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#Nipah virus infection - #India (#WHO D.O.N., Jan. 30 '26)

  Situation at a glance On 26 January 2026, the National IHR Focal Point for India notified WHO of two laboratory‑confirmed cases of Nipah virus (NiV) infection in West Bengal State .  Both are healthcare workers at the same private hospital in Barasat (North 24 Parganas district).  NiV infection was confirmed at the National Institute of Virology in Pune on 13 January.  One case remains on mechanical ventilation as of 21 January, the other case experienced severe neurological illness but has since improved.  Authorities have identified and tested over 190 contacts , who all tested negative for NiV with support from a mobile BSL‑3 laboratory deployed by the National Institute of Virology, Pune.  No further cases have been detected to date.  This event represents the third NiV infection outbreak reported in West Bengal (previous outbreaks reported in Siliguri in 2001 and Nadia in 2007).  Enhanced surveillance and infection prevention and control (I...

#Pathology of dose dependent inocula of #H5N8 avian #influenza viruses in experimentally infected #chicken

  Abstract In the present study, we assessed the pathogenicity of H5N8 avian influenza viruses belongs to the clade 2.3.4.4b in chicken. Birds of three different dose groups, 10 2 , 10 4 , and 10 6 EID 50 were used in the study. No mortality was observed in 10 2 EID0 group. Percent cumulative mortality of 10 4 and 10 6 EID 50 group was 66.67 and 100 %, respectively. Varying duration of MDT of 3.2 and 2 days was observed in 10 4 and 10 6 EID 50 group, respectively. The CID 50 of virus was found to be 10 4.5 EID 50 . High no. of viral RNA copies were found both in oropharyngeal and cloacal swabs and in various organs of birds infected in 10 4 and 10 6 EID 50 group. Significant gross and histological changes and presence of viral antigen in various organs were observed in 10 4 and 10 6 EID 50 group. So, the study concludes that Indian HPAI, H5N8 isolates are highly pathogenic in nature to chicken by affecting most organs systemically. CID 50 of this H5N8 virus indicates poor adaption ...

#HK, DH follows up on #Nipah virus #infection cluster in #India (Jan. 26 '26)

  DH follows up on Nipah virus infection cluster in India In light of reports indicating a cluster of a Nipah virus infection in a certain region of India, the Centre for Health Protection (CHP) of the Department of Health (DH) said today (January 26) that it has proactively sought further information from the World Health Organization (WHO) and Indian health authorities .  The CHP is also conducting health screenings on inbound travellers from the affected area who exhibit suspected symptoms, with an aim of promptly referring suspected cases to hospitals for investigation.  Currently, there are no imported or local cases of Nipah virus infection in Hong Kong. Preliminary information indicated that a hospital in Kolkata, West Bengal, India, has recorded five confirmed cases of Nipah virus infection since mid-January of this year.  The cluster was mainly due to nosocomial transmission and primarily involved healthcare workers , with no reported deaths or cross-border ...

#India - High pathogenicity avian #influenza #H5N1 viruses (Inf. with) (#poultry) - Immediate notification

  {Kerala} 1) The outbreak was detected in ducks within an integrated rice–duck farming system. 2) The outbreak was detected in ducks within an integrated rice–duck farming system. 3) The outbreak was detected in ducks within an integrated rice–duck farming system. 4) The outbreak was detected in ducks within an integrated rice–duck farming system. 5) The outbreak was detected in ducks within an integrated rice–duck farming system. 6) The outbreak was detected in ducks within an integrated rice–duck farming system. 7) The outbreak was detected in ducks within an integrated rice–duck farming system. 8, 9 & 10) Poultry farms. Source:  Link:  https://wahis.woah.org/#/in-review/7161 ____

#India - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

Farmed and  Backyard poultry in Uttarakhand State. Source:  Link:  https://wahis.woah.org/#/in-review/6804 ____

#Kyasanur Forest #disease: an emerging #arboviral #threat

  Summary Kyasanur Forest disease is a neglected tick-borne viral haemorrhagic fever endemic to India's Western Ghats , caused by the Kyasanur Forest disease virus , a flavivirus transmitted by Haemaphysalis spinigera ticks . The virus circulates in a sylvatic cycle among monkeys, rodents, shrews, birds, and ixodid ticks , and is transmitted to humans incidentally via tick bites . Since its discovery in 1957 in Karnataka , Kyasanur Forest disease has spread to other Indian states, driven by deforestation , forest fragmentation , and increased human incursion into wildlife habitats . Clinically, the disease manifests in a biphasic pattern , with haemorrhagic and neurotropic presentations . Although a formalin-inactivated vaccine is available , its efficacy is not promising, and no antivirals have been approved to date. Field reports indicate that mortality in monkeys might serve as an early indicator of forthcoming human outbreaks. The transmission dynamics of Kyasanur Forest diseas...

