ETIDIOH - NEW

  Overall Risk statement -- This RRA aims to assess the overall public health risk at the global level posed by the chikungunya virus (CHIKV) transmission during 2025, considering the criteria of potential risk for human health , the risk of geographical spread , and the risk of insufficient control capacities with available resources, and the implications for the 2026 transmission season .  -- Chikungunya virus (CHIKV) poses a significant and growing global health risk due to large and widespread regional outbreaks in recent years, climate-driven mosquito expansion , lack of specific treatment , and increasing international travel.  -- While mortality remains relatively low , the CHIKV infection can cause prolonged arthritis with disability as well as  severe illness in some patients.  -- From 1 January to 10 December 2025, 502 264 CHIKV disease cases including  208 335 confirmed cases, and 186 CHIKV deaths , were reported globally.  -- While certain ...

  Abstract Climate change is increasingly recognized as a major driver of emerging infectious diseases, particularly vector-borne diseases (VBDs), which are expanding in range and intensity worldwide. Europe , traditionally considered low-risk for many arboviral infections , is now experiencing autochthonous transmission of pathogens such as dengue, chikungunya, Zika virus, West Nile virus, malaria, and leishmaniasis . Rising temperatures , altered precipitation patterns , and milder winters have facilitated the establishment and spread of competent vectors , including Aedes, Anopheles, Phlebotomus, and Culex species , in previously non-endemic areas. These climatic shifts not only impact vector survival and distribution but also influence vector competence and pathogen development , ultimately increasing transmission potential. This narrative review explores the complex relationship between climate change and VBDs, with a particular focus on pediatric populations . It highlights h...

Abstract Background :  The Liao ning virus (LNV), belonging to the genus Seadornavirus within the family Sedoreoviridae , is a mosquito-borne virus . It was originally isolated from Aedes dorsalis mosquitoes in China . The original LNV strain, LNVS-NE97-31, was reported to infect several mammalian cell lines and cause hemorrhagic symptoms in mice . Subsequently, another LNV strain, LNV NSW B115745, was isolated from Australian mosquitoes ; it was reported to exhibit insect-specific infection. Materials and Methods :  Virus isolation was performed on mosquitoes collected in northern Hokkaido, Japan, in 2022 . The isolated virus was subjected to genomic and growth kinetics analyses. Results :  A LNV strain was isolated from Aedes vexans mosquitoes . Genomic sequencing and phylogenetic analysis revealed the new strain as 22WN03, and it formed a robust clade with the original Chinese strain, LNVS-NE97-31. Growth kinetics analysis did not reveal any mammalian or avian cell lin...