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Showing posts with the label streptococcus pneumoniae

#Bacterial #Colonization and Life-Threatening #RSV #Infection in #children

  Highlights •  Respiratory tract bacterial colonization was highly prevalent among RSV-infected children. •  Moraxella catarrhalis colonization was significantly associated with mild RSV disease. •  Haemophilus influenzae carriage showed a trend toward increased severity. •  Household crowding independently correlated with severe RSV outcomes. •  Airway microbiota may modulate RSV clinical outcomes. Abstract Background Respiratory syncytial virus is a major cause of acute respiratory infection in children . While most cases are mild, some progress to life-threatening disease. The role of bacterial colonization in shaping respiratory syncytial virus outcomes remains incompletely understood. Objective To evaluate the association between respiratory tract bacterial colonization and respiratory syncytial virus disease severity in children. Study design Prospective cohort study conducted during 2019 and 2023. Children ≤24 months hospitalized with confirmed posi...