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#Germany, #Birdflu in #Brandenburg: #Cats infected with avian #influenza – warning from the district (Tagesspiegel, Dec. 4 '25)

{Excerpt} Several cats in Neuruppin have been infected with avian influenza , according to the Ostprignitz-Ruppin district administration . They have been taken into the care of the Office for Consumer Protection and Agriculture, the district announced. A cat infected with the H5N1 strain of the avian influenza virus was found dead in a wooded area near the town. Several media outlets have reported on this.  (...) Source:  Link:  https://www.tagesspiegel.de/berlin/vogelgrippe-in-brandenburg-katzen-mit-geflugelpest-infiziert--warnung-vom-kreis-15014940.html ____

#Mammalian #adaptation and zoonotic #risk of #influenza A viruses in companion #animals

  Abstract Importance Since the early 2000s, companion animals emerged as unexpected players in influenza A virus ecology . Canine influenza viruses and the increasing detection of highly pathogenic avian influenza viruses in cats have raised concerns about their potential role as intermediate hosts for pandemic emergence . Their unique position at human-animal interface creates unprecedented opportunities for viral evolution and bidirectional transmission between humans and animals. Observations This review examined the transmission pathways and molecular adaptations of influenza A virus in companion animals. Cats primarily acquire infections through alimentary routes , including consumption of raw poultry and unpasteurized milk , as well as environmental exposure through hunting. Dogs transmit influenza viruses via respiratory droplets in high-density settings such as shelters and kennels . Canine influenza viruses demonstrate successful mammalian adaptation through accumulated m...

The #Netherlands confirms its first #death from avian #influenza #H5N1 in a #cat (Xinhua, Dec. 3 '25)

  The Hague, December 2 (Xinhua)  Dutch Minister of Agriculture, Fisheries, Food Safety and Nature, Femke Wilsma, reported on December 1 that the country had confirmed its first death from the H5N1 highly pathogenic avian influenza virus . In a letter to the House of Representatives that day, Wilsma stated that the Institute of Biological Veterinary Medicine at Wageningen University had recently reported that a kitten at a goat farm tested positive for the highly pathogenic H5N1 avian influenza virus .  The kitten was found dead by its owner.  The remaining seven kittens from the same litter also died after being given to other new owners, suggesting that they may have also been infected with the avian influenza virus, but the specific route of infection is still uncertain. The letter stated that, according to the cat owner, the mother cat had brought back a dead wild bird , which was suspected to have carried the avian influenza virus, and the kittens were infected ...

Highly Pathogenic Avian #Influenza #H5N1 in Raw #Pet #Foods and #Milk: A Growing #Threat to both Companion Animals and #Human #Health, and Potential Raw Pet Food Industry Liability

  Highlights •  Raw pet foods and raw milk are emerging sources of H5N1 in pets . •  Cats are more severely infected with H5N1 when compared to dogs. •  H5N1 persistence in mammals indicate adaptive variants with increased zoonotic potential. •  No reported pet-to-human transmission of H5N1 has been reported. •  FDA now requires RMBD makers who are covered under FSMA to assess HPAI risk. Abstract The increasing popularity of raw meat-based diets (RMBDs) and raw milk feeding in companion animals presents a growing concern for zoonotic disease transmission. Recent evidence has demonstrated that these products can serve as vehicles for highly pathogenic avian influenza (HPAI) H5N1 , an emergent viral threat with a host range from birds, dairy cattle , and pets to humans . Since the emergence of clade 2.3.4.4b in 2020 , HPAI H5N1 has caused widespread outbreaks in poultry, wild birds, and mammals , including dairy cattle and cats . Transmission to pets has been...

Companion #animals and #H5N1 highly pathogenic avian #influenza: cause for #concern?

Abstract The first known human infection with a highly pathogenic H5N1 influenza A virus appeared in China in 1997 . Between 2003 and 2017, the WHO documented an additional 862 human cases, mainly from southeast Asia and Egypt , with a mean annual case fatality rate of 56%. By 2006, the susceptibility of cats to severe respiratory and neurologic disease became apparent. Scientists raised concerns regarding the potential for domestic cats to transmit novel pathogenic strains to humans. But after 2006, reports of new H5N1 infections in companion animals dwindled, and human cases fell after 2016. In 2021, H5N1 clade 2.3.4.4b viruses suddenly appeared in Europe and spread rapidly to the Americas , wreaking havoc on wildlife and crippling the poultry and dairy industries . Between 2022 and 2025, dozens of domestic cats died , most often following raw food consumption . Unease regarding the transmission potential of pets resurfaced. Although most human infections in the Americas were mild an...

Updated joint #FAO / #WHO / #WOAH public #health #assessment of recent #influenza #H5 virus #events in animals and people (July 28 '25)

  Key points   -- At the present time , based on available information, FAO-WHO-WOAH assess the global public health risk of influenza A(H5) viruses to be low , while the risk of infection for occupationally or frequently exposed (e.g., with backyard poultry) persons is low to moderate depending on the risk mitigation and hygiene measures in place and the local avian influenza epidemiological situation.  -- Transmission between animals continues to occur and, to date, a growing yet still limited number of human infections are being reported. Although additional human infections associated with exposure to infected animals or contaminated environments are expected to occur, the overall public health impact of such infections at a global level , at the present time, is considered minor . The assessment could change if and when additional epidemiological or virological information becomes available.  -- This risk assessment from FAO, WHO and WOAH updates the assessment ...

