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Showing posts from January 14, 2025

#Influenza A virus in dairy #cattle: #infection #biology and potential mammary #gland-targeted #vaccines

Abstract Influenza, a major “One Health” threat , has gained heightened attention following recent reports of highly pathogenic avian influenza in dairy cattle and cow-to-human transmission in the USA. This review explores general aspects of influenza A virus (IAV) biology, its interactions with mammalian hosts, and discusses the key considerations for developing vaccines to prevent or curtail IAV infection in the bovine mammary gland and its spread through milk. Source: npj Vaccines,  https://www.nature.com/articles/s41541-025-01063-7 _____

#USDA Confirms Highly Pathogenic Avian #H5N1 #Influenza in Backyard #Poultry Flock in #PuertoRico

WASHINGTON, January 13, 2025 – The United States Department of Agriculture’s (USDA) Animal and Plant Health Inspection Service (APHIS) has confirmed the presence of highly pathogenic avian influenza (HPAI) in a backyard poultry flock in Puerto Rico .   This is the first case of HPAI in domestic birds in Puerto Rico during this outbreak, which began in February 2022. Samples from the flock were tested and confirmed at the APHIS National Veterinary Services Laboratories in Ames, Iowa. APHIS is working closely with animal health officials in Puerto Rico on a joint incident response and will provide appropriate support as requested.  According to the U.S. Centers for Disease Control and Prevention (CDC), the public health risk associated with these avian influenza detections in birds remains low.  As a reminder, the proper handling and cooking of all poultry and eggs to an internal temperature of 165˚F is recommended as a general food safety precaution. As part of existi...

#China reported two new #human #infections with #H9N2 avian #influenza virus and one with #H10N3 virus

 {Excerpt} -- Avian influenza A(H9N2) : -- 1) Chongqing Municipality : An one-year-old girl with onset on December 13, 2024.  -- 2) Hubei  An eight-year-old girl with onset on November 27, 2024.  -- Avian influenza A(H10N3) :  -- 1) Guangxi Zhuang Autonomous Region : A 23-year-old woman with onset on December 12, 2024.  Source: Centre for Health Protection, Hong Kong PRC SAR,  https://www.chp.gov.hk/files/pdf/2025_avian_influenza_report_vol21_wk02.pdf _____