Showing posts with label yersinia pestis. Show all posts
Showing posts with label yersinia pestis. Show all posts

Monday, October 5, 2026

Several Central Asian #countries have strengthened #border #quarantine measures after #Russia reported a possible pneumonic #plague case (NetEase, Oct. 5 '26)

 


{Excerpts}

(...)

    While Russia continues to deny a plague outbreak, neighboring countries have already taken action. 

    Following the death of a 28-year-old female employee of the Anti-Plague Research Institute in Irkutsk, Kyrgyzstan, Tajikistan, Kazakhstan, and Uzbekistan have strengthened border health and quarantine measures. 

    Russia's latest conclusion remains that the illness is "pneumonia of unknown cause," and no plague has been publicly detected in the 197 contacts identified so far.

    The deceased was named Daria Shipilova, and worked at the Irkutsk Siberian and Far Eastern Anti-Plague Research Institute, which is under the Federal Service for Supervision of Consumer Rights Protection and Human Welfare of the Russian Federation.

    She was hospitalized on September 29 with severe pneumonia and died on October 2.

    The incident quickly spiraled out of control because her workplace was not an ordinary laboratory, but an institution that specializes in researching highly dangerous infectious diseases such as plague.

    Russian local media later published an extremely frightening version: Shipilova broke a test tube containing live plague pathogens while working in the laboratory on September 25 and subsequently fell ill.

    This claim has not yet been confirmed by the Russian health authorities.

    Following expanded testing, the Russian Federal Service for Supervision of Consumer Rights Protection and Human Welfare stated that Shipilova's official diagnosis remains "pneumonia of unknown cause," and no microorganisms related to her occupational activities were detected in her biological samples.

    The Russian side also stated that the expert committee found no evidence of any incidents involving the handling of pathogenic microorganisms at the institute.

    However, the measures taken locally were not lenient.

    Following Shipilova's death, 197 people who had been in contact with her were placed under medical observation. Russian local media initially reported that several hospitals restricted access, and research institute staff were also quarantined.

    The Sherekhov aluminum plant near Irkutsk has even reinstated the requirement for masks.

    Anna Popova, Russia's top public health official, traveled to Irkutsk to attend a special meeting on the prevention and control of "suspected particularly dangerous infectious diseases."

    The leader of the neighboring Buryat Republic, Alexei Tsydenov, initially wrote directly "the woman who died of the plague," but later changed the wording to "possibly died of the plague."

    By October 5, the Russian government had further downplayed the rumors.

    Irkutsk Governor Igor Kobzev said that expanded laboratory testing did not find any pathogens related to Shipilova's professional activities, and her cause of death is still listed as "pneumonia of unknown cause."

    Kremlin spokesman Dmitry Peskov also publicly stated that day, urging the outside world not to follow rumors about a "plague outbreak" circulating online, but to rely on information officially released by the Russian health authorities.

    But Russia's neighbors clearly did not wait for the final conclusion.

    The Kyrgyz Ministry of Health announced that health quarantine checkpoints nationwide have been upgraded. Passengers, vehicles, and goods transiting the country will be subject to stricter epidemiological monitoring.

    Tajikistan's health authorities have also confirmed that they have strengthened national border health and quarantine measures, with a focus on preventing the importation of particularly dangerous infectious diseases.

    The Kazakh Ministry of Health stated that it is monitoring the situation in Irkutsk, and no cases of plague have been confirmed on the Russian side so far. Kazakhstan has assessed the risk of imported cases as "low," but health quarantine measures have been implemented at border crossings.

    Uzbekistan raised its health and epidemic prevention department's alert level earlier, with the same aim of preventing the importation of particularly dangerous infectious diseases from abroad.

    There's a place here that's easily swayed by social media.

    The "pneumonic plague" mentioned in the English report is not "pneumonia plague"; the accurate Chinese name is "pneumonic plague".

