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Genomic-based #biosurveillance for avian #influenza: whole genome sequencing from wild #mallards sampled during autumn migration in 2022–23 reveals a high co-infection rate on migration stopover site in #Georgia

  Abstract The Caucasus region, including Georgia, is an important intersection for migratory waterbirds , offering potential for avian influenza virus (AIV) transmission between populations from different geographic areas. In 2022 and 2023, wild ducks were sampled during autumn migration events in Georgia to study the genetic relationships and molecular characteristics of influenza strains. Sequencing and phylogenetic analysis were used to compare the sampled strains to reference sequences from Africa, Asia, and Europe , allowing assessment of genetic relationships and virus transmission between migratory birds. Protein language modeling identified potential co-infections. Of 225 duck samples, 128 tested positive for the influenza M gene . 55 influenza-positive samples underwent whole-genome sequencing, revealing significant diversity. Analysis of the hemagglutinin (HA) segment showed notable differences among subtypes. Most samples were H6N1 and H6N6 , but co-infections with comb...

#USA, Highly Pathogenic Avian #Influenza #H5N1 Confirmed in Commercial #Poultry Flock in #Georgia, All Poultry Activities Suspended

Atlanta, Ga – Today, the Georgia Department of Agriculture and the United States Department of Agriculture’s Animal and Plant Health Inspection Service confirmed a positive case of Highly Pathogenic Avian Influenza (HPAI) in a commercial poultry operation located in Elbert County, Georgia .  This is the first confirmed HPAI case in a commercial poultry operation in Georgia, and the fifth detection in the state of Georgia .  As a result of this detection , effective immediately, all in-state poultry exhibitions, shows, swaps, meets, and sales are suspended until further notice.   "For the first time since the ongoing, nationwide outbreak began in 2022, HPAI has been confirmed in a commercial poultry operation in the state of Georgia," said Georgia Agriculture Commissioner Tyler Harper.  "This is a serious threat to Georgia’s #1 industry and the livelihoods of thousands of Georgians who make their living in our state’s poultry industry. We are working around the c...