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#Mpox, Multi-country external #situation #report no. 54 published 27 June (#WHO)



{Summary)

KEY FIGURES 

{Area - Number of reported confirmed cases - Number of deaths among confirmed cases - Number of reporting countries}

-- Global (1 Jan – 31 May 2025)* - 24 672 - 82 - 75 

Key countries (01 Jan – 22 June 2025)

- Democratic Republic of the Congo - 12 208 - 22 - ...

- Uganda - 5636 - 31  - ...

- Sierra Leone - 4294 - 28 - ...

- Burundi - 1079 - 0 - ...

{*} Most recent global surveillance data available.


Highlights

In May 2025, a total of 6823 confirmed mpox cases and 16 deaths (Case Fatality Ratio: 0.2%) were reported from 49 countries across all WHO regions.

The majority of mpox cases continue to be reported from the WHO African Region, with 18 countries currently experiencing active ongoing transmission.

Since the last report, Ethiopia and Italy have reported their first cases of mpox due to clade Ib monkeypox virus (MPXV). In addition, North Macedonia, the Republic of the Congo, and Togo have reported their first cases of mpox clade IIb MPXV. Albania has reported its first mpox case, and genomic sequencing analysis is underway to determine the clade.

Community transmission of clade Ib MPXV remains limited to countries in Central and East Africa.

In Sierra Leone, the epidemic trend is consistently declining, although recent data should be interpreted with caution due to reporting delays.

Eleven African countries have received mpox vaccines, of which seven have started mpox vaccination. More than 731 000 doses of the MVA-BN vaccine have been administered to date.

WHO has updated its guideline on clinical management and infection prevention and control for mpox.

The WHO Director-General determined that the ongoing upsurge of mpox continues to constitute a public health emergency of international concern (PHEIC), following the fourth meeting of the International Health Regulations (IHR) Emergency Committee on 5 June 2025.

(...)

Source: World Health Organization, https://www.who.int/publications/m/item/multi-country-outbreak-of-mpox--external-situation-report--54---27-june-2025

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