ETIDIOH - NEW

 {Excerpt} Exposure Source [ State -  Exposure Associated with Commercial Agriculture and Related Operations: Dairy Herds (Cattle) - Poultry Farms and Culling Operations - Other Animal Exposure† - Exposure Source Unknown‡ -  State Total ] 1) California -  33 - 0 - 0 - 1 -  34 2) Colorado -  1 - 9 - 0 - 0 -  10 3) Louisiana -  0 - 0 - 1 - 0 -  1 {+1} 4) Michigan -  2 - 0 - 0 - 0 -  2 5) Missouri -  0 - 0 - 0 - 1 -  1 6) Oregon -  0 - 1 - 0 - 0 -  1 7) Texas -  1 - 0 - 0 - 0 -  1 8) Washington -  0 - 11 - 0 - 0 -  11 -- Source Total -  37 - 21 - 1 - 2 - 61 {+1} NOTE : One additional case was previously detected in a poultry worker in Colorado in 2022. {†} Exposure was related to other animals such as backyard flocks, wild birds, or other mammals {‡...

Abstract Influenza A is a zoonotic disease that affects dogs, pigs, horses, poultry, and birds . In this report, a meta-analysis according to PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) was conducted. Studies of influenza A viruses in dogs providing prevalence or seroprevalence in any location worldwide were included. The results in this study show that the seroprevalence for the H3N8 influenza subtype was 7.96% (95% CI: 2.03–16.8, p < 0.001), for the H3N2 subtype was 7.44% (95% CI: 4.51–10.5, p < 0.001), and for the H1N1 subtype was 3.10% (95% CI: 0.890–6.01, p < 0.001). In the case of the prevalence analysis, a prevalence of 0.395% (95% CI: 0.160–2.44) for the H3N8 subtype. For the H3N2 subtype, a prevalence of 17.8% (95% CI: 6.66–32.6, p < 0.001) was found. No publication bias was observed in the studies evaluating seroprevalence in the H3N2 and H1N1 subtypes. In the H3N8 subtype, Begg’s test indicated publication bias, but Egger’s test sh...

In an update on the mutating virus - known as H5N1 – Dr. Madhur Dhingra from the Food and Agriculture Organization, FAO, said that it had “spilled over into wildlife”.  More than 500 bird species have been infected along with at least 70 mammalian species , including the endangered California condor and polar bears .  In regions that are heavily reliant on poultry as a primary source of protein, the FAO medic insisted that avian influenza “poses a serious threat to food and nutrition security”. Economic damage Dr Dhingra warned that hundreds of millions of people’s livelihoods have been affected by the virus – an economic burden on farmers that could prevent them from investing in adequate biosafety measures. Following the emergence of H5N1 influenza virus in dairy cattle , the WHO has joined calls for strengthened surveillance and biosecurity on farms, to keep animals and people safe. The UN health agency said that in 2024, 76 people have been infected with the H5 avian influ...

 {Excerpt} He had recently returned from a trip to Congo and died on Monday evening from a suspected case of hemorrhagic fever . The victim is a 55-year-old man from Trevignano , in the province of Treviso. The news was communicated by the Public Health Hygiene Service of the Azienda Ulss 2 Marca trevigiana and diagnostic tests are underway in collaboration with the Spallanzani Institute of Rome to trace the origins of the death. (...) Source: Il Fatto Quotidiano (in Italian),  https://www.ilfattoquotidiano.it/2024/12/17/treviso-55enne-morto-febbre-emorragica-rientrato-congo/7808209/ _____

Abstract Antigenic variability among influenza virus strains poses a significant challenge to developing broadly protective, long-lasting vaccines . Current annual vaccines target specific strains, requiring accurate prediction for effective neutralization. Despite sequence diversity across phylogenetic groups, the hemagglutinin (HA) head domain's structure remains highly conserved. Utilizing this conservation, we designed cross-group chimeric HAs that combine antigenic surfaces from distant strains. By structure-guided transplantation of receptor-binding site (RBS) residues, we displayed an H3 RBS on an H1 HA scaffold . These chimeric immunogens elicit cross-group polyclonal responses capable of neutralizing both base and distal strains . Additionally, the chimeras integrate heterotrimeric immunogens , enhancing modular vaccine design. This approach enables the inclusion of diverse strain segments to generate broad polyclonal responses. In the future, such modular immunogens may s...

 {Excerpt} According to the Hanoi Center for Disease Control (CDC), in close collaboration with international health authorities, it maintains enhanced epidemiological surveillance at Noi Bai airport to quickly detect any suspected cases and implement preventive measures adapted to the evolution of the global and local health situation. (...) Source: Vietnam+,  https://fr.vietnamplus.vn/surveillance-epidemiologique-renforcee-a-laeroport-de-noi-bai-pour-prevenir-une-maladie-apparue-en-rdc-post237120.vnp   ____

 {Excerpt} (Xinhua) 13:20, December 17, 2024 LOS ANGELES, Dec. 16 (Xinhua) -- The U.S. state of California has recalled raw milk produced and packaged by Valley Milk Simply Bottled , a local dairy company based in Stanislaus County, due to detection of bird flu virus . The recall order came following the detection of Influenza-A H5N1 (bird flu) virus in samples taken from a raw milk bulk tank at the Valley Milk Simply Bottled dairy farm , said the California Department of Food and Agriculture (CDFA) in a release. The order applies to all "Valley Milk Simply Bottled Raw Cow Milk" and "DESI Milk Raw Cow Milk" distributed in quart, half-gallon, and one-gallon plastic jugs with a code date marked on the container of DEC 23 2024 through DEC 30 2024. CDFA urged consumers not to consume any product remaining in their refrigerators. No illnesses have been reported in the state yet. (...) Source: People's Daily,  http://en.people.cn/n3/2024/1217/c90000-20254910.html   __...