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#UK - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

A small commercial flock of 69 chickens, 23 ducks and 5 geese. Increased mortality reported in chickens as well as a drop in egg production in the ducks. Samples were taken and tested positive for HPAI H5N1. Location:  Kirklees, West Yorkshire, England. Source: WOAH,  https://wahis.woah.org/#/in-review/6552 ____

Diverse #Genomic #Landscape of Swine #Influenza A Virus in #England (2014 - 2021)

Abstract Surveillance of influenza A viruses in pigs (SwIAV) is critical for identification of novel genetic groups that pose a risk to pig health and might have zoonotic potential . SwIAVs circulating in pigs in England between 2014 and 2021 were characterised using whole genome sequencing (WGS). Haemagglutinin (HA) and neuraminidase (NA) sequencing data from 82 of 368 influenza A positive samples (71 submissions) were determined, identifying H1N1 and H1N2 subtypes from the 1A classical swine and 1B human-seasonal lineages respectively. The 1B lineage viruses were predominant, accounting for 68.29% of sequenced viruses, with 1A lineage viruses comprising 31.71%, primarily from the 1A.3.3.2 clade (2009 H1N1 pandemic origin). This study characterised previously undefined diversity within the 1B lineage which led to the designation of new HA clades 1B.1.1.1, 1B.1.1.2 and 1B.1.1.3. Complete genome data were obtained from 64/82 viruses thereby updating the definition of genetic diversity t...

#UK, #England: Confirmed findings of #influenza of #avian origin in captive #mammals (as of March 25 '25)

Sheep, March 2025 One domestic sheep (Ovis aries) tested positive for influenza of avian origin (H5N1) in March 2025 . The case was identified following routine surveillance of farmed livestock on a premises in Yorkshire where highly pathogenic avian influenza (H5N1) had been confirmed in other captive birds . The single animal was a ewe with signs of mastitis but no other clinical signs . The milk was positive by polymerase chain reaction (PCR) and the blood tested positive for H5 antibodies.   All affected birds and the infected ewe were humanely culled to mitigate the risk of further disease spread. Further official testing of the remaining flock of sheep were all negative for the presence of avian influenza virus. Source: DEFRA,  https://www.gov.uk/government/publications/bird-flu-avian-influenza-findings-in-captive-mammals/confirmed-findings-of-influenza-of-avian-origin-in-captive-mammals ____

#UK, #England: #Lassa #fever contact #tracing underway

The UK Health Security Agency has been informed under the International Health Regulations that an individual travelled to England from Nigeria while they were unwell with Lassa fever at the end of February. The individual returned to Nigeria where they were diagnosed . We are now working to identify people who were in contact with the affected individual while they were in the country. Lassa fever does not spread easily between people and the overall risk to the public is very low . If you have not been contacted by UKHSA then you are very unlikely to have had any exposure to Lassa fever and do not need to take action. Lassa fever causes acute infections which can range from very mild symptoms through to a severe viral haemorrhagic fever. People usually become infected with Lassa virus through exposure to food or household items contaminated with urine or faeces of infected rats – present in some West African countries where the disease is endemic. The virus can also be spread between...

#UK, Latest #update on cases of Clade Ib #mpox

 {February 13 2025} Latest update A new case of clade Ib mpox has been detected in England, the UK Health Security Agency (UKHSA) can confirm .  The case was detected in London and the individual is now under specialist care at the Royal Free Hospital High Consequence Infectious Diseases unit. They had recently returned from Uganda , where there is currently community transmission of clade Ib mpox. The UKHSA and NHS will not be disclosing any further details about the individual. The risk to the UK population remains low . In the context of the outbreak in parts of Africa, we expect to see the occasional imported case of clade Ib mpox in the UK. This is the eighth case of clade Ib mpox confirmed in England since October 2024. This case has no links to the previous cases identified in England. Close contacts of the case are being followed up by UKHSA and partner organisations. Contacts will be offered testing and vaccination where needed to prevent further infections and they w...

#UK - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification {Cornwall}

480 mixed free-range commercial broiler and layer unit. HPAI clinical signs reported, including depression and reduced food and water intake. Samples taken were positive for H5N1. Region: England, Cornwall. Source: WOAH,  https://wahis.woah.org/#/in-review/6255 _____

#UK, #Human case of avian #influenza #H5N1 detected in #England

UKHSA has confirmed a case of influenza A(H5N1) in a person in the West Midlands region. Bird-to-human transmission of avian influenza is rare and has previously occurred a small number of times in the UK . The person acquired the infection on a farm , where they had close and prolonged contact with a large number of infected birds. The risk to the wider public continues to be very low. The individual is currently well and was admitted to a High Consequence Infectious Disease (HCID) unit. The birds were infected with the DI.2 genotype , one of the viruses known to be circulating in birds in the UK this season. This is different to strains circulating among mammals and birds in the US. Although there has been no demonstrated human-to-human transmission despite extensive recent surveillance of influenza A(H5N1), UKHSA has been tracing all individuals who have been in contact with the confirmed case of avian influenza. Those at highest risk of exposure have been offered antiviral treatmen...