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Showing posts with the label orthoebolavirus

#Thermal #tolerance and #inactivation of #Ebola virus

{Summary} HIGHLIGHTS •  The investigation demonstrated a high level of tolerance of EBOV to thermal disinfection. •  A water-bath is recommended and the tubes should be fully submerged during the process. •  The established inactivation guidelines should be followed very strictly. Dear Editor, Viruses of the genus Orthoebolavirus cause sporadic outbreaks of severe haemorrhagic fever, with case fatality rates ranging from 25% to 90% (Mahanty and Bray, 2004). Six species of the virus (Orthoebolavirus zairense, sudanense, bundibugyoense, taiense, restonense, and bombaliense) have so far been identified (Biedenkopf et al., 2023). Among these, Orthoebolavirus zairense , commonly known as Ebola virus (EBOV), stands out as the most virulent . Given its high contagiousness and lethality, EBOV must be manipulated under biosafety level 4 (BSL-4) conditions, as stipulated by the National Health Commission of the People's Republic of China's list of human pathogenic microorganisms. P...