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#USA, Novel #Influenza A #H5N1 Virus: One Pediatric Case in #California {FluView}

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By G.M.

 {Excerpt}

One confirmed human infection with influenza A(H5) virus was reported to CDC this week. To date, human-to-human transmission of influenza A(H5) virus has not been identified in the United States.

This case was reported by the California Department of Public Health and occurred in a child less than 18 years old with no known contact with influenza A(H5N1) virus-infected animals or humans. The investigation into the source of infection for this case is ongoing, and no human-to-human transmission has been identified.

A specimen from the individual was tested at a public health laboratory using the CDC influenza A(H5) assay before being sent to CDC for further testing. The specimen was positive for influenza A(H5) virus using diagnostic RT-PCR at CDC. Additional analysis including genetic sequencing is underway. In response to this detection, additional case investigation and contact monitoring are being conducted by public health officials in California.

There have now been 38 total confirmed human A(H5) cases and one probable human case of A(H5) case in California. This is the second reported pediatric case in California and in the United States.

Notification to WHO of this case was initiated per International Health Regulations (IHR). More information regarding IHR can be found at http://www.who.int/topics/international_health_regulations/en/.

The CSTE position statement, which includes updated case definitions for confirmed, probable, and suspected cases is available at http://www.cste.org/resource/resmgr/position_statements_files_2023/24-ID-09_Novel_Influenza_A.pdf

An up-to-date human case summary during the outbreak by state and exposure source is available at www.cdc.gov/bird-flu/situation-summary/index.html

Information about avian influenza is available at https://www.cdc.gov/flu/avianflu/index.htm.

Interim recommendations for Prevention, Monitoring, and Public Health Investigations are available at https://www.cdc.gov/bird-flu/prevention/hpai-interim-recommendations.html.

The latest case reports on avian influenza outbreaks in wild birds, commercial poultry, backyard or hobbyist flocks, and mammals in the United States are available from the USDA at https://www.aphis.usda.gov/aphis/ourfocus/animalhealth/animal-disease-information/avian/avian-influenza/2022-hpai.

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Source: US Centers for Disease Control and Prevention, https://www.cdc.gov/fluview/surveillance/2025-week-02.html

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