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Showing posts with the label flavivirus

#Zika virus disease - #India

Situation at a glance Between 1 January and 31 December 2024, a cumulative total of 151 Zika virus disease (ZVD) cases were reported from three states in India ( Gujarat, Karnataka, and Maharashtra states). Maharashtra State reported a cumulative total of 140 ZVD cases through the Integrated Disease Surveillance Programme (IDSP). Additionally, Karnataka and Gujarat states reported ten and one cases , respectively, in 2024. As of 31 December 2024, no cases of microcephaly and/or Guillain-Barre syndrome (GBS) associated with this outbreak have been reported. Zika virus (ZIKV) is transmitted to humans by the bite of an infected Aedes mosquito . Zika virus is also transmitted from mother to fetus during pregnancy, as well as through sexual contact, transfusion of blood and blood products, and possibly through organ transplantation. There is no specific treatment available for Zika virus infection or disease. Description of the situation Between 1 January and 31 December 2024, a cumulative ...

#Bussuquara Virus: A Neglected #Orthoflavivirus with Broad Distribution Across Central and South #America and the #Caribbean

Abstract Bussuquara virus (BSQV) was first discovered in the Brazilian Amazon in 1956 . It is an arthropod-borne virus (arbovirus) in the genus Orthoflavivirus , family Flaviviridae . Since its discovery, BSQV has been sporadically detected across the South ( Brazil, Columbia, and Argentina ) and Central ( Panama and Mexico ) America and the Caribbean ( Grenada ), but there is minimal BSQV surveillance due to limited public health awareness and a lack of specific or sensitive diagnostics. BSQV exposure has been reported in a wide range of host and vector species , including humans . Little information is available in the literature and herein we summarize the published historical findings on BSQV and suggest a pathway for future studies to better understand its potential emergence into human populations. Source: Viruses,  https://www.mdpi.com/1999-4915/17/2/183 _____

#Neurotropic #Tick-Borne #Flavivirus in Alpine #Chamois (Rupicapra rupicapra rupicapra), #Austria, 2017, #Italy, 2023

Abstract The European subtype of tick-borne encephalitis virus (TBEV-Eur; species Orthoflavivirus encephalitidis , family Flaviviridae ) was the only tick-borne flavivirus present in central Europe known to cause neurologic disease in humans and several animal species . Here, we report a tick-borne flavivirus isolated from Alpine chamois (Rupicapra rupicapra rupicapra) with encephalitis and attached ticks , present over a wide area in the Alps . Cases were detected in 2017 in Salzburg, Austria , and 2023 in Lombardy and Piedmont, Italy . The virus strains exhibit 94.8–97.3% nucleotide identities to each other and are more closely related to Louping ill viruses (LIV; Orthoflavivirus loupingi ; 90–92% identities) than to TBEV-Eur (less than 88%). The chamois-derived virus strains, tentatively termed “ Alpine chamois encephalitis virus ”, form a well-supported independent genetic clade with Spanish goat encephalitis virus , clearly separated from other LIV. This supports its designation a...