#Influenza and Other Respiratory Viruses Research #References (AMEDEO, August 16 '26)-

 

Biochem Biophys Res Commun

1. RAO RM, Kumar N, P SP, Rao MJ, et al
   Convergent genetic and structural parameters of cardiovascular disease related insights of post-acute COVID-19.
   Biochem Biophys Res Commun. 2026;831:154319.
   PubMed         Abstract available
   
   
2. LIU C, Yan Z, Tao Z, Yang W, et al
   C5a-C5aR1 axis activation drives neutrophil extracellular trap formation in SARS-CoV-2 N protein-mediated acute kidney injury.
   Biochem Biophys Res Commun. 2026;831:154305.
   PubMed         Abstract available
   
   

   
   J Clin Microbiol

3. AEBISCHER A, Gunther A, Piesche R, Wernike K, et al
   Development of a multi-species luciferase-based double-antigen ELISA for the detection of antibodies against influenza A virus H5 clade 2.3.4.4b.
   J Clin Microbiol. 2026 Aug 13:e0190725. doi: 10.1128/jcm.01907.
   PubMed         Abstract available
   
   

   
   J Gen Virol

4. LOZANO-MONTALBA L, Denis Z, Courgnaud V, Moreno-Garcia J, et al
   Glycosphingolipids are essential entry factors for non-influenza orthomyxoviruses.
   J Gen Virol. 2026;107.
   PubMed         Abstract available
   
   

   
   J Immunol

5. MCKERNAN KE, Cephus JY, Kuehnle SN, Henriquez-Pilier E, et al
   Deficiency in circulating T cells in four core genotypes mice with Sry translocation.
   J Immunol. 2026;215:vkag207.
   PubMed         Abstract available
   
   

   
   J Infect

6. HANSEN CL, Shaikh N, Naeger S, Torcel-Pagnon L, et al
   Hospitalizations and deaths from major respiratory viruses in the US: An ensemble time series modeling study, 2016-2025.
   J Infect. 2026;93:106811.
   PubMed         Abstract available
   
   
7. VINK E, Murphy ME, Gunson R, MacConnachie A, et al
   Respiratory viral detection in adult severe acute respiratory infection post-COVID-19 pandemic: implications for antimicrobial stewardship.
   J Infect. 2026;93:106805.
   PubMed         Abstract available
   
   
8. RAN J, Zhu L, Ning M, Zhang W, et al
   Age-associated impairment of humoral and cellular immune responses to SARS-CoV-2 in a large community cohort with hybrid immunity.
   J Infect. 2026 Jul 1:106803. doi: 10.1016/j.jinf.2026.106803.
   PubMed         Abstract available
   
   
9. KONG M, Gao HX, Song XD, Yang GJ, et al
   Convergent neutralizing antibodies to SARS-CoV-2 variants over 2.5 years after BA.5/BF.7 breakthrough infection.
   J Infect. 2026 Jun 18:106799. doi: 10.1016/j.jinf.2026.106799.
   PubMed         Abstract available
   
   
10. ATUKORALE VN, Kwong JC, Hernandez A, Moineddin R, et al
    Factors associated with severe health outcomes among community-dwelling older adults hospitalized with respiratory syncytial virus.
    J Infect. 2026;93:106797.
    PubMed         Abstract available
    
    
11. DONG S, Li M, Huo D, Zhao H, et al
    Impact of EV-A71 vaccination and non-pharmaceutical interventions on hand, foot, and mouth disease: A 14-year interrupted time series analysis.
    J Infect. 2026;93:106795.
    PubMed         Abstract available
    
    
12. TRUONG T, Radin JM, Li L, Ordonez-Mena JM, et al
    Burden and economic impact of RSV hospitalisations among English adults, 2023/24.
    J Infect. 2026;93:106792.
    PubMed         Abstract available
    
    
13. WANG X, Yin J, Xu B, Guanhua X, et al
    Clinical epidemiological characteristics of hospitalized pediatric Mycoplasma pneumoniae pneumonia in China.
    J Infect. 2026 Jun 10:106793. doi: 10.1016/j.jinf.2026.106793.
    PubMed         Abstract available
    
    

    
    J Virol

14. PULIT-PENALOZA J, Belser JA, Brock N, Kieran TJ, et al
    Risk assessment of avian influenza A(H5N5) virus from the first human case using the ferret model.
    J Virol. 2026 Aug 11:e0085626. doi: 10.1128/jvi.00856.
    PubMed         Abstract available
    