#Influenza D Virus in Domestic and Stray #Cats, Northern #China, 2024

Abstract Influenza D virus infects primarily cattle , but infrequent reports of infections in cats occur. We detected influenza D virus antibodies in 8 of 360 cats in northern China . Domestic cats showed higher susceptibility than strays. Our results suggest a previously overlooked aspect of epidemiology of this virus in companion animals. Source: US Centers for Disease Control and Prevention,  https://wwwnc.cdc.gov/eid/article/31/8/25-0042_article ____

Notes from the Field: Early-Season #Human #Plague Transmitted from an Infected #Cat — #Oregon, January 2024

  Summary -- What is known about this topic? -  Plague is caused by the bacterium Yersinia pestis , which is transmitted primarily through fleas from rodents . This case highlights an off-season transmission of plague. Plague is most often identified during May–August. -- What is added by this report? - An Oregon man sought care at an emergency department for signs and symptoms of plague on January 30, 2024, the earliest calendar date of plague recorded in the state’s history, possibly indicating a shift in the seasonality of plague incidence . The patient did not have direct contact with rodents, but did have contact with his infected cat after cutting his finger. -- What are the implications for public health practice? -  Public health messaging and diagnostic efforts regarding plague are warranted year-round in areas with endemic disease. Abstract Plague is caused by the bacterium Yersinia pestis . Y. pestis is transmitted primarily through the bite of an infected rode...

Isolation of Highly Pathogenic Avian #Influenza #H5N1 Virus from #Cat #Urine after Raw #Milk Ingestion, #USA

Abstract In 2024, 3 domestic cats in California, USA consumed raw milk contaminated with highly pathogenic avian influenza A( H5N1 ) virus. Fever and neurologic signs developed; 2 cats died. The surviving cat’s urine tested positive for H5N1 virus by reverse transcription PCR. Raw dairy products pose a risk to both animal and human health. Source: US Centers for Disease Control and Prevention,  https://wwwnc.cdc.gov/eid/article/31/8/25-0309_article ____

The #Seroprevalence of #Influenza A Virus #Infections in Polish #Cats During a Feline #H5N1 Influenza #Outbreak in 2023

Abstract Recently, cats have emerged as potential incidental hosts for avian and human influenza A viruses (IAVs), including the highly pathogenic avian influenza (HPAI) H5N1 virus. Following an unprecedented outbreak of H5N1 HPAI in cats in Poland in June 2023, we conducted a cross-sectional epidemiological study to assess the seroprevalence of IAV, especially H5Nx , infections in domestic cats. Eight hundred thirty-five serum samples collected in June 2023 were tested using a competitive ELISA for antibodies to IAV nucleoprotein. Positive or doubtful samples were further screened for H5-specific antibodies. The overall seropositivity for IAV was 8.5% (CI 95%: 6.8%, 10.6%; 71/835 cats), and 23/68 IAV-seropositive cats (33.8%) were also seropositive for H5 antigen . Multivariable analysis identified young age (≤8 years) and male sex as significant risk factors for H5 seropositivity, while non-H5-IAV seropositivity was more common in cats aged ≥12 years. These findings suggest different...

The #OneHealth challenges and opportunities of the #H5N1 #outbreak in dairy #cattle in the #USA

ABSTRACT The outbreak of H5N1 in dairy cattle in United States revealed challenges in identification and management of a novel disease . The virus showed an exceptional ability to spread between farms and among cows within a farm. The impact of the virus on dairy cattle varied from nonclinical to severe clinical signs and death. Many dairy producers did not report clinical signs in their cows or test for the virus. Cats and peridomestic birds on many affected dairies died from viral exposure . Dairy workers showed signs of conjunctivitis , which was confirmed to be due to H5N1. With the disease affecting multiple species and showing efficient cow-to-cow transmission , the situation only worsened. There was a negative impact on the relationships among dairy producers, dairy workers, poultry producers, and veterinarians, in which professional and personal relationships were severed and some experienced loss of employment. The regulatory response varied by geographic location, and in some...

#USA, #NJ: #H5N1 Highly Pathogenic Avian #Influenza Confirmed in New Jersey Cats {DoH}

TRENTON, NJ - The first feline case of H5 Highly Pathogenic Avian Influenza (HPAI or “bird flu”) in New Jersey has been confirmed in a feral cat from Hunterdon County .  The case was confirmed by the United States Department of Agriculture (USDA) National Veterinary Services Laboratory, and follows previous national reports of confirmed feline cases in other states.   The cat developed severe disease, including neurologic signs , and was humanely euthanized.  Other cats on the same property were also reported ill , and one additional indoor-outdoor cat was subsequently confirmed positive for H5 HPAI. Other tests are still pending, and the investigation is ongoing. The overall public health risk remains low at this time. While H5 HPAI has been detected in humans in the U.S. – primarily in individuals with close contact with infected poultry or dairy cattle – there have been no human cases reported in New Jersey, and none of the cases across the country are known to h...

Highly Pathogenic Avian #Influenza A (#H5N1) Clade 2.3.2.1a virus #infection in domestic #cats, #India, 2025

Abstract In January 2025, the highly pathogenic avian influenza A(H5N1) virus clade 2.3.2.1a infection was detected in domestic cats and whole-genome sequencing of two cat H5N1 isolates was performed using the Oxford Nanopore MinION sequencing platform. Phylogenetic analysis revealed the circulation of triple reassortant viruses in cats. Although cat viruses lacked classic mammalian adaptation markers they carried mutations associated with enhanced polymerase activity in mammalian cells and increased affinity for α2-6 sialic acid receptor suggesting their potential role in facilitating infection in cats. The identification of reassortant HPAI H5N1 clade 2.3.2.1a viruses in domestic cats in India highlights the urgent need for enhanced surveillance in domestic poultry, wild birds, and mammals, including humans, to track genomic diversity and molecular evolution of circulating strains. Source: BioRxIV,  https://www.biorxiv.org/content/10.1101/2025.02.23.638954v1 ____