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#Cambodia reports 14th #human case of #H5N1 avian #influenza virus infection in 2025

PHNOM PENH, July 29 (Xinhua) -- A 26-year-old man from northwest Cambodia's Siem Reap province has been confirmed for H5N1 human avian influenza, raising the number of the cases to 14 so far this year, the Ministry of Health said in a statement on Tuesday. "A laboratory result from the National Institute of Public Health showed on July 26 that the man was positive for H5N1 virus," the statement said. "The patient has the symptoms of fever, cough, sore throat, stomach ache , and breathing difficulty, and is currently being rescued by a team of doctors," it added. The victim lives in Kravann village of Siem Reap city. "Investigations revealed that there were dead chickens near the patient's house and he also culled and plucked chickens three days before he fell ill," the statement said. Health authorities are looking into the source of the infection and are examining any suspected cases or people who have been in contact with the victim in order to p...

#Influenza at the #human - #animal #interface - #Summary and #risk #assessment, from 28 May to 1 July 2025 (#WHO)

  New human cases {2}:  -- From 28 May to 1 July 2025 , based on reporting date, the detection of influenza A( H5N1 ) in nine humans , influenza A( H9N2 ) in three humans and influenza A( H10N3 ) in one human were reported officially. Additionally, one human case of infection with an influenza A(H5N1) virus was detected.  Circulation of influenza viruses with zoonotic potential in animals :  -- High pathogenicity avian influenza (HPAI) events in poultry and non-poultry continue to be reported to the World Organisation for Animal Health (WOAH).{3} The Food and Agriculture Organization of the United Nations (FAO) also provides a global update on avian influenza viruses with pandemic potential.{4}  Risk assessment {5}:  -- Sustained human to human transmission has not been reported from these events.  -- Based on information available at the time of the risk assessment, the overall public health risk from currently known influenza viruses circulating at t...

Avian #Influenza A(#H5N1) - #Cambodia (#WHO D.O.N., July 5 '25)

  Situation at a glance Between 1 January and 1 July 2025, the World Health Organization (WHO) was notified by Cambodia’s International Health Regulations (IHR) National Focal Point (NFP) of 11 laboratory-confirmed cases of human infection with avian influenza A(H5N1) virus .  Seven of the 11 cases were reported in June , an unusual monthly increase .  Avian influenza A(H5N1) was first detected in Cambodia, in December 2003, initially affecting wild birds.  Since then, 83 cases of human infection with influenza A(H5N1), including 49 deaths (case fatality ratio [CFR] of 59%), have been reported in the country.  While the virus continued to circulate in avian species , no human cases were reported between 2014 and 2022, after which, the virus re-emerged in humans in February 2023.  Since the re-emergence of human A(H5N1) infections in Cambodia in 2023, a total of 27 cases have been reported (six in 2023, 10 in 2024, and 11 to date in 2025), of which 12 were f...

Little #boy in SW #Cambodia becomes 12th victim of #H5N1 #birdflu in 2025

  PHNOM PENH, July 3 (Xinhua) -- A five-year-old boy from southwest Cambodia's Kampot province has been confirmed for H5N1 human avian influenza, bringing the number of cases to 12 so far this year, the Ministry of Health said in a statement on Thursday. "A laboratory result from the National Institute of Public Health showed on July 3 that the boy was positive for H5N1 virus," the statement said. "The patient has the symptoms of fever, cough, and dyspnea , and he is currently being rescued by a team of doctors." The victim lives in Kamakor village of Angkor Chey district .  Source: Xinhua,  https://english.news.cn/asiapacific/20250703/a96b269ca29f41238c41884f8b390782/c.html ____

#Cambodia records 11th #human case of #H5N1 #birdflu in 2025

  PHNOM PENH, July 1 (Xinhua) -- A 36-year-old woman from northwest Cambodia's Siem Reap province has been confirmed for H5N1 human avian influenza, raising the number of the cases to 11 so far this year , the Ministry of Health said in a statement on Tuesday. "A laboratory result from the Pasteur Institute in Cambodia showed on June 30 that the woman was positive for H5N1 virus," the statement said. "The patient has the symptoms of fever, cough, and dyspnea , and she is currently being rescued by a team of doctors." The victim lives in Doun Keo village of Puok district. There were sick and dead chickens at the patient's home. She had been in contact with those dead chickens and took them to bury. Health authorities are looking into the source of the infection and are examining any suspected cases or people who have been in contact with the victim in order to prevent an outbreak in the community. Tamiflu (oseltamivir), an antiviral drug to prevent the bird f...

