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Showing posts from January 12, 2025

#Coronavirus Disease Research #References (by AMEDEO, January 12 '25)

  BMJ KAST KA, Sidelnik SA, Nejad SH, Suzuki J, et al Management of alcohol withdrawal syndromes in general hospital settings. BMJ. 2025;388:e080461. PubMed           Abstract available Clin Infect Dis XIANG W, Steinbeis F, Dhindsa K, Kurth F, et al Predicting the risk of intensive care unit admission in patients with COVID-19 presenting in the emergency room: Development and evaluation of the CROSS score. Clin Infect Dis. 2025 Jan 10:ciaf006. doi: 10.1093. PubMed           Abstract available Infect Control Hosp Epidemiol NAKASHITA M, Kurosawa K, Fukusumi M, Irie F, et al Improving the ability of psychiatric hospitals to respond to infectious disease outbreaks: lessons learned from the COVID-19 outbreak response in Ibaraki Prefecture, Japan. Infect Control Hosp Epidemiol. 2025 Jan 8:1-2. doi: 10.1017/ice.2024. PubMed          VAN REST A, Clarke A, Gounde...

#Influenza and Other Respiratory Viruses Research #References (by AMEDEO, January 12 '25)

  Arch Virol SAKUMA S, Mine J, Uchida Y, Kumagai A, et al Long-term immune responses induced by low-dose infection with high pathogenicity avian influenza viruses can protect mallards from reinfection with a heterologous strain. Arch Virol. 2025;170:33. PubMed           Abstract available ARVIA R, Rocca A, Casciato B, Stincarelli MA, et al High-resolution melting analysis for detection of nucleotide mutation markers in the polymerase-acidic (PA) gene of influenza virus that are associated with baloxavir marboxil resistance. Arch Virol. 2025;170:29. PubMed           Abstract available ASHRAF MA, Raza MA, Imran A, Amjad MN, et al Next-generation vaccines for influenza B virus: advancements and challenges. Arch Virol. 2025;170:25. PubMed           Abstract available REHMAN Z, Edington K, Jamal Z, Kritz-Wilson A, et al The introduction of the SARS-CoV-2...

Development of avian #influenza A(#H5) virus #datasets for #Nextclade enables rapid and accurate #clade assignment

Abstract The ongoing panzootic of highly pathogenic avian influenza (HPAI) A(H5) viruses is the largest in history , with unprecedented transmission to multiple mammalian species . Avian influenza A viruses of the H5 subtype circulate globally among birds and are classified into distinct clades based on their hemagglutinin (HA) genetic sequences. Thus, the ability to accurately and rapidly assign clades to newly sequenced isolates is key to surveillance and outbreak response . Co-circulation of endemic, low pathogenic avian influenza (LPAI) A(H5) lineages in North American and European wild birds necessitates the ability to rapidly and accurately distinguish between infections arising from these lineages and epizootic HPAI A(H5) viruses. However, currently available clade assignment tools are limited and often require command line expertise, hindering their utility for public health surveillance labs. To address this gap, we have developed datasets to enable A(H5) clade assignments wit...

Comprehensive #Infectome #Analysis Reveals Diverse Infectious Agents with #Zoonotic #Potential in #Wildlife

Abstract Understanding wildlife-pathogen interactions is crucial for mitigating zoonotic risk . Through meta-transcriptomic sequencing we profiled the infectomes of 1,922 samples from 67 mammalian species across China , uncovering a remarkable diversity of viral, bacterial, fungal, and parasitic pathogens. Of the 195 pathogens identified , 62 were novel , including a bi- segmented coronavirus in diseased lesser pandas, which we propose represents a new genus – Zetacoronavirus . The orders Carnivora and Rodentia exhibited the highest pathogen diversity and were implicated in numerous host-jumping events. Comparative analysis of diseased versus healthy animals revealed a trend of higher pathogen loads in the former, with possible differences in tissue tropisms. In total, 48 zoonotic and 17 epizootic pathogens were identified, with frequent cross-species transmission , emphasizing the potential for emerging public health threats. This study highlights the urgent need for wildlife pathogen...

The Channel of Gravelines, Petit Fort - Philippe Georges Seurat (1890)

 Source: WikiArt,  https://www.wikiart.org/en/georges-seurat/the-channel-of-gravelines-petit-fort-philippe-1890 Public Domain. _____