    Plague is caused by Yersinia pestis. The most common form is bubonic plague; if the bacteria invade the lungs, it can cause pneumonic plague. The biggest difference between pneumonic plague and bubonic plague is that the former can be transmitted from person to person through respiratory droplets produced by infected individuals, which is why public health departments are particularly concerned.

    However, "the existence of suspected pneumonic plague" and "the outbreak of pneumonic plague in Russia" are two completely different things.

    As of the evening of October 5, publicly available evidence could only confirm a few things: 

    ° a female employee of the anti-plague research institute had died; 

    ° Russia had initiated preventative measures as a "suspected particularly dangerous infectious disease"; 

    ° approximately 197 contacts were under medical observation; and 

    ° at least four Central Asian countries had implemented border control measures to prevent the importation of the virus.


    What remains uncertain is precisely the most frightening question: whether she was actually infected with the plague, and whether the test tube supposedly containing plague bacteria was broken.

    There's another layer of background to this mystery.

    The vast grasslands and mountains bordering Russia, Mongolia, and northwest China naturally contain plague foci. Just this September, the Russian health authorities reported a high level of plague activity in animals in the Altai region near the Mongolian border and organized disease control personnel to conduct monitoring.

    Therefore, the fact that Central Asian countries are now strengthening border health checks does not mean that they have confirmed the outbreak of plague in Russia.

    What they are doing is something else entirely: conclusions can wait, but border epidemic prevention cannot.

    To date, Russia has not released any laboratory results proving that Shipilova was infected with plague, nor has it released any reports on the pathogen strains detected in the so-called "ruptured test tube."


Source: 


Link: https://www.163.com/dy/article/L8GQQJKP05528J01.html

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Thursday, October 1, 2026

Notes from the Field: #Fatal Pneumonic #Plague — Coconino County, #Arizona, July 2025

 


Summary

    ° What is already known about this topic?

        § Pneumonic plague is a rare and often fatal disease that can be transmitted by respiratory droplets from animals or persons infected with Yersinia pestis bacteria.

    ° What is added by this report?

        § In July 2025, Arizona reported its first pneumonic plague death since 2007, in a man with occupational exposure to ill cats. Two days after the patient’s death, preliminary diagnostic test results supported a suspected pneumonic plague diagnosis, prompting immediate identification of potentially exposed persons for postexposure prophylaxis.

    ° What are the implications for public health practice?

        § In areas with endemic plague, preliminary diagnostic test results combined with clinical suspicion for pneumonic plague can result in timely public health interventions.


Abstract

Pneumonic plague is transmitted through inhalation of respiratory droplets containing the bacterium Yersinia pestis and has a nearly 100% case-fatality rate when untreated. Although Y. pestis is endemic among rodents in northern Arizona, only eight human plague cases were reported in Arizona during 2000–2024. In July 2025, Arizona reported its first pneumonic plague death since 2007.


Source: 


Link: http://dx.doi.org/10.15585/mmwr.mm7538a2

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Tuesday, September 29, 2026

#WHO reports latest global #trends in #cholera, #meningitis and #plague (WHO, Sept. 29 '26)



29 September 2026 | News release 


    Cholera deaths increased by 30% in 2025, despite fewer cases being reported to the World Health Organization (WHO).  

    In 2025, 47 countries reported 451 499 cholera cases and 7870 deaths to WHO. This is the highest number of annual cholera deaths reported to WHO since 1999. These figures reflect surveillance data reported to WHO and not the actual global burden of cholera, which is estimated to be substantially higher as many cases go unreported.  

    Seven countries – Angola, Bangladesh, the Democratic Republic of the Congo, Nigeria, South Sudan, Sudan and Yemen – accounted for around 90% of all reported cholera cases and deaths globally. The WHO African Region reported the largest burden, with a 34% increase in cases and a 58% increase in deaths compared with 2024. 

    These findings are published in the latest edition of the Weekly Epidemiological Record alongside updates about two other epidemic-prone bacterial diseases: meningitis and plague.  

    "The rise in cholera deaths is a reminder of the challenge ahead,” said Dr Chikwe Ihekweazu, Executive Director of WHO's Health Emergencies Programme. 