    

    
    N Engl J Med

15. LIU Z, Zhang L, Jiang M
    Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults.
    N Engl J Med. 2026;395:724.
    PubMed        
    
    
16. LOCQUET M, Dogne JM
    Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults.
    N Engl J Med. 2026;395:724-725.
    PubMed        
    
    
17. HUANG G, Das R, Wilson E
    Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults. Reply.
    N Engl J Med. 2026;395:725-726.
    PubMed        
    
    

    
    Pediatrics

18. 
    Recommendations for Prevention and Control of Influenza in Children, 2026-2027: Policy Statement.
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    PubMed         Abstract available
    
    
19. 
    Recommendations for Prevention and Control of Influenza in Children, 2026-2027: Technical Report.
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    PubMed         Abstract available
    
    

    
    PLoS Comput Biol

20. FORNA A, Damodaran L, Gunning CE, Rahimi P, et al
    Alignment-free prediction of cross-reactivity in influenza A (H3N2) anticipates antigenic drift.
    PLoS Comput Biol. 2026;22:e1014628.
    PubMed         Abstract available
    
    

    
    PLoS One

21. MURPHY C, Cheng SMS, Mak L, So HC, et al
    Diagnostic agreement between Rhinoswabs and joint nose and throat swabs for the detection of influenza and SARS-CoV-2 among symptomatic ambulatory patients in Hong Kong.
    PLoS One. 2026;21:e0355869.
    PubMed         Abstract available
    
    
22. KILDAY D, Korvink M, Tatum D, Cao Z, et al
    Association between COVID-19 by variant period and delivery-related outcomes in the United States.
    PLoS One. 2026;21:e0355223.
    PubMed         Abstract available
    
    
23. TAMAKI S, Kawashima R, Uematsu T, Kawakami F, et al
    Eosinophil-associated intestinal immune responses following SARS-CoV-2 infection in K18-hACE2 mice.
    PLoS One. 2026;21:e0355607.
    PubMed         Abstract available
    
    
24. PIETAN L, Phillippi E, Melo M, El-Shanti H, et al
    Genome-wide machine learning analysis of anosmia and ageusia with COVID-19.
    PLoS One. 2026;21:e0355832.
    PubMed         Abstract available
    
    
25. CHEN PY, Dang LH, Hung SH
    The association between meteorological factors and influenza incidence in Taiwan: Regional heterogeneity and subtropical climate variability.
    PLoS One. 2026;21:e0355559.
    PubMed         Abstract available
    
    
26. PARK S, Kwon JA, Kim HS, Choi Y, et al
    Socioeconomic differences in influenza vaccination coverage by government financial support status: A population-based study in Korea.
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    PubMed         Abstract available
    
    
27. ALSHAHRANI A, Reddy RS, Gular K, Kakaraparthi VN, et al
    Postural control and trunk mobility impairments in adults with long COVID: A cross-sectional study using computerized posturography and clinical biomechanical tools.
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    PubMed         Abstract available
    
    
28. TUT G, Lancaster T, Sylla P, Bone D, et al
    High rates of SARS-CoV-2 reinfection in residents of long term care facilities despite robust spike-specific immunity following serial vaccination.
    PLoS One. 2026;21:e0354079.
    PubMed         Abstract available
    
    
29. KIM Y, Lee J, Park J
    Concentration of hospital utilization in the capital area among elderly inpatients from non-capital regions in South Korea: Before and during the COVID-19 pandemic.
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    PubMed         Abstract available
    
    
30. FREIRE SF, Shimizu IS, Lima CAS, Adhikari NKJ, et al
    The association between resource availability and knowledge, attitudes, and practice about protective ventilation among ICU directors - A nationwide cross-sectional survey.
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    PubMed         Abstract available
    
    
31. KARADUMAN E, Toprak N, Cevik A, Erail S, et al
    Factors associated with fear and coping strategies during pandemic in female university students: The moderator role of physical activity and infection status.
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    PubMed         Abstract available
    
    
32. IRIEMENAM NC, Osawe S, Akanbi OA, Akinmulero O, et al
    High prevalence of SARS-CoV-2 antibodies among frontline healthcare workers during the COVID-19 pandemic in three states of Nigeria from August to December 2022.
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    PubMed         Abstract available
    
    

