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Showing posts with the label recombinant strain

#UK: New #mpox #strain identified in #England (#UKHSA, Dec. 8 '25)

  Latest update The UK Health Security Agency (UKHSA) has identified a new recombinant mpox virus in England in an individual who had recently travelled to Asia .   -- Genomic sequencing showed that the mpox genome contained elements of clade Ib and IIb mpox .  -- This is not unexpected as both clades are circulating , but highlights the continued potential for mpox virus to evolve and the importance of continued genomic surveillance.     -- UKHSA continues to assess the significance of the strain.   Dr Katy Sinka, Head of Sexually Transmitted Infections at UKHSA, said:    '' Our genomic testing has enabled us to detect this new mpox strain . It’s normal for viruses to evolve, and further analysis will help us understand more about how mpox is changing.   '' Although mpox infection is mild for many, it can be severe . Getting vaccinated is a proven effective way to protect yourself against severe disease, so please make su...

Local and introduced #lineages drive #MERS-CoV #recombination in Egyptian #camels

  ABSTRACT Dromedary camels are the primary reservoir for Middle East respiratory syndrome coronavirus (MERS-CoV), a zoonotic coronavirus responsible for sporadic human infections . While clade B predominates in the Arabian Peninsula and is frequently linked to zoonotic outbreaks and household secondary transmission , clade C circulates primarily in African camels , with limited evidence of human infections . The extent of MERS-CoV transmission, genetic diversity, and cross-species potential in North Africa remains poorly characterized. Here, we investigate MERS-CoV incidence, seroprevalence, and genomic recombination in dromedary camels and sympatric livestock across slaughterhouses and farms in Egypt . MERS-CoV was detected in 12% of camels sampled at slaughterhouses , with no evidence of infection in cattle, buffalo, sheep, or goats . Seroprevalence was higher in slaughtered camels (79%) than camels on farms (12%). Phylogenetic analyses of MERS-CoV genomes obtained from dromedar...

Phylogeographic Characterizations of Recent (2015–2023) #Senecavirus A Isolates from #Canada

Abstract Senecavirus A (SVA) continues to cause vesicular lesions in swine in Canada and many regions worldwide. Since the vesicular lesions caused by SVA are similar to those caused by foot and mouth disease virus , swine vesicular disease virus and vesicular stomatitis virus, a foreign animal disease investigation must be initiated to rule out these diseases. SVA isolates from pigs displaying vesicular lesions in Canada from 2015 to 2023 were sequenced, and phylogeographic analysis was performed using the complete genome sequences. The results infer that SVA has spread between the United States and Canada several times. In addition, the results suggest that SVA spreads from different regions. SVA spread was inferred from Canada into Thailand, India and Mexico and inferred from the United States to Brazil, Columbia, Chile and China with ten separate introductions. Furthermore, recombination was observed in SVA genomes from Canada, the United States and China. Source: Viruses,  htt...