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The ongoing outbreak of Bundibugyo virus disease, a form of Ebola virus disease caused by the Bundibugyo virus, in the Democratic Republic of the Congo is evolving rapidly. As of May 27, 2026, 1031 suspected or confirmed cases of Bundibugyo virus disease had been reported from 14 health zones across three provinces (Ituri, Nord Kivu, and Sud Kivu) in the Democratic Republic of the Congo, including 240 suspected or confirmed deaths.1 Testing has rapidly expanded for routine and retrospective assessment of suspected cases (381 confirmed cases as of June 3, 2026). Deaths are harder to retrospectively assess, with investigations ongoing (64 confirmed deaths as of June 3, 2026). Suspected cases and deaths are no longer reported in recent situation reports.2 An additional 16 cases were confirmed in Uganda, as of June 4, 2026,3 with three of those among individuals travelling from Ituri, the Democratic Republic of the Congo.4,5 Together, these observations suggest that the epidemic has been larger than ascertained; however, the true magnitude remains uncertain. Estimating the outbreak size is important to assess the scale of this public health threat and appropriately calibrate surveillance and response efforts.
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