#Cambodia notified one additional #human case of #infection with #H5N1 #influenza virus (HK CHP, Feb. 17 '26)

{Excerpt}

Avian Influenza Report - Reporting period: February 8, 2026 – February 14, 2026 (Week 7)

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- Date of report: 14/02/2026

- Country: Cambodia

- Province / Region: Kampot province

- District / City: Tuek Chhou district

- Sex: M

- Age: 30

- Condition at time of reporting: Recovered

- Subtype of virus: H5N1

(...)

Source:

Link: https://www.chp.gov.hk/files/pdf/2026_avian_influenza_report_vol22_wk07.pdf

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#Neuroinvasive #Oropouche virus in a patient with #HIV from extra-Amazonian #Brazil

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Chimeric #hemagglutinin and #M2 #mRNA #vaccine for broad #influenza subtype protection

Abstract Since multiple and unpredicted influenza viruses cause seasonal epidemics and even high-risk pandemics , developing a universal influenza vaccine is essential to provide broad protection against various influenza subtypes. Combined with the mRNA lipid nanoparticle-encapsulated (mRNA-LNP) vaccine platform and chimeric immunogen strategy , we developed a novel cocktail mRNA vaccine encoding chimeric HAs (cH5/1-BV, cH7/3) and intact M2 (termed Fluaxe), which confers broad protection against major circulating IAVs and IBVs , as well as highly pathogenic avian influenza . Two-dose intramuscular immunization of Fluaxe in mice elicited cross-reactive neutralizing antibodies , T cell responses, and long-lived immunity, resulting in robust protection against multiple lethal influenza virus infections and severe acute lung injuries . In particular, intramuscular administration stimulated systemic immunity together with a prominent lung tropism of memory cells . Moreover, Fluaxe immuniza...

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