhanced respiratory disease in Syrian hamsters caused by respiratory syncytial virus infection.
J Infect Dis. 2026 Mar 4:jiag136. doi: 10.1093.
PubMed Abstract available

J Virol
BHAVSAR D, Civljak A, Bonnettaz B, Arunkumar GA, et al
Broadly reactive antibodies against influenza B virus hemagglutinin neutralize and protect through distinct structural mechanisms.
J Virol. 2026 Sep 4:e0080226. doi: 10.1128/jvi.00802.
PubMed Abstract available
LIU D, Zhang Y, Zhang M, Guo R, et al
A neuraminidase-targeting nanobody as a therapeutic candidate against influenza A and B viruses.
J Virol. 2026 Aug 31:e0087426. doi: 10.1128/jvi.00874.
PubMed Abstract available

JAMA
SENERTH E, Sheikholeslamian SM, Sivakumaran K, Watson MA, et al
Influenza Vaccine Effectiveness and Safety for the 2026-2027 Respiratory Season.
JAMA. 2026 Sep 2. doi: 10.1001/jama.2026.18126.
PubMed Abstract available

Pediatrics
CHAN OW, Cheng YT, Liu YH, Chou IJ, et al
Anakinra in Severe RSV-Associated Autoinflammatory Encephalopathy With Delayed ADEM-Like Changes.
Pediatrics. 2026;158:e2026076364.
PubMed Abstract available
PAYNE AB, Battan-Wraith S, Reese SE, Hathaway CA, et al
Effectiveness of RSV Prevention Strategies in US Infants: 2024-2025.
Pediatrics. 2026 Aug 4:e2026076089. doi: 10.1542/peds.2026-076089.
PubMed Abstract available
MIN J, Tam V, Jacoby SF, McDonald CC, et al
Community Firearm Violence, Youth Depression, and Suicide Risk in Philadelphia: 2017-2024.
Pediatrics. 2026;158:e2025075438.
PubMed Abstract available

PLoS Comput Biol
FREEDMAN AS, Nielsen BF, Saad-Roy CM, Grenfell BT, et al
Economic factors promoting vaccine nationalism in the face of viral evolution.
PLoS Comput Biol. 2026;22:e1014466.
PubMed Abstract available

PLoS Med
ELIAS KM, Mitchell A, Stadler E, Schlub TE, et al
Neutralising antibodies and protection from progression to severe COVID-19: A meta-analysis.
PLoS Med. 2026;23:e1005230.
PubMed Abstract available

PLoS One
ADAMCZYK G, Jablonski A, Nowakowski PT, Ptaszek RT, et al
Theodicy perspective as an effect of the interpenetration of mental and religious issues during the COVID-19 pandemic in Poland.
PLoS One. 2026;21:e0355379.
PubMed Abstract available
JUNGMANN SM, Garbe Huedo SF, Jacobs KAS, Pothorn NK, et al
Mental load in women and mothers: Causes of distress, personality traits, and psychopathology.
PLoS One. 2026;21:e0356255.
PubMed Abstract available
MOUNADI N, Nour H, El Kouali M, Samadi A, et al
Repositioning antiviral phytoconstituents as broad-spectrum inhibitors of influenza A neuraminidase and human metapneumovirus fusion protein.
PLoS One. 2026;21:e0348517.
PubMed Abstract available
HAWKES BA, Hollister J, Porter C, Lyski ZL, et al
Age-specific humoral immune response to SARS-CoV-2: A comparative analysis of antibody levels in children and adults after vaccination with primary series or infection.
PLoS One. 2026;21:e0356178.
PubMed Abstract available
AVSAR FN, Kilicaslan N, Sahutoglu T
Comparative associations of Anakinra and Tocilizumab initiation with in-hospital mortality in severe COVID-19: A single-center sequential cohort study.
PLoS One. 2026;21:e0357671.
PubMed Abstract available
SEEGERT N, Gaulin M, Chaiyakunapruk N, Navarro-Sanchez F, et al
The impact of state- versus county-level mask mandates on economic activity during the COVID-19 pandemic.
PLoS One. 2026;21:e0332243.
PubMed Abstract available
HARDY MJ, Williams CK, Ladman BS, Pitesky ME, et al
Using high frequency GPS data to assess wintering goose proximity to commercial poultry facilities on the Delmarva peninsula for avian influenza risk management and surveillance.
PLoS One. 2026;21:e0355415.
PubMed Abstract available
KOPP J, Spies Rodriguez DC, Kunzi L, Puhan MA, et al
Physical activity in post-COVID-19 condition: A cross-sectional study.
PLoS One. 2026;21:e0357465.
PubMed Abstract available

Proc Natl Acad Sci U S A
KARADAKIC R, Keating NL, Barnett ML
Interpreting vaccine-associated survival differences in immune checkpoint inhibitor therapy.
Proc Natl Acad Sci U S A. 2026;123:e2621501123.
PubMed Abstract available

