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#Cambodia confirmed one additional #human #infection with #influenza A #H5N1 (Min. Health, June 17 '25)

{Automatic translation} The Ministry of Health of Cambodia notified a case of avian influenza A(H5N1) : the patient is a 65-years-old woman from Kraing Ampil, Takeo Province . The patient is now hospitalized in Intensive Care Unit . She developed fever, cough, shortness of breath, did not report contact with diseased birds. A Response Team is investigating actively, adopting prevention and control measures. The case has been confirmed by Pasteur Institute of Cambodia . (...) Despite investigations so far excluded direct contact with diseases or dead poultry, the patient's relatives own birds and more analysis are being conducted. The Rapid Response Team continues to investigate the outbreak with the cooperation of local health authorities to find possible source of infection among poultry and humans. Close contacts of the patient are being searched and will be offered the antiviral oseltamivir for post-exposure prophylaxis. (...) Source: Cambodia Ministry of Health,  https://moh.go...

#Cambodia's 4th #death of #H5N1 #birdflu recorded in 2025

PHNOM PENH, May 28 (Xinhua) -- An 11-year-old boy from western Cambodia's Kampong Speu province had died of H5N1 human avian influenza , becoming the fourth human death from the virus so far this year, the Ministry of Health said in a press statement released on Wednesday. "A laboratory result from the Pasteur Institute of Cambodia showed on May 27 , 2025, that the boy was positive for the H5N1 virus," the statement said. The ill-fated boy lived in Samraong Tong district's Srey Sampoung village. "According to queries , chickens and ducks near the patient's house had gotten sick and died subsequently a week before the boy fell ill," the statement said. Health authorities are looking into the source of the infection and examining any suspected cases or people who have been in contact with the victim in order to prevent an outbreak in the community, it added. The Southeast Asian country recorded a total of four human cases of H5N1 so far this year, with all...

Characterization and evolutionary #history of novel #SARS-CoV-2-related #viruses in #bats from #Cambodia

Abstract Circulating bat coronaviruses present a significant pandemic threat, yet our  understanding of  their genetic diversity and evolutionary dynamics remains limited.  Over 3 years, we sampled  1,462 bats in Cambodia’s Steung Treng province,  identifying extensive and diverse  coronaviruses co-circulation. Using  metatranscriptomic and amplicon sequencing, we  generated 33 complete  sarbecovirus genomes, revealing novel lineages that cluster into four  distinct  groups, each associated with different Rhinolophus bat species. Our analysis  highlights rapid migration and recombination of sarbecovirus lineages over  short distances  and timescales. Of note, the receptor-binding domains of two novel  viral groups exhibit high  similarity to SARS-CoV-2, and pseudovirus assays  confirmed the ability of this spike protein  to mediate entry into cells expressing  human ACE2, suggesting a potentia...

Young #boy in #Cambodia contracts #H5N1 #birdflu

PHNOM PENH, March 23 (Xinhua) -- A three-year-and-six-month boy from northeast Cambodia's Kratie province has been confirmed for H5N1 human avian influenza , raising the number of cases to three so far this year , said a Ministry of Health's statement on Sunday. The boy had been brought to the hospital in a critical condition with fever, cough, and dyspnea , it said, adding that he is receiving medical treatment with the utmost care from a team of doctors. "According to queries, the patient's family raised chickens and about five chickens had died , as some others were sick, and his family members cooked the dead poultry for food," the statement said. Health authorities are looking into the source of the infection and are examining any suspected cases or people who have been in contact with the patient in order to prevent an outbreak in the community, it added. Among the three human cases of H5N1 so far this year , two had died, and all patients reportedly had a h...

#Cambodia confirmed a #fatal pediatric case of #H5N1 avian #influenza virus infection

{Original text in Khmer} Ministry of Health Press Release A Fatal Case of #H5N1 #influenza in a 2-Year-7-Month-Old Child The Ministry of Health of the Kingdom of Cambodia wishes to inform the public that there are a  case of bird flu in a 2-year-old 7-month-old child has been confirmed positive for the influenza virus  H5N1 by the National Institute of Public Health on February 25, 2025. Location : Tangak Village, Romchek Commune, Preah Sdach District, Prey Veng Province. According to doctors , the child died on February 25, 2025 due to the parents  took the child to the hospital, when him developed a serious condition, including fever, cough, fatigue, and difficulty retreating. Severe breathing . According to the investigation, the patient's house has a family chicken farm and there are dead chickens.  About 15 of them were sick and the children were sleeping and playing in the basement near the chicken coop. The national and subnational emergency response teams of ...

Emergence of a Novel #Reassortant Clade 2.3.2.1c Avian #Influenza A #H5N1 Virus Associated with #Human Cases in #Cambodia

Abstract After nearly a decade without reported human A/H5N1 infections , Cambodia faced a sudden resurgence with 16 cases between February 2023 and August 2024, all caused by A/H5 clade 2.3.2.1c viruses . Fourteen cases involved a novel reassortant A/H5N1 virus with gene segments from both clade 2.3.2.1c and clade 2.3.4.4b viruses. The emergence of this novel genotype underscores the persistent and ongoing threat of avian influenza in Southeast Asia . This study details the timeline and genomic epidemiology of these infections and related poultry outbreaks in Cambodia. Source: MedRxIV,  https://www.medrxiv.org/content/10.1101/2024.11.04.24313747v2 _____

#Cambodia records 1st #human #death from #H5N1 in 2025

PHNOM PENH, Jan. 10 (Xinhua) -- A 28-year-old man from southeast Cambodia's Kampong Cham province died of H5N1 human avian influenza on Friday, becoming the first death in 2025, the Ministry of Health said in a press statement. "Laboratory results from the National Institute of Public Health showed on Jan. 9, 2025 that the man was positive for H5N1 virus," the statement said. "Although our team of doctors had provided him intensive care , the patient died on Jan. 10, 2025 due to his severe condition , with the symptoms of fever, cough, and dyspnea ," it added. The patient lived in village 22 in Chamkar Leu district's Chamkar Andoung commune. "According to queries , the patient raised and fed chicken , and he cooked sick chicken for food," the statement said. Health authorities are looking into the source of the infection and are examining any suspected cases or people who have been in contact with the victim in order to prevent an outbreak in the c...