ETIDIOH - NEW

  {Excerpt} Risk statement This risk assessment is based on the current epidemiological and epizootic situation of Rift Valley fever (RVF) in Senegal and Mauritania , from 20 September through 8 October 2025. The risk assessment was conducted separately for each country . However, the findings indicate that the level of risk is the same for both countries across all levels, for both human and animal health .   During this period , Senegal reported 119 confirmed human RVF cases , including 16 deaths , resulting in a case fatality rate (CFR) of 13.4% . Cases were recorded across eight health districts in three regions of Senegal, with the majority in Saint-Louis Region with 110 cases (92%) followed by Louga (four cases) and Matam (one case).  The affected districts in Saint-Louis Region : Podor, Richard-Toll, Dagana, and Saint-Louis are located along the northern border with Mauritania along the Senegal River.   The most affected age groups were 15- 35 years ...

  Abstract Orf virus (ORFV), the prototype species of the Parapoxvirus genus within the Poxviridae family (subfamily Chordopoxvirinae), is a global pathogen infecting sheep, goats , and other ruminants , with zoonotic potential for humans . In this study, an outbreak of ORFV infection occurred in a sheep flock in Changling County, Jilin province, China , causing papules, pustules, and crusting lesions on the lips and eyelids. Typical parapoxvirus particles were observed using electron microscopy, and a wild ORFV strain was isolated, characterized, and designated as ORFV-CL24 . To clarify the epidemiological and genomic characteristics of ORFV in the region, we completed its whole-genome sequencing (GenBank accession number: PV126639). Genome analysis revealed that ORFV-CL24 shares a conserved structure with other isolates available in GenBank, which possess a complete genomic sequence of 138,500 bp of dsDNA harboring 131 putative open reading frames (ORFs) flanked by inverted termi...