Preplanned Studies: #Phylogenetic and #Molecular Characteristics of An #H3N8 Avian #Influenza Virus Detected in Wild #Birds — #Beijing, #China, September 2024
Summary -- What is already known about this topic? - The H3N8 avian influenza virus (AIV) demonstrates considerable capacity for interspecies transmission and has been documented in multiple mammalian hosts , including equine and canine species. During 2022–2023, three laboratory-confirmed human infections with H3N8 were reported in China, heightening public health concerns about the zoonotic spillover potential of H3 subtype AIVs. -- What is added by this report? - This study reports the isolation of a genetically reassorted, low-pathogenicity H3N8 avian influenza virus (AIV) from an islet in Niukouyu Wetland Park, Beijing Municipality — the first detection of this viral strain in a wild environment within the city. Throat swabs collected from park staff tested negative for influenza viruses. Phylogenetic analysis demonstrated that the viral hemagglutinin gene originated from the Eurasian lineage, while the neuraminidase gene was derived from the North American lineage . Althoug...