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  AJR Am J Roentgenol SCHMITT JE, Smerconish S Beyond the AJR: Demystifying COVID-19-Related Brain Fog With Perfusion MRI. AJR Am J Roentgenol. 2025 May 21. doi: 10.2214/AJR.25.32998. PubMed          Br J Anaesth WELLER JM, Long J, Moore M, Henderson K, et al Effects of a national team training intervention for operating theatre teams on patient and staff outcomes: a stepped-wedge cluster-randomised trial and mixed-methods study. Br J Anaesth. 2025 May 16:S0007-0912(25)00230-2. doi: 10.1016/j.bja.2025. PubMed           Abstract available Clin Infect Dis NADIG N, Bhimraj A, Cawcutt K, Chiotos K, et al 2025 Clinical Practice Guideline Update by the Infectious Diseases Society of America on the Treatment and Management of COVID-19: Vilobelimab. Clin Infect Dis. 2025 May 22:ciaf235. doi: 10.1093. PubMed           Abstract available Int J Infect Dis HUANG Q, Kang L, Wei X, ...

  Am J Med LIPPI G, Sanchis-Gomar F, Lavie CJ The recent (2018-2022) US monthly mortality for acute myocardial infarction still peaks in December and January. Am J Med. 2025 Jan 18:S0002-9343(25)00035-X. doi: 10.1016/j.amjmed.2025. PubMed           Abstract available STAHLBERG M, Fischer K, Tahhan M, Zhao A, et al Post-Acute COVID-19 Syndrome: Prevalence of Peripheral Microvascular Endothelial Dysfunction and Associations With NT-ProBNP Dynamics. Am J Med. 2025;138:1019-1028. PubMed           Abstract available ZHOU T, Sawano M, Arun AS, Caraballo C, et al Internal Tremors and Vibrations in Long COVID: A Cross-Sectional Study. Am J Med. 2025;138:1010-1018. PubMed           Abstract available SANAL-HAYES NEM, Mclaughlin M, Hayes LD, Berry ECJ, et al Examining Well-Being and Cognitive Function in People With Long COVID and ME/CFS, and Age-Matched Healthy Controls: A...

{Summary} World Organisation for Animal Health (2025) . – The State of the World’s Animal Health 2025 . Paris, 124pp. https://doi.org/10.20506/woah.3586. Licence: CC BY-SA 3.0 IGO. Foreword Animal health is inextricably linked to human  health , the stability of ecosystems and the strength of economies. In a world facing increasingly complex global challenges – emerging infectious diseases, climate change, antimicrobial resistance and food insecurity – ensuring the health of animals is crucial. This first iteration of The State of the World’s Animal Health report is a landmark publication released by the World Organisation for Animal Health (WOAH) for its 92nd General Session of the World Assembly, which reflects our commitment to evidence-based decision-making and data-driven action. Drawing  on WOAH’s comprehensive information systems and the collective expertise of its Members and expert network, this report offers a clear, objective and timely analysis of the global animal...

Abstract The Eurasian avian-like swine (EA) H1N1 virus has been widely prevalent in the Chinese swine population and has caused infections in human . However, knowledge regarding its pathogenic mechanisms remains limited. In this study, we analyzed the pathogenic determinants of two G4 genotype EA H1N1 viruses (A/Swine/Guangdong/SS12/2017 and A/Swine/Jiangxi/1110/2017) with differing pathogenicity by constructing a series of reassortant and mutant viruses . The HA-G219A mutation was found to be determinant of pathogenicity in mice. Subsequent analyses revealed that this mutation enhances viral replication in human cells , improves thermal stability , reduces HA activation pH, and alters receptor-binding properties . Furthermore, HA-G219A mutation may be an adaptive mutation that facilitates influenza virus adaptation to swine , with its prevalence increasing in the swine population. This mutation may support cross-species transmission of EA H1N1 swine influenza viruses or genetic excha...

Abstract In 2023, highly pathogenic avian influenza (HPAI) heavily affected gulls in Europe. In July, a mass mortality event was reported in the Black-legged Kittiwake (Rissa tridactyla) breeding colony at Ekkerøy in Northern Norway . The cause was confirmed to be infection with the HPAI H5N1 clade 2.3.4.4b virus , genotype EA-2022- BB. We describe the outbreak in Kittiwakes, including pathological and virological investigations , and discuss the management and zoonotic potential . With more than 15,000 dead birds reported , we estimate that the outbreak caused a reduction in the Kittiwake population at Ekkerøy of at least 50%. Diseased birds exhibited neurological signs . Necropsy of ten birds revealed a peracute fatal systemic disease , with severe lesions in the brain and pancreas co-localizing with the presence of viral RNA and antigen. Vascular expression of α2,3-linked sialic acids and viral RNA/antigen may reflect hematogenous virus spread . Further studies should investigate th...