#Cambodia reported four additional #human cases of #infection with #influenza A #H5N1 virus during week 26/2025 (HK CPH, July 1 '25)

  {Excerpt} [Date of report - Country - Province / Region - District - City - Sex - Age - Condition at time of reporting  - Subtype of virus]  1) 24/06/2025 - Cambodia - Siem Reap province  - F - 41 - Critical  - H5N1  2) 29/06/2025 - Cambodia -  Siem Reap province  - F - 46 - Stable - H5N1  3) 29/06/2025 - Cambodia -  Siem Reap province  - M - 16 - Stable - H5N1  4) 30/06/2025 - Cambodia -  Takeo province - M - 19 months  - Deceased - H5N1  (...) Source: Centre for Health Protection, Hong Kong PRC SAR,  https://www.chp.gov.hk/files/pdf/2025_avian_influenza_report_vol21_wk26.pdf ____

{A family cluster of cases:} #Mother, #son contract #H5N1 #birdflu in #Cambodia

  PHNOM PENH, June 29 (Xinhua) -- A 46-year-old Cambodian mother and her 16-year-old son have been confirmed positive for H5N1 human avian influenza, bringing the total number of cases to 10 so far this year, the Ministry of Health said in a statement on Sunday. Both victims live in Lbeuk village of Puok district in northwest Siem Reap province. "According to queries, there were sick and dead poultry at the patients' home and their neighbors' homes as well as in the village, and the patients had been in contact with sick and dead chickens and cooked them for food," it added. Health authorities are looking into the source of the infection and are examining any suspected cases or people who have been in contact with the victims in order to prevent an outbreak in the community. Tamiflu (oseltamivir), an antiviral drug to prevent the bird flu from spreading, was also given out to people who had direct contact with the patients, the statement said. So far this year, the ki...

#Cambodia records 7th #human case of #H5N1 avian #influenza in 2025

  PHNOM PENH, June 24 (Xinhua) -- A 41-year-old woman from northwestern Cambodia's Siem Reap province has been confirmed for H5N1 human avian influenza, raising the number of cases to seven so far this year , the Ministry of Health said in a statement Monday night. "A laboratory result from the National Institute of Public Health showed on June 23 that the woman was positive for H5N1 virus," the statement said. "The patient has the symptoms of fever, cough, and dyspnea , and she is currently in critical condition ," it added. According to queries, there were sick and dead chickens at the patient's home and her neighbor's homes, and the patient had been in contact with sick and dead chickens and cooked them for food five days before she felt ill. Health authorities are looking into the source of the infection and are examining any suspected cases or people who have been in contact with the victim in order to prevent an outbreak in the community. Tamiflu (...

Man in #Cambodia dies of #H5N1 avian #influenza #H5N1

  PHNOM PENH, June 21 (Xinhua) -- A 52-year-old man from southeastern Cambodia's Svay Rieng province had died of H5N1 human avian influenza , becoming the fifth human death from the virus so far this year , the Ministry of Health said in a press statement on Saturday. "A laboratory result from the National Institute of Public Health showed on June 20 that the man was positive for H5N1 virus ," the statement said. Health authorities are looking into the source of the infection and are examining any suspected cases or people who have been in contact with the victim in order to prevent an outbreak in the community, it added. Tamiflu (oseltamivir), an antiviral drug to prevent the bird flu from spreading, was also given out to people who had direct contact with the patient, the statement said. The Southeast Asian country recorded a total of six human cases of H5N1 so far this year, with five deaths. Source: Xinhua,  https://english.news.cn/asiapacific/20250621/e94aafa92dbc446...

#Cambodia confirmed one additional #human #infection with #influenza A #H5N1 (Min. Health, June 17 '25)

{Automatic translation} The Ministry of Health of Cambodia notified a case of avian influenza A(H5N1) : the patient is a 65-years-old woman from Kraing Ampil, Takeo Province . The patient is now hospitalized in Intensive Care Unit . She developed fever, cough, shortness of breath, did not report contact with diseased birds. A Response Team is investigating actively, adopting prevention and control measures. The case has been confirmed by Pasteur Institute of Cambodia . (...) Despite investigations so far excluded direct contact with diseases or dead poultry, the patient's relatives own birds and more analysis are being conducted. The Rapid Response Team continues to investigate the outbreak with the cooperation of local health authorities to find possible source of infection among poultry and humans. Close contacts of the patient are being searched and will be offered the antiviral oseltamivir for post-exposure prophylaxis. (...) Source: Cambodia Ministry of Health,  https://moh.go...

#Cambodia's 4th #death of #H5N1 #birdflu recorded in 2025

PHNOM PENH, May 28 (Xinhua) -- An 11-year-old boy from western Cambodia's Kampong Speu province had died of H5N1 human avian influenza , becoming the fourth human death from the virus so far this year, the Ministry of Health said in a press statement released on Wednesday. "A laboratory result from the Pasteur Institute of Cambodia showed on May 27 , 2025, that the boy was positive for the H5N1 virus," the statement said. The ill-fated boy lived in Samraong Tong district's Srey Sampoung village. "According to queries , chickens and ducks near the patient's house had gotten sick and died subsequently a week before the boy fell ill," the statement said. Health authorities are looking into the source of the infection and examining any suspected cases or people who have been in contact with the victim in order to prevent an outbreak in the community, it added. The Southeast Asian country recorded a total of four human cases of H5N1 so far this year, with all...