    “No one should be dying from cholera today when we have the tools to prevent and treat this disease. The concentration of cases and deaths in a small number of countries shows where targeted investments in safe water, sanitation and hygiene could have the greatest impact. Combined with stronger disease surveillance, community engagement, vaccination and access to quality care, these investments can help turn this trend around." 

    Cholera is an acute diarrhoeal disease caused by Vibrio cholerae bacteria. The disease spreads through food and water contaminated with faeces, especially in areas without safe water and sanitation. 

    While cholera is preventable and treatable, it can be fatal if severe dehydration is not rapidly treated. More than one in five reported cholera deaths occurred outside health facilities, highlighting that too many patients are still not reaching care in time. Among patients treated in health facilities, the fatality rate was below 1% – a threshold for adequate care – globally. However, the rate exceeded 1% in 12 countries in 2025. 

    Global production of oral cholera vaccines more than doubled between 2022 and 2025, increasing from around 30 million to approximately 80 million doses annually, significantly improving vaccine availability. Last year, the International Coordinating Group (ICG) on Vaccine Provision approved 71 million doses for use in affected countries, including 20 million doses for preventive vaccination, which resumed earlier this year after being suspended for more than three years. 


Vaccination is advancing the fight to defeat meningitis by 2030  

    Bacterial meningitis continues to place a substantial burden on countries in the African meningitis belt, an area extending from Senegal to Ethiopia where epidemics occur regularly. In 2025, 24 of the 26 countries in the region reported 21 526 suspected cases and 971 deaths to WHO, corresponding to a fatality rate of 4.5%. Among countries reporting data for both years, cases declined by 5.9% compared with the previous year.  

    Meningitis is the inflammation of the tissues surrounding the brain and spinal cord, with bacterial meningitis being the most serious type. Four types of bacteria account for most cases of bacterial meningitis worldwide. 

    Vaccination has transformed the efforts to combat meningococcal meningitis, one of the main causes of bacterial meningitis. Since the introduction of the meningococcal A conjugate vaccine in 2010, cases of serogroup A have declined by more than 99% among vaccinated populations, and no confirmed case has been reported since 2017 in countries that introduced the vaccine. 

    A vaccine offering broader protection against five meningococcal serogroups, Men5CV/MMCV, is now being introduced in the region for both outbreak response through the ICG and preventive vaccination campaigns. In 2025, Niger became the first country to carry out a country-wide campaign using this vaccine.  


Surveillance remains essential to control plague 

    Plague is a bacterial disease that usually spreads between animals through fleas and can sometimes infect people. 

    Between 2019 and 2025, 10 countries reported suspected human plague cases to WHO, six of which reported confirmed cases. Overall, 3847 suspected cases and 423 deaths were reported to WHO, corresponding to a case fatality rate of 11%. Most cases were reported from the Democratic Republic of the Congo and Madagascar, where plague remains endemic in some areas. Plague may also occur in countries that do not report cases, and annual case numbers fluctuated depending on the timing, location and magnitude of outbreaks. 

    Continued surveillance of rodent and other animal populations, together with rapid response to outbreaks, remains essential to detect plague early, reduce transmission and prevent larger outbreaks.  


About WHO 

    Dedicated to the well-being of all people and guided by science, WHO leads and champions global efforts to give everyone, everywhere, an equal chance at a safe and healthy life. We are the United Nations’ agency for health that connects nations, partners and people in more than 150 locations – leading the world’s response to health emergencies, preventing disease, addressing the root causes of health issues and expanding access to medicines and health care. Our mission is to support all countries to promote, provide and protect health. “Together for health. Stand with science”, the theme of World Health Day 2026, marks a year-long campaign to highlight science as the foundation for protecting health and well-being worldwide.