Vaccine
MOHAMMED H, Andraweera P, Marshall HS
A cohort study to assess the safety and coverage of COVID-19, influenza, and pertussis vaccine in Australian pregnant women.
Vaccine. 2026;91:129081.
PubMed Abstract available
SHEN AK, Tupps C, Bino S, Chipoya M, et al
Investments in seasonal influenza vaccination programs pack a punch for pandemic preparedness.
Vaccine. 2026;92:129098.
PubMed Abstract available
TRAN S, McClymont E, Blitz S, Barrett J, et al
Self-reported reactogenicity after COVID-19 vaccination with and without influenza vaccine coadministration during pregnancy in Canada.
Vaccine. 2026;92:129122.
PubMed Abstract available
MARIA DA, Martins IM, Porto GPM, Villas-Boas IM, et al
Safety, humoral and cellular immune responses to a pre-pandemic adjuvanted influenza A (H5N8) vaccine.
Vaccine. 2026;92:129049.
PubMed Abstract available
ZHENG Y, Qiao B, Gao Z, Zhang X, et al
Development of a subunit vaccine candidate (RBD-HA trimer) provides dual protection against multi-subtype avian influenza viruses and QX-type infectious bronchitis virus.
Vaccine. 2026;92:129121.
PubMed Abstract available
KORNUTA CA, Zhou G, Kane KP, Vliagoftis H, et al
Mucosal adjuvant activity of a PAR-2-activating peptide enhances lymph node immune cell recruitment and promotes immune cell activation in a prime-boost influenza vaccination model.
Vaccine. 2026;92:129110.
PubMed Abstract available

Virology
BROGAARD L, Laybourn HA, Kristensen C, Welner S, et al
Site-specific microRNA responses in lungs of pigs depend on the host-adaptation of H1N1 influenza A virus.
Virology. 2026;624:111053.
PubMed Abstract available
SEKINE W, Kamiki H, Ishida H, Matsugo H, et al
HA1-T138A and HA1-Q226L substitutions in H3N2 canine influenza virus contribute to binding to human-type alpha2,6-linked sialic acid receptors.
Virology. 2026;625:111071.
PubMed Abstract available
OLDENSAND F, Rafati N, Van Hoef V, Lundkvist A, et al
Single-cell transcriptomic landscape of avian influenza H9N2 virus infection in human and chicken cells.
Virology. 2026;625:111070.
PubMed Abstract available

Giuseppe Michieli

Monday, August 31, 2026

#Antibody profiles across #H5N1 and previously circulating viruses are highly dynamic and #age- and imprint- independent

Abstract

The increasing incidence of H5N1 influenza virus transmission from animal species to humans has heightened concerns about an imminent H5N1 pandemic. Prior studies using recombinant hemagglutinin and neuraminidase proteins have reported age-dependent cross-reactivity to H5N1, attributed to immune imprinting from an individual's first influenza virus exposure. However, whether this pattern holds when using whole inactivated virus (WIV), capturing antibodies against diverse viral proteins, and is stable over time remains unknown. We therefore aimed to determine whether H5N1 cross-reactivity of pre-existing antibodies to whole virus follows an age-dependent or imprinting-specific pattern, and whether this pattern is stable over a five-year period. To this end, we measured serum antibody levels in adolescents, adults and seniors by ELISA using whole inactivated H5N1 virus as antigen rather than purified proteins. Detectable, albeit generally low, levels of H5N1-reactive antibodies were present in most individuals, irrespective of age. Comparison of antibody levels against H5N1 with those to five historical influenza virus strains revealed a consistent positive correlation between H5N1-reactive antibodies and responses to the H1N1pdm09 strain A/California/7/2009 (CA), across all age groups. Using unbiased clustering of antibody titers against H5N1, CA, and the H3N2 strain A/Perth/16/2009 (PE), we identified seven distinct age-transcending antibody profiles. These profiles covered individuals with varying titers to all three included viruses but also identified individuals with high anti-CA levels, yet low anti-H5N1 levels and vice versa. Moreover, despite stable antibody levels over a five-year interval in the study population, individual antibody levels and profiles fluctuated considerably over this period. Taken together, our results confirm the presence of H5N1-reactive antibodies in human sera and their association with previously circulating strains. However, they also caution against inferring antibody levels against a new strain based solely on responses to antigenically related strains and highlight the limitations of extrapolating immune status from single timepoint measurements.

Competing Interest Statement

The authors have declared no competing interest.

Source:

Link: https://www.medrxiv.org/content/10.64898/2026.08.26.26361396v1

____

Giuseppe Michieli

ETIDIOH - NEW

Saturday, October 3, 2026

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, Oct. 3 '23)

Saturday, September 26, 2026

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, September 26 '26)

Monday, September 21, 2026

Limited added #benefit of seasonal #influenza #vaccination before #H5 vaccination in mice and #ferrets challenged with #H5N1

Saturday, September 19, 2026

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, September 19 '26)

Sunday, September 13, 2026

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, September 13 '26)

Saturday, September 5, 2026

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, Sept. 5 '26)

Monday, August 31, 2026

#Antibody profiles across #H5N1 and previously circulating viruses are highly dynamic and #age- and imprint- independent

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