ETIDIOH - NEW

Abstract Mpox was first identified against the backdrop of the smallpox eradication campaign. Monkeypox virus (MPXV), the causative agent of mpox, has been maintained in animal reservoirs in the forested regions of West and Central Africa as 2 distinct clades ; clade I has historically caused more severe infection in Central Africa than clade II , historically found in West Africa . However, rapid reemergence and spread of both MPXV clades through novel routes of transmission have challenged the known characteristics of mpox. We summarize mpox demographic distribution , clinical severity , and case-fatality rates attributed to genetically distinct MPXV subclades and focus on MPXV clade Ib, the more recently identified subclade. Broad worldwide assistance will be necessary to halt the spread of both MPXV clades within mpox endemic and nonendemic regions to prevent future outbreaks. Source: US Centers for Disease Control and Prevention,  https://wwwnc.cdc.gov/eid/article/31/8/24-1551...

Executive Summary   The first ever National One Health Framework to Address Zoonotic Diseases and Advance Public Health Preparedness in the United States (NOHF-Zoonoses), 2025-2029, establishes a structure to facilitate multisectoral and transdisciplinary coordination, collaboration, and communication across the federal government .  Using the One Health approach , the framework addresses zoonotic diseases and other priority One Health issues in the United States (U.S.).  The One Health approach recognizes the interdependence of the health of humans, domestic and wild animals, plants , and the wider environment (including ecosystems).  This approach mobilizes multiple diverse sectors , disciplines, and communities to work together to promote well-being and address health and ecosystem threats.  Previous multisectoral work in the U.S . identified the critical need to formalize federal One Health coordination to address zoonotic diseases and other One Health relat...

Abstract The repeated emergence of pandemic viruses underscores the linkages between land-use change and wildlife disease , and urban-adapted wildlife are of special interest due to their close proximity to humans . However, viral diversity within urban-adapted species and their zoonotic potential remain largely unexplored. We compiled a large dataset on seven priority urban-adapted mammal species and their viruses covering over 115 countries from 1574 to 2023. These urban-adapted species host 286 virus species spanning 24 orders and 38 families , 14 of which are potentially high risk for human infection. Raccoons carried the most high-risk viruses, while raccoon dogs had increased viral positivity in urban habitats compared to raccoons, wild boars , and red foxes . Many viruses in urban-adapted species were phylogenetically related to those found in humans, and we also observed evidence of possible viral spillback . These results highlight zoonotic risks associated with urban-adapted ...