Source: 


Link: https://www.who.int/news/item/29-09-2026-who-reports-latest-global-trends-in-cholera--meningitis-and-plague

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Monday, November 17, 2025

First #assessment of #plague in terrestrial small #mammals and #fleas from Makira Natural Park and surroundings, North-eastern #Madagascar

 


Abstract

Background

Plague, a zoonosis caused by Yersinia pestis, is endemic in Madagascar but knowledge on the epidemiological situation in the northern focus remains unclear. The aim of this study was to investigate the circulation of Y. pestis in terrestrial small mammals in north eastern Madagascar, where suspected plague outbreaks have been reported.

Methods

Sampling of terrestrial small mammals and their fleas was carried out in 22 trapping sites within 9 localities of the two sectors (1 and 3) of Makira Natural Park (MNP) and surroundings, from 2020 to 2022. Yersinia pestis was investigated in terrestrial small mammal spleen samples and their fleas using bacteriological, serological and molecular methods.

Results

A total of 614 terrestrial small mammals composed of eight species and 1,754 individual fleas were collected following 4,880 trap-nights. The black rat (Rattus rattus) represented the majority (87.8%) of the small mammal species caught. Flea infestation rate was higher in sector 3 compared to sector 1. In sector 3, Xenopsylla brasiliensis, a plague vector, represented 66.4% of fleas identified. Further, one plague seropositive R. rattus individual, captured inside a house, and one Ctenocephalides felis specimen, collected on another R. rattus, was positive on PCR in this sector.

Discussion

Despite low detection rates, we confirmed the circulation of Y. pestis in our study area (one rat seropositive and one flea PCR positive) and highlight the risk of potential human transmission. Our results also suggest that R. rattus contributes to the maintenance and transmission of plague in MNP, as described for other areas in Madagascar. Further, these findings contribute to documentation of the known geographic distribution of the endemic plague vector S. fonquerniei and X. brasiliensis.

Conclusion

The confirmation of the circulation of the Y. pestis through serological and molecular diagnostics in small mammals and fleas underscores the urgent need to assess awareness levels of risk factors and symptoms to monitor among local communities and health workers and ensure that trained rapid response teams are prepared to intervene promptly upon suspect case detection. The risk and epidemiology of plague circulation in remote rural areas of Madagascar remains insufficiently studied. Addressing this gap is crucial, as a more comprehensive understanding of the distribution and dynamics of the wild animal hosts, their vectors and host-vector interactions will enhance risk assessment and prevention for plague emergence and improve mitigation and early control of potential outbreaks.

Source: PLoS Neglected Tropical Diseases, https://journals.plos.org/plosntds/article?id=10.1371/journal.pntd.0013710

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Thursday, July 17, 2025

Notes from the Field: Early-Season #Human #Plague Transmitted from an Infected #Cat — #Oregon, January 2024

 


Summary

-- What is known about this topic?

- Plague is caused by the bacterium Yersinia pestis, which is transmitted primarily through fleas from rodents. This case highlights an off-season transmission of plague. Plague is most often identified during May–August.

-- What is added by this report?

- An Oregon man sought care at an emergency department for signs and symptoms of plague on January 30, 2024, the earliest calendar date of plague recorded in the state’s history, possibly indicating a shift in the seasonality of plague incidence. The patient did not have direct contact with rodents, but did have contact with his infected cat after cutting his finger.

-- What are the implications for public health practice?

- Public health messaging and diagnostic efforts regarding plague are warranted year-round in areas with endemic disease.


Abstract

Plague is caused by the bacterium Yersinia pestis. Y. pestis is transmitted primarily through the bite of an infected rodent flea or handling of infected animals. Plague is a rare but potentially life-threatening illness in the western United States, occurring in bubonic, septicemic, or pneumonic forms, primarily affecting rural populations, and is treatable with antibiotics if diagnosed early.

Source: US Centers for Disease Control and Prevention, MMWR, https://www.cdc.gov/mmwr/volumes/74/wr/mm7426a2.htm?s_cid=mm7426a2_e&ACSTrackingID=USCDC_921-DM148456&ACSTrackingLabel=Week%20in%20MMWR%3A%20Vol.%2074%2C%20July%2017%2C%202025&deliveryName=USCDC_921-DM148456

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