ETIDIOH - NEW

  Abstract Mpox is a zoonosis caused by the monkeypox virus . Here, we report Mali’s index Mpox case , which was clinically identified at the Mali–Guinea border by the national telemedicine center and confirmed by PCR . The library prepared with NextGenPCR™ MPXV Sequencing Library Prep and sequenced on Minion MK1C revealed a genome length of 197,122 bp with an average depth of 1284.4×. The strain belonged to Clade IIb G1 lineage and exhibited 85 mutations relative to NC_063383.1. To decipher genomic epidemiology, genomes ≥ 195 kb were retrieved from NCBI and aligned with MAFFT. Time-resolved phylogenetic reconstruction and ancestral trait inference were performed with TreeTime v0.11.4. A median joining network was built with Popart v1.7. Phylogeographic analysis revealed clustering with Clade IIb (G.1 lineage) linked to the May 2025 outbreak in Sierra Leone . Source:  Link:  https://www.mdpi.com/1999-4915/18/3/294 ____

  {Excerpt} Risk statement This risk assessment is based on the current epidemiological and epizootic situation of Rift Valley fever (RVF) in Senegal and Mauritania , from 20 September through 8 October 2025. The risk assessment was conducted separately for each country . However, the findings indicate that the level of risk is the same for both countries across all levels, for both human and animal health .   During this period , Senegal reported 119 confirmed human RVF cases , including 16 deaths , resulting in a case fatality rate (CFR) of 13.4% . Cases were recorded across eight health districts in three regions of Senegal, with the majority in Saint-Louis Region with 110 cases (92%) followed by Louga (four cases) and Matam (one case).  The affected districts in Saint-Louis Region : Podor, Richard-Toll, Dagana, and Saint-Louis are located along the northern border with Mauritania along the Senegal River.   The most affected age groups were 15- 35 years ...