    
    Proc Natl Acad Sci U S A

33. DIAZ TOVAR JS, Dos Reis FP, Moriyama LT, Pego-Fernandes PM, et al
    Anatomy-resolved digital twin framework for personalized light dosimetry in lung therapies.
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    PubMed         Abstract available
    
    

    
    Vaccine

34. GEBREMARIAM AG, Genie M, Le H, Regan A, et al
    Vaccine uptake in the context of mandate announcement and removal: Evidence from Europe and North America.
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    PubMed         Abstract available
    
    
35. FAVRE G, Pfund A, Gerbier E, Anselem O, et al
    Acceptability and preferences regarding RSV immunisation during pregnancy: a cross-sectional study in diverse global settings.
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    PubMed         Abstract available
    
    
36. CARAZO S, Skowronski DM, Sauvageau C, Talbot D, et al
    2024/25 end-of-season KP.2 vaccine effectiveness against COVID-19 hospitalization in older adults: a test-negative study in Quebec, Canada.
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    PubMed         Abstract available
    
    
37. EBRAHIMI N, de Whalley P, Kanji N, Ramasamy MN, et al
    ChAdOx1 nCoV-19 coronavirus vaccine: Long-term safety and immunological responses.
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    PubMed         Abstract available
    
    
38. DALEXIS RD, Beogo I, Xu Y, Muray M, et al
    Post-COVID-19 pandemic inequities in routine childhood immunization in Canada: racial disparities in uptake of polio, meningococcal conjugate, and varicella vaccines.
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    PubMed         Abstract available
    
    
39. HUSSAIN HS, Yousafzai MT, Iqbal J, Aslam ZM, et al
    Immunogenicity and reactogenicity of fractional vs. full booster doses of COVID-19 vaccines: A non-inferiority, randomized, double-blind, phase IV clinical trial in Pakistan.
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    PubMed         Abstract available
    
    
40. YOON SK, Phillips AL, Battan-Wraith S, Thiese MS, et al
    Real-world effectiveness and safety of protein-based and mRNA COVID-19 vaccines (BEEHIVE trial).
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    PubMed         Abstract available
    
    
41. DIARRA M, Li S, Gaur S, Greenberg P, et al
    Understanding parent motivation for participating in the Pfizer COVID-19 vaccine trial.
    Vaccine. 2026;88:128960.
    PubMed         Abstract available
    
    
42. BELL S, Chantler T, Passanante A, Pryce J, et al
    Maternal respiratory syncytial virus (RSV) vaccine perceptions amongst pregnant women and mothers of infants and toddlers in England: a qualitative study.
    Vaccine. 2026;88:128955.
    PubMed         Abstract available
    
    
43. MAEDA H, Igarashi A, Mitsui S, Suzuki K, et al
    Interim analysis of effectiveness of JN.1-adapted conventional and self-amplifying mRNA COVID-19 vaccines against symptomatic SARS-CoV-2 infection in adults aged >/=60 years, Japan, October 2024-April 2025.
    Vaccine. 2026;88:128964.
    PubMed         Abstract available
    
    
44. BARASA L, Onyango G
    The institutional roots of vaccine uptake and hesitancy: evidence from Africa.
    Vaccine. 2026;88:128980.
    PubMed         Abstract available
    
    
45. LI J, Wang Z, Gong Y
    Country-level immunization recovery and DTP1 no-dose proxy burden after COVID-19: a descriptive ecological analysis of WUENIC, 2010-2024.
    Vaccine. 2026;88:128973.
    PubMed         Abstract available
    
    
46. KIM T, Wang X, Rajtmajer S, Harden JJ, et al
    Elected officials' online anti-vaccination statements respond to online engagement.
    Vaccine. 2026;88:128901.
    PubMed         Abstract available
    
    
47. C M, Dymock M, Flanagan KL, Plebanski M, et al
    The Platform trial In COVID-19 priming and BOOsting (PICOBOO): The immunogenicity, reactogenicity and safety of seven licensed COVID-19 vaccines delivered as fifth dose or subsequent boosters in immunocompetent adults.
    Vaccine. 2026;88:128970.
    PubMed         Abstract available
    
    
48. DE PADUA MC, Antunes MOB, Stein RT, Pinto LA, et al
    Effectiveness of BNT162B2 and CoronaVac vaccines in reducing COVID-19 severity among children aged 3-4 years in Brazil.
    Vaccine. 2026;88:128974.
    PubMed         Abstract available
    
