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#Germany - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

  A laying hens farm in Nordrhein-Westfalen Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6832 ____

#UK - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

  {England, Cumberland} A chicken breeders flock of 43,339 birds. Increased mortality and other clinical signs (lethargy, respiratory distress, swollen heads, tremors, watery diarrhoea and excessive oral discharge) were reported. Samples taken and were tested positive for HPAI H5N1. Source: WOAH,  https://wahis.woah.org/#/in-review/6824 ____

#Italy - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Follow up report 23 [FINAL]

  The highly pathogenic avian influenza virus (HPAI), subtype H5N1 - has been detected in a commercial farm of laying hens located in the Municipality of Roverbella, Mantova Province, Lombardia region. The highly pathogenic avian influenza virus (HPAI), subtype H5N1 - has been detected in a commercial farm of laying hens located in the Municipality of Cerasara, Mantova Province, Lombardia region. The highly pathogenic avian influenza virus (HPAI), subtype H5N1 - has been detected in a commercial farm of broiler located in the Municipality of Chivasso, Torino Province, Piemonte region. The highly pathogenic avian influenza virus (HPAI), subtype H5N1 - has been detected in a commercial farm of laying hens located in the Municipality of Vigasio, Verona Province, Veneto region. The highly pathogenic avian influenza virus (HPAI), subtype H5N1 - has been detected in a commercial farm of laying hens located in the Municipality of Sona, Verona Province, Veneto region. The highly pathogenic...

Understanding avian #influenza #mortality

  {Excerpt} Highly pathogenic avian influenza caused by H5N1 viruses emerged in East Asia in the late 1990s and spread to Europe, Africa, and the Middle East , circulating in wild and domestic birds and occasionally spilling over into mammals and humans . These viruses are classified into genetic lineages called clades based on differences in the gene encoding hemagglutinin , a key surface protein involved in cell entry. In 2021, one such lineage, clade 2.3.4.4b , crossed from Europe to Canada . It spread rapidly, reaching the southern tip of South America in less than 2 years and causing massive mortality in seabirds and marine mammals , including South American sea lions (Otaria flavescens) and southern elephant seals (Mirounga leonina) (1). However, human mortality has been markedly lower in the present H5N1 outbreak than in past ones. If the virus evolves the capacity to transmit from human to human, understanding this reduction will be essential for mounting an effective respo...

#Korea (Rep. of) - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

  A poultry farm in Gyeonggi-do Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6805 ___

Characterisation of a novel #chicken-derived #H3N3 avian #influenza virus detected in #China in 2023: Pathogenicity and immunogenicity

  Abstract The poultry industry faces a constant threat from the mutation and transmission of avian influenza viruses (AIVs). While waterfowl and wild birds are natural hosts of H3N3 AIV , reports of H3N3 infections in chickens are limited. However, in 2023, a decline in egg production among laying hens in the Yancheng Region of Jiangsu Province prompted a study. This research aimed to diagnose the aetiology in laying hens through molecular virological methods and characterise the biological properties of the causative pathogens. An H3N3 AIV subtype strain, A/chicken/China/YC01/2023(H3N3), was isolated from chickens exhibiting lesions. Genome sequencing and analysis revealed a novel genetic makeup : the HA gene originated from an H3N8 AIV, the NA gene from an H10N3 AIV, and the internal genes from an H9N2 AIV, all circulating in China. Chickens experimentally infected with the isolate showed signs of Harderian gland haemorrhage, nasal mucus, tracheal circumferential bleeding , and ...

