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#Outbreak Reports: Epidemiological and Genetic Characterization of Three #H9N2 Viruses Causing #Human #Infections — Changsha City, #Hunan Province, #China, April 2025

  Summary -- What is already known about this topic? - A total of 117 H9N2 cases of human infection of Chinese origin had been reported to the World Health Organization (WHO) by May 9, 2025, with 22 of them originating in Hunan Province. -- What is added by this report? - This article reported on the investigation of three new H9N2 avian influenza virus (AIV) infections detected in Changsha, Hunan Province , in April 2025. No epidemiological link was found among them. Exposure to live poultry was identified as the primary risk factor for infection. Sequence analysis of the three H9N2 AIVs showed a similarity of 99.71%–99.82% between hemagglutinin (HA), and the homology of the neuraminidase (NA) genes was 98.41%–99.83%. Although the tests showed that the HA had enhanced binding ability to upper respiratory tract cells’ receptors , no evidence of sustained human-to-human transmission has been found so far. -- What are the implications for public health practice? - This study indicate...

#China notified two additional #human cases of infection with #influenza A #H9N2 (HK CHP, October, 14 '25)

  {Excerpt} Influenza A H9N2 -- Hunan Province : - 1) A two-year-old boy with onset on September 28, 2025.  -- Jiangxi Province : - 2) A 70-year-old woman with onset on September 23, 2025.  (...) Source: Centre for Health Protection, Hong Kong PRC SAR,  https://www.chp.gov.hk/files/pdf/2025_avian_influenza_report_vol21_wk41.pdf ____

#China reported four additional #human pediatric cases of #infection with avian #influenza #H9N2 virus (HK CHP, September 9 '25)

{Summary, excerpts} -- Avian influenza A(H9N2) :  - Anhui Province :  1) A two-year-old boy with onset on August 5, 2025.  - Chongqing Municipality :  2) A six-year-old boy with onset on July 30, 2025.  - Hunan Province 3) A two-year-old boy with onset on August 21, 2025.  - Sichuan Province :  4) A one-year-old boy with onset on July 28, 2025.  (...) Source: Centre for Health Protection, Hong Kong PRC SAR,  https://www.chp.gov.hk/files/pdf/2025_avian_influenza_report_vol21_wk36.pdf ____

#China reported three new #human cases of #infection with #H9N2 #influenza and one case of #H10N3 virus (#HK CHP, June 24 '25)

{Excerpt} Epi-Week 25 2025 Avian influenza A(H9N2) :  - Henan Province :  -- 1) A 52-year-old woman with onset on May 10, 2025.  - Hunan Province :  -- 2) A 72-year-old woman with onset on May 14, 2025.  - Sichuan Province :  --3) A six-year-old boy with onset on May 14, 2025. Avian influenza A(H10N3) :  - Shaanxi Province :  -- 1) A 70-year-old woman with onset on April 21, 2025.  (...) Source: Centre for Health Protection, Hong Kong PRC SAR,  https://www.chp.gov.hk/files/pdf/2025_avian_influenza_report_vol21_wk25.pdf ____

#China reported two additional #human infection with avian #influenza virus A #H9N2 (HK CHP, Feb. 11 '25)

 {Excerpt} Avian Influenza Report - VOLUME 21, NUMBER 6 - Reporting period: Feb 2, 2025 – Feb 8, 2025 (Week 6), (Published on February 11, 2025)  -- Mainland China: 2 new cases (0 death cases):  - Avian influenza A(H9N2) :  - Hunan Province :  - 1) A two-year-old boy with onset on December 27, 2024.   - 2) A 15-year-old boy with onset on January 8, 2025.  (...) Source: Centre for Health Protection, Hong Kong PRC SAR,  https://www.chp.gov.hk/files/pdf/2025_avian_influenza_report_vol21_wk06.pdf _____