    
49. TAY CJX, Koh CWT, Ooi JSG, Li HE, et al
    Over-induction of innate immune responses suppresses T cell response to mRNA SARS-CoV-2 vaccination.
    Vaccine. 2026;88:128983.
    PubMed         Abstract available
    
    
50. RAFIZADEH A, Wijekoon D, Aung ET, Aguirre I, et al
    Influenza vaccination uptake among people living with HIV in Melbourne, 2015-2025: a repeated cross-sectional study.
    Vaccine. 2026;90:129038.
    PubMed         Abstract available
    
    
51. SAITOH A, Takaku M
    Partner awareness and support for maternal RSV vaccination: a paired survey of pregnant women and co-residing partners in Japan.
    Vaccine. 2026;88:128946.
    PubMed         Abstract available
    
    
52. PAUL KK, Newall AT
    The cost of respiratory syncytial virus (RSV) across all ages to the Australian healthcare system.
    Vaccine. 2026;88:128922.
    PubMed         Abstract available
    
    
53. AUNG TN, Muyindike W, Hoeppner SS, Nanfuka V, et al
    COVID-19 vaccination among people with HIV in Uganda: lessons from a high-risk group with high vaccine uptake for the next pandemic.
    Vaccine. 2026;88:128912.
    PubMed         Abstract available
    
    
54. HENSLEY AA, Jiles KA, Edwards S, Clinchard C, et al
    Characteristics of successful and unsuccessful strategies to increase vaccine intention and improve vaccine uptake for U.S. adult populations in the Affordable Care Act era (2010-2025): a systematic review and meta-regression.
    Vaccine. 2026;88:128910.
    PubMed         Abstract available
    
    
55. MCCONEGHY KW, Wilker EH, DeVone F, Skov B, et al
    Vaccine effectiveness of mRNA-1345 against RSV-associated hospitalization and medically attended acute respiratory illness among US veterans, 2025-2026.
    Vaccine. 2026;88:128882.
    PubMed         Abstract available
    
    
56. NAKANO T, Iwata S, Oishi K, Iguchi E, et al
    Immunogenicity and safety of a SARS-CoV-2 recombinant vaccine S-268024 booster vaccination versus NVX-CoV2373: Interim results from a phase 3, multicenter, randomized, observer-blind, active-controlled study.
    Vaccine. 2026;88:128871.
    PubMed         Abstract available
    
    
57. MALTEZOU HC, Borg M, Botelho-Nevers E, Brantsaeter AB, et al
    Vaccination policies for healthcare personnel in Europe, 2026.
    Vaccine. 2026;88:128839.
    PubMed         Abstract available
    
    
58. MYERS TR, Zauche LH, Marquez PL, McCullum I, et al
    V-safe: Summary of findings reported after COVID-19 vaccination to a US CDC active safety surveillance system through June 2023.
    Vaccine. 2026;88:128725.
    PubMed         Abstract available
    
    
59. PRAT-AYMERICH C, Yeghiazaryan L, Pathirana RD, Gautier V, et al
    A prematurely terminated phase 2, randomised trial to evaluate immunogenicity and reactogenicity of a single versus two-dose primary vaccination regimen of the mRNA vaccine BNT162b2 in previously SARS-CoV-2 infected children 5-11 years old (CoVacc tri
    Vaccine. 2026;88:128769.
    PubMed         Abstract available
    
    
60. SINGER D, La EM, Dubois de Gennes C, Graham J, et al
    Public health impact and cost-effectiveness of adjuvanted RSVPreF3 vaccination among US adults aged 18-49 years at increased risk for severe RSV disease.
    Vaccine. 2026;88:128770.
    PubMed         Abstract available
    
    
61. GONDWE KW, Hearst MO, Mbutuka HR, Khwepeya M, et al
    Factors associated with COVID-19 vaccine acceptance among refugee women at Dzaleka refugee camp in Malawi.
    Vaccine. 2026;88:128862.
    PubMed         Abstract available
    
    
62. LIU Z, Wang X, Hu Y, Duan X, et al
    Burden of infection and hospitalization from respiratory syncytial virus-associated acute lower respiratory tract infections in Chinese children: Modeling of national, regional, and provincial estimates.
    Vaccine. 2026;88:128875.
    PubMed         Abstract available
    
    
63. MORIO R, Takazono T, Morimoto S, Ashizawa N, et al
    Comparison of immunogenicity of mRNA and protein subunit SARS-CoV-2 vaccines in dialysis patients: a multicenter study.
    Vaccine. 2026;88:128861.
    PubMed         Abstract available
    
