ETIDIOH - NEW

Highlights •  First isolation and molecular evidence of the subtype H3N2 in swine in Colombia . •  Swine H3N2 discovered is phylogenetically divergent from other viruses. •  Colombian H3N2 was originated from an independent human-to-swine spillover. •  Sequence-based analysis reveals this is a novel antigenic variant . •  Due to antigenic variation , Colombian H3N2 possess a relevant zoonotic risk. Abstract Influenza A virus (FLUAV) affects a wide range of hosts, including humans and animals, posing a threat to public health . In swine, H3N2 subtype is associated with human-to-swine spillovers of seasonal viruses . In Latin America , the molecular and antigenic characteristics of swine FLUAV H3N2, as well as its phylogenetic origin, are poorly understood. Therefore, the objective of this study was to characterize the first swine H3N2 detected in Colombia . The origin and lineage of the virus were estimated through phylogenetic and molecular clock analyses . Anti...

Abstract Influenza viruses are highly capable of mutating and adapting in mammalian hosts . While these viruses have been extensively studied in birds, research on their presence in bats has been limited. However, influenza viruses circulating in bats have shown notable molecular divergence . The present study aimed to characterize the phylogenetic, evolutionary, and antigenic relationships of an influenza A virus detected in the fishing bat Noctilio albiventris . As part of a pathogen surveillance study of public health interest, 159 rectal samples were collected from bats in the Colombian Caribbean . The samples were sequenced using RNA-Seq. A genome (eight viral contigs) associated with the Orthomyxoviridae family was identified in a pool. Most segments showed approximately 90% similarity with H18N11, except for the neuraminidase. Analysis of the N protein shows that occupies a basal position relative to the N11 subtype, with its divergence date estimated to be approximately 50 year...

Abstract Bussuquara virus (BSQV) was first discovered in the Brazilian Amazon in 1956 . It is an arthropod-borne virus (arbovirus) in the genus Orthoflavivirus , family Flaviviridae . Since its discovery, BSQV has been sporadically detected across the South ( Brazil, Columbia, and Argentina ) and Central ( Panama and Mexico ) America and the Caribbean ( Grenada ), but there is minimal BSQV surveillance due to limited public health awareness and a lack of specific or sensitive diagnostics. BSQV exposure has been reported in a wide range of host and vector species , including humans . Little information is available in the literature and herein we summarize the published historical findings on BSQV and suggest a pathway for future studies to better understand its potential emergence into human populations. Source: Viruses,  https://www.mdpi.com/1999-4915/17/2/183 _____