The #hemagglutinin proteins of clades 1 and 2.3.4.4b #H5N1 highly pathogenic avian #influenza viruses exhibit comparable attachment patterns to avian and #mammalian #tissues

  ABSTRACT The global spread of the A/goose/Guangdong/1/96-lineage H5N1 highly pathogenic avian influenza (HPAI) viruses has been accompanied by an expanded host range and the establishment of sustained viral transmission among dairy cattle . To evaluate if the evolving H5N1 viruses have changed tissue tropism over time , we compared the binding patterns of recombinant hemagglutinin (HA) proteins derived from clade 1 (A/Vietnam/1203/04, H5VN) and circulating clade 2.3.4.4b viruses detected from wild bird (A/Eurasian Teal/Hong Kong/AFCD-HKU-23-14009-01020/2023, H5HK) and dairy cattle (A/bovine/Ohio/B24OSU-439/2024, H5OH). The HA protein of A(H1N1)pdm09 virus was included for comparison . Using bio-layer interferometry , H1 protein preferentially bound to the α2,6-linked sialoside 6′SLNLN , while H5 proteins preferentially bound to the α2,3-linked sialoside 3′SLN . H5OH showed higher binding affinity to 3′SLN than H5HK and H5VN. The attachment patterns of H1 and H5 proteins to the re...

#Genomic #surveillance and #evolution of co-circulating avian #influenza #H5N1 and #H5N8 viruses in #Egypt, 2022–2024

  ABSTRACT For over two decades, avian influenza virus (AIV) has significantly impacted the Egyptian poultry population , with multiple subtypes and genotypes contributing to significant economic and agricultural losses. As part of an ongoing national surveillance effort , this study aimed to monitor and genetically characterize AIV circulation across various poultry sectors in Egypt . Between 2022 and 2024, a total of 446,790 swab samples were collected, representing commercial farms (n = 25,057), backyard flocks (n = 403), and live bird markets “LBM” (n = 1250) to assess the prevalence and genetic diversity of circulating AIV strains. A total of 173 sampling units were found positive for high pathogenicity (HP) AIV H5 , including farms (n = 17), backyards (n = 11), and LBMs (n = 145). The HPAIV of H5N8 subtype was dominant (n = 75) over the H5N1 (n = 27) subtypes among all sectors and bird species ( chickens, ducks, turkeys ). Whole genome sequence analysis of positive H5 samples...

#Poland - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

Poultry farms in WarmiÅ„sko-Mazurskie Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6807 ____

#Germany - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Follow up report 1

Ducks for fattening (1800), geese for fattening (100) in Mecklenburg-Vorpommern Region. Laying hens (150). ducks for fattening (2800), geese for fattening (2900) in Mecklenburg-Vorpommern Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6780 ____

Avian #influenza: First #global #dialogue targets the rising #pandemic #threat

  09/09/2025 -  Foz do Iguaçu, Brazil  In an unprecedented response to the rapid global spread of high pathogenicity avian influenza (HPAI), stakeholders and experts from across the poultry sector, public health, science, and policy spheres have convened in Brazil in a landmark meeting .  This first-ever global multisectoral dialogue aims to forge coordinated defense against the escalating threat to animal and human health and agricultural livelihoods. Avian influenza, commonly known as bird flu , is a highly contagious viral disease that primarily infects birds. The virus belongs to the Type A influenza family, which is known for its ability to mutate and change rapidly. Since 2020, HPAI has expanded rapidly across continents , devastating poultry flocks , impacting biodiversity , trade and food security , and raising concerns over its potential to spark a human pandemic . The currently circulating avian influenza panzootic is now widespread, and represents one of t...

#Spain closes several #parks and #attractions due to #birdflu #outbreak (Xinhua)

{Automatic translation from Chinese, edited} [Xinhua News Agency Micro Special] Due to the outbreak of avian influenza in many places, the Andalusia Autonomous Region in southern Spain has temporarily closed a number of parks and other attractions in recent days, including two attractions included in the UNESCO World Heritage List , and the infected animals have been killed at relevant locations. According to AFP, Seville City Hall announced on social media on the 11th that the Maria Luisa Park in the city center was closed due to the discovery of dead birds . The park will clean up the dead animals and disinfect them. The city recently closed three other parks where dead birds were found, including a World Heritage site. Catalina Garcia, an environmental official for the Andalusian autonomous region, said on social media that three outbreaks of avian influenza were detected in wild birds in Doñana National Park , a World Heritage site, and the affected birds were culled. The national ...