    
64. TORKAMAN-ASADI F, Bakhtiari S, Safarzadeh M, Riahi-Rad Z, et al
    Clinical outcomes among SARS-CoV-2 omicron-infected adults according to prior infection and vaccination history in Iran: A retrospective registry-based study.
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    PubMed         Abstract available
    
    
65. FLEMING JA, Colistro V, Knudson S, Colomar M, et al
    Timing and frequency of antenatal care visits in relation to maternal respiratory syncytial virus vaccine opportunities in four Latin American countries.
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    PubMed         Abstract available
    
    
66. ASAGA PM, Kroeger A, Yako A, Makpo J, et al
    Global misinformation, local consequences: conspiracy theory endorsement and a graded association with COVID-19 vaccine refusal across Nigeria.
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67. RICKE IJ, Ward C, Spaulding AB, Sherwood NE, et al
    Caregiver COVID-19 vaccine status and its influence on pediatric vaccination decisions in a US cohort.
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68. RAZZAGHI H, Garacci E, Kahn KE, Meghani M, et al
    Maternal and infant immunizations for respiratory diseases, United States, may 2025.
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    PubMed         Abstract available
    
    

    
    Virology

69. BYRNE AMP, James J, Thomas SS, Warren CJ, et al
    Impact of prior low-pathogenicity avian influenza H7N7 exposure on susceptibility and protection against homologous high-pathogenicity avian influenza H7N7 challenge in chickens.
    Virology. 2026;624:111047.
    PubMed         Abstract available
    

#Influenza and Other Respiratory Viruses Research #References (AMEDEO, August 9 '26)

 

Ann Intern Med

1. CHEN V, Glatt AE
   In older adults, mRNA-1010 vs. a licensed standard-dose influenza vaccine reduced influenza A- or B-related ILI at a median 181 d.
   Ann Intern Med. 2026 Aug 4. doi: 10.7326/ANNALS-26-02527.
   PubMed         Abstract available
   
   

   
   Antimicrob Agents Chemother

2. SUN Z, Huang Y, Guo R, Jiang T, et al
   Anti-RSV drug screening and inhibition of RSV infection by lapatinib through the IL-17 pathway.
   Antimicrob Agents Chemother. 2026;70:e0197225.
   PubMed         Abstract available
   
   
3. RODRIGUEZ L, Andreatta K, Chen S, Hu Y, et al
   Virologic insights from the phase 3 REDPINE trial: remdesivir in renally impaired and immunocompromised patients with COVID-19.
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   Antiviral Res

4. WANG K, Gibbons JS, Bisht N, Reyes AC, et al
   SARS-CoV-2 resistance pathways to EDP-235.
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   PubMed         Abstract available
   
   
5. WU R, Wang H, Yin R, Gemingnuer A, et al
   Nanoparticles in viral pneumonia: diagnosis, therapy, and prevention.
   Antiviral Res. 2026;253:106482.
   PubMed         Abstract available
   
   

   
   BMC Pediatr

6. CHEN H, Fan Y, Huang Y
   Epidemiological characteristics and seasonal dynamics of six respiratory pathogens in children: a 2-year retrospective cross-sectional study in Chengdu, China.
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   PubMed         Abstract available
   
   
7. AMPOFO K, Heller E, Platt-Koch A, Gesteland P, et al
   Burden of laboratory-confirmed RSV hospitalization in children <5 years-of-age; 2019-2022.
   BMC Pediatr. 2026;26:706.
   PubMed         Abstract available
   
   

   
   J Immunol

8. ACKLAND J, Barozi V, Penrice-Randal R, Hartley C, et al
   Identifying molecular signatures underpinning treatment responses to novel therapeutics influencing COVID-19 outcomes.
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9. SILVA JDC, Almeida C, Silva BMS, Bonfim BS, et al
   Elastase and myeloperoxidase participate in neutrophil extracellular trap release stimulated by SARS-CoV-2.
   J Immunol. 2026;215:vkaf313.
   PubMed         Abstract available
   
   