#India - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

{Several poultry farms in Uttar Pradesh State.} HPAI (H5N1) was detected in a Live Bird Market from the environmental sample. Hence no cases were observed. Source: WOAH,  https://wahis.woah.org/#/in-review/6730 ____

#India - #Influenza A #H5N1 viruses of high pathogenicity (Inf. with) (non-poultry including wild birds) (2017-) - Immediate notification

  {By Charles J. Sharp - Own work, from Sharp Photography, sharpphotography.co.uk, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=116380120 } Nineteen captive Painted Storks in the National Zoological Park, Delhi. Source: WOAH,  https://wahis.woah.org/#/in-review/6803 ____

#India - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

  Two Poultry Farms in the Odisha State. Source: WOAH,  https://wahis.woah.org/#/in-review/6694 ____

#Nipah virus #infection - #India (#WHO D.O.N., August 6 '25)

Situation at a glance Between 17 May and 12 July 2025, the Information and Public Relations Department, Government of Kerala informed through a series of official press releases about four confirmed cases , including two deaths , due to Nipah virus (NiV) infection in two districts of Kerala State.  NiV infection is a bat-borne disease transmitted to humans through infected animals (such as bats or pigs), contaminated food or, less commonly, through close contact with infected individuals.  Since 1998 NiV outbreaks have been reported in Bangladesh, India, Malaysia , the Philippines , and Singapore .  In India, NiV infections have occurred multiple times since 2001 with outbreaks in West Bengal State in 2001 and 2007, and in Kerala State regularly since 2018.  Since 2018, Kerala has reported a total of nine NiV outbreaks . While the state has a strong healthcare system and improved infection control measures since 2023, it is advisable to maintain strong preparedness a...

#H1N1-associated acute #leukoencephalopathy: An unusual presentation in a young adult indian male

Abstract The H1N1 virus commonly causes symptoms such as fever, cough, sore throat, which have a self-limited course in most cases . Neurological complications are rare, especially in adults. This case illustrates H1N1-associated acute leukoencephalopathy in a young adult with a favorable outcome and no lasting neurological deficits . The initial presentation included fever, sore throat, and myalgia , evolving into neurological symptoms , including dysarthria, nystagmus, and left-sided motor weakness . Comprehensive laboratory tests ruled out common bacterial, viral, or autoimmune causes, while MRI findings suggested acute leukoencephalopathy of infectious or toxic etiology. Although the urine toxicology screen showed traces of phenol , clinical evidence did not correlate with toxic exposure and pointed towards an infectious origin. A throat swab for Influenza/H1N1 PCR confirmed the diagnosis. Treatment with oseltamivir and methylprednisolone led to symptomatic improvement with no sequ...

#Influenza at the #human - #animal #interface - #Summary and #risk #assessment, from 28 May to 1 July 2025 (#WHO)

  New human cases {2}:  -- From 28 May to 1 July 2025 , based on reporting date, the detection of influenza A( H5N1 ) in nine humans , influenza A( H9N2 ) in three humans and influenza A( H10N3 ) in one human were reported officially. Additionally, one human case of infection with an influenza A(H5N1) virus was detected.  Circulation of influenza viruses with zoonotic potential in animals :  -- High pathogenicity avian influenza (HPAI) events in poultry and non-poultry continue to be reported to the World Organisation for Animal Health (WOAH).{3} The Food and Agriculture Organization of the United Nations (FAO) also provides a global update on avian influenza viruses with pandemic potential.{4}  Risk assessment {5}:  -- Sustained human to human transmission has not been reported from these events.  -- Based on information available at the time of the risk assessment, the overall public health risk from currently known influenza viruses circulating at t...