Abstract In an epidemiologic investigation of Enterovirus (EV) infections in a Verona hospital , September 2022–September 2024, we detected EV-C105 in six pediatric patients with upper respiratory symptoms between March and May 2023. The primary objective was to describe the local incidence of EV cases. The secondary objective was to perform Sanger’s genomic characterization and the whole-genome sequencing (WGS) of EV-C105. The proportion of positive EV results was calculated based on routine molecular method testing. An available cohort of 114 underwent Sanger sequencing, and the six EV-C105 were characterized with WGS. Overall, 96% EV results were from the upper respiratory tract . The total proportion of positives in children was 83%. Out of the typed 114, 90% were Rhinoviruses and 9%, EVs . Notably, six pediatric cases were EV-C105 , placing together in a unique cluster with 99% of nucleotides belonging to the European lineage with the highest Average Nucleotide Identity, including...
Media Monitoring for Signals about Emerging Threats