   
   J Infect Dis

10. SMITH D, Weir IR, Ramirez S, Coelho CH, et al
    Impact of COVID-19 Monoclonal Antibody Therapy on Subsequent Vaccine-elicited SARS-CoV-2 Immune Responses.
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11. PLATT AP, Callier V, Grazioli A, Hu Z, et al
    Association of Plasma Biomarkers of Immunothrombosis With Death in Patients With Coronavirus Disease 2019 on Extracorporeal Membrane Oxygenation.
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12. SANGIORGIO G, Chamberlin G, Castagnoli R, Wachter B, et al
    Immune-Based Cytokine Signatures of Prolonged Pandemic-Associated Chilblains.
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13. JAYAWARDENA I, Dean NE, Witrick B, Litwin AH, et al
    2024-2025 COVID-19 mRNA Vaccine Effectiveness against Severe Disease.
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14. ROSAS-SALAZAR C, Gebretsadik T, Chappell JD, Peebles RS Jr, et al
    Infant Infection With Respiratory Syncytial Virus Genotypes and Subsequent Childhood Asthma Risk.
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15. KACHIKIS A, Frivold C, Pike M, Reed JC, et al
    Comparison of Respiratory Syncytial Virus (RSV)-Specific Antibody Durability in Pregnant/Postpartum Individuals and Older Adults After RSV Vaccination.
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16. KOBERSSY Z, Daher J, Durieux JC, Atieh O, et al
    Comparison of Immune Activation and Gut Barrier Dysfunction between Long COVID and HIV infection.
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17. FEYS S, Heylen J, Goncalves SM, Pereira I, et al
    Genetic variation in the long pentraxin PTX3 and Dectin-1 does not predispose to influenza- or COVID-19-associated pulmonary aspergillosis.
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    PLoS One

18. ALSHAMMARI AO, Alshammari HO, Ali H, Himmat B, et al
    A flexible exponential type family for modeling non-monotonic hazard rates with application to mortality analysis: A COVID-19 case study.
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19. GOURAUD C, Guemouni S, Thoreux P, Ouazana-Vedrines C, et al
    Health-related quality of life among patients with long COVID according to the presence of a diagnosis of functional somatic disorder: A cross-sectional study.
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    Proc Natl Acad Sci U S A

20. ZHOU J, Li W, Wang X, Sun J, et al
    A structural and mechanistic atlas of NTD antibody neutralization and immune escape across SARS-CoV-2 prototype and its (sub-)variants.
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21. MULLER L, Sartori F, Dehning J, Eggl MF, et al
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    Vaccine

22. XU N, Wang L, Zhao C, Shen Y, et al
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#Influenza and Other Respiratory Viruses Research #References (AMEDEO, August 1 '26)

 

Arch Virol

1. LEE K, An SH, Heo GB, Lee YJ, et al
   Genomic characterization of H6N1 avian influenza viruses from wild birds and domestic ducks in the republic of Korea and Mongolia (2022-2024).
   Arch Virol. 2026;171:238.
   PubMed         Abstract available
   
   

   
   Biochem Soc Trans

2. MADDUMAGE JC, Dow GR, Murdolo LD, Liwei Leong S, et al
   Deciphering influenza B virus-derived peptides and their presentation by HLA class I molecules.
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Estimating the #infection #fatality #ratio of zoonotic avian #influenza viruses with #pandemic potential using an evolutionary epidemiological model

 

Abstract

The risk of zoonotic avian influenza (AIV) infection to humans is challenging to estimate as many human avian influenza virus infections are undetected because infections may be asymptomatic, symptomatic but not tested, and difficult to identify through contact tracing, as human-to-human transmission is rare. We derive equations that consider the evolutionary mechanisms that give rise to pandemics and are parameterized to be consistent with records of past pandemics. We estimate that thousands of human infections with AIVs possessing pandemic potential occur worldwide in an average year. Combining these estimates with H5N1 fatality data, we estimate a historical average infection fatality ratio of 32 (95% uncertainty interval: 9.6-75) deaths per 10,000 infections. This estimate is comparable to SARS-CoV-2 during the recent pandemic and higher than seasonal human influenza. We estimate that preventing animal-to-human influenza spillovers would delay pandemic emergence by several years. Preventing human infections with AIVs is necessary given the high risk of severe outcomes to individuals and to reduce the risk of pandemics occurring in the future.

Competing Interest Statement

The authors have declared no competing interest.

Source: 

Link: https://www.medrxiv.org/content/10.64898/2026.01.21.26344526v3

____

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#Influenza and Other Respiratory Viruses Research #References (AMEDEO, July 11 '26)

 

BMC Pediatr

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    Vaccine

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