#Coronavirus Disease Research #References (by AMEDEO, May 10 '25)

Antiviral Res

MARTIN HJ, Hossain MA, Wellnitz J, Kelestemur E, et al
Chemical arsenal for helicