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#USA, #Influenza A #H5N1 in #Humans: #Epidemiology & #Laboratory #Update {as of Feb. 26 '25}

{Excerpts} (...) Epidemiology Updates As of February 24, CDC has confirmed three human cases of H5 bird flu in people who became ill in 2025:  -- a dairy worker with exposure to infected dairy cows (Nevada),  -- a poultry worker with exposure to infected commercial poultry ( Ohio ), and  -- the owner of an infected backyard poultry flock ( Wyoming ).  These are all considered higher-risk exposures . While the dairy worker was not hospitalized , both people with poultry exposures experienced severe illness and were hospitalized . Both hospitalized cases were confirmed positive from lower respiratory specimens , including a bronchoalveolar lavage and sputum . To date, there has been no evidence of onward spread from any of these people to anyone else . The dairy worker in Nevada had conjunctivitis (eye redness and irritation) and has recovered . Most infections associated with U.S. dairy cows to date have involved mild respiratory symptoms or conjunctivitis. This perso...

#USA, Confirmed #human #H5N1 #influenza virus case #summary since 2024, by state and exposure source: One new case in #Nevada (Feb. 10 '25)

{Excerpt} [ State - Exposure Source: Exposure Associated with Commercial Agriculture and Related Operations: Dairy Herds (Cattle) - Poultry Farms and Culling Operations - Other Animal Exposure† - Exposure Source Unknown‡ - State Total ] 1) California -  36 - 0 - 0 - 2 -  38 2) Colorado -  1 - 9 - 0 - 0 -  10 3) Iowa -  0 - 1 - 0 - 0 -  1 4) Louisiana -  0 - 0 - 1 - 0 -  1 5) Michigan -  2 - 0 - 0 - 0 -  2 6) Missouri -  0 - 0 - 0 - 1 -  1 7) Nevada -  1 - 0 - 0 - 0 - 1 {+1} 8) Oregon -  0 - 1 - 0 - 0 -  1 9) Texas -  1 - 0 - 0 - 0 -  1 10) Washington -  0 - 11 - 0 - 0 -  11 11) Wisconsin -  0 - 1 - 0 - 0 -  1 -- Source Total -  41 - 23 - 1 - 3 -  68 {+1} NOTE : One additional case was previ...

#USA, APHIS Confirms {Avian #Influenza #H5N1} #D11 #Genotype in Dairy #Cattle in #Nevada

On January 31, 2025, the USDA Animal and Plant Health Inspection Service (APHIS) National Veterinary Services Laboratories (NVSL) confirmed by whole genome sequence the first detection of highly pathogenic avian influenza (HPAI) H5N1 clade 2.3.4.4b, genotype D1.1 in dairy cattle .  This confirmation was a result of State tracing and investigation, following an initial detection on silo testing under the USDA’s National Milk Testing Strategy (NMTS) in Nevada.  USDA APHIS continues to work with the Nevada Department of Agriculture by conducting additional on-farm investigation, testing, and gathering additional epidemiological information to better understand this detection and limit further disease spread.  This is the first detection of this virus genotype in dairy cattle (all previous detections in dairy cattle have been HPAI H5N1 clade 2.3.4.4b, genotype B3.13 ).  Genotype D1.1 represents the predominant genotype in the North American flyways this past fall an...