Characterization and evolutionary #history of novel #SARS-CoV-2-related #viruses in #bats from #Cambodia

Abstract Circulating bat coronaviruses present a significant pandemic threat, yet our  understanding of  their genetic diversity and evolutionary dynamics remains limited.  Over 3 years, we sampled  1,462 bats in Cambodia’s Steung Treng province,  identifying extensive and diverse  coronaviruses co-circulation. Using  metatranscriptomic and amplicon sequencing, we  generated 33 complete  sarbecovirus genomes, revealing novel lineages that cluster into four  distinct  groups, each associated with different Rhinolophus bat species. Our analysis  highlights rapid migration and recombination of sarbecovirus lineages over  short distances  and timescales. Of note, the receptor-binding domains of two novel  viral groups exhibit high  similarity to SARS-CoV-2, and pseudovirus assays  confirmed the ability of this spike protein  to mediate entry into cells expressing  human ACE2, suggesting a potentia...

Young #boy in #Cambodia contracts #H5N1 #birdflu

PHNOM PENH, March 23 (Xinhua) -- A three-year-and-six-month boy from northeast Cambodia's Kratie province has been confirmed for H5N1 human avian influenza , raising the number of cases to three so far this year , said a Ministry of Health's statement on Sunday. The boy had been brought to the hospital in a critical condition with fever, cough, and dyspnea , it said, adding that he is receiving medical treatment with the utmost care from a team of doctors. "According to queries, the patient's family raised chickens and about five chickens had died , as some others were sick, and his family members cooked the dead poultry for food," the statement said. Health authorities are looking into the source of the infection and are examining any suspected cases or people who have been in contact with the patient in order to prevent an outbreak in the community, it added. Among the three human cases of H5N1 so far this year , two had died, and all patients reportedly had a h...

#Cambodia confirmed a #fatal pediatric case of #H5N1 avian #influenza virus infection

{Original text in Khmer} Ministry of Health Press Release A Fatal Case of #H5N1 #influenza in a 2-Year-7-Month-Old Child The Ministry of Health of the Kingdom of Cambodia wishes to inform the public that there are a  case of bird flu in a 2-year-old 7-month-old child has been confirmed positive for the influenza virus  H5N1 by the National Institute of Public Health on February 25, 2025. Location : Tangak Village, Romchek Commune, Preah Sdach District, Prey Veng Province. According to doctors , the child died on February 25, 2025 due to the parents  took the child to the hospital, when him developed a serious condition, including fever, cough, fatigue, and difficulty retreating. Severe breathing . According to the investigation, the patient's house has a family chicken farm and there are dead chickens.  About 15 of them were sick and the children were sleeping and playing in the basement near the chicken coop. The national and subnational emergency response teams of ...

Emergence of a Novel #Reassortant Clade 2.3.2.1c Avian #Influenza A #H5N1 Virus Associated with #Human Cases in #Cambodia

Abstract After nearly a decade without reported human A/H5N1 infections , Cambodia faced a sudden resurgence with 16 cases between February 2023 and August 2024, all caused by A/H5 clade 2.3.2.1c viruses . Fourteen cases involved a novel reassortant A/H5N1 virus with gene segments from both clade 2.3.2.1c and clade 2.3.4.4b viruses. The emergence of this novel genotype underscores the persistent and ongoing threat of avian influenza in Southeast Asia . This study details the timeline and genomic epidemiology of these infections and related poultry outbreaks in Cambodia. Source: MedRxIV,  https://www.medrxiv.org/content/10.1101/2024.11.04.24313747v2 _____

#Cambodia records 1st #human #death from #H5N1 in 2025

PHNOM PENH, Jan. 10 (Xinhua) -- A 28-year-old man from southeast Cambodia's Kampong Cham province died of H5N1 human avian influenza on Friday, becoming the first death in 2025, the Ministry of Health said in a press statement. "Laboratory results from the National Institute of Public Health showed on Jan. 9, 2025 that the man was positive for H5N1 virus," the statement said. "Although our team of doctors had provided him intensive care , the patient died on Jan. 10, 2025 due to his severe condition , with the symptoms of fever, cough, and dyspnea ," it added. The patient lived in village 22 in Chamkar Leu district's Chamkar Andoung commune. "According to queries , the patient raised and fed chicken , and he cooked sick chicken for food," the statement said. Health authorities are looking into the source of the infection and are examining any suspected cases or people who have been in contact with the victim in order to prevent an outbreak in the c...