#Norway - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Follow up report 1

  A poultry farm in Nordland Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6767 ____

#Genetic data and #meteorological conditions suggesting #windborne #transmission of #H5N1 high-pathogenicity avian #influenza between commercial #poultry outbreaks

  Abstract Understanding the transmission routes of high-pathogenicity avian influenza (HPAI) is crucial for developing effective control measures to prevent its spread . In this context, windborne transmission , the idea that the virus could travel through the air over considerable distances, is a contentious concept, and documented cases have been rare. Here, though, we provide genetic evidence supporting the feasibility of windborne transmission . During the 2023−24 HPAI season , molecular surveillance identified identical H5N1 strains among a cluster of unrelated commercial farms about 8 km apart in the Czech Republic . The episode started with the abrupt mortality of fattening ducks on one farm. This was followed by disease outbreaks at two nearby high-biosecurity chicken farms . Using genetic, epizootiological, meteorological and geographical data, we reconstructed a mosaic of events strongly suggesting wind was the most probable mechanism of infection transmission between po...

#Bolivia - #Influenza A #H5 viruses of high pathogenicity (Inf. with) (non-poultry including wild birds) (2017-) - Immediate notification

  Neurological-respiratory disease in backyard domestic birds raised in a farm with partial laboratory results of H5 avian influenza virus . Zoning was implemented for the control of the outbreak with stamping out measures for all affected and contact birds on the farm, and surveillance will be carried out in the perifocal and protection areas. A body of water representing a possible place of contact between domestic and wild birds is located on the premises. Source: WOAH,  https://wahis.woah.org/#/in-review/6755 ____

#Portugal - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

  A poultry farm in Santarém Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6759 ____

#Germany - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

  A poultry farm in Schleswig-Holstein State. Source: WOAH,  https://wahis.woah.org/#/in-review/6760 ____

#Landscape changes elevate the #risk of avian #influenza virus diversification and emergence in the East Asian–Australasian #Flyway

  Significance Highly pathogenic avian influenza virus (HPAIV) threatens wildlife, agriculture, and humans. Along the East Asian–Australasian Flyway , a major waterfowl migration corridor and HPAIV hot spot, landscape changes are altering migratory bird distributions and increasing opportunities for wild–poultry interactions . By integrating empirical data into an individual-based model, we show that landscape change between 2000 and 2015 reshaped waterfowl migration , substantially increased wild-poultry spillover , and avian influenza virus (AIV) reassortment in poultry , our proxy for potential AIV diversification and emergence of novel subtypes. Risk regions expanded across southeastern China, the Yellow River basin, and northeastern China . These findings highlight the importance of landscape changes in potentially elevating AIV diversification and emergence, and the landscape dynamics should be integrated into future studies. Abstract Highly pathogenic avian influenza viruses...

#Bulgaria - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

  Poultry farms in Plovdiv Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6746 ____

#Argentina - High pathogenicity avian #influenza #H5 viruses (#poultry) (Inf. with) - Immediate notification

The event occurred in a laying hen farm in the province of Buenos Aires . The birds involved showed mortality and clinical signs consistent with high pathogenicity avian influenza. The suspicion is officially addressed and samples were taken. The samples tested positive for HPAI H5. The event occurred in a laying hen farm. On 17/08/25 National Service of Agri-Food Health and Quality (SENASA) received a notification concerning mortality and clinical signs consistent with high pathogenicity avian influenza (HPAI) (drooping and diarrhea). The suspicion is officially addressed, with restriction of the establishment and taking of samples for diagnosis. On 19/08/2025, samples tested positive for HPAI H5. The stamping out of all the birds in the establishment will be carried out. We will update the population data in the following follow-up reports. Source: WOAH,  https://wahis.woah.org/#/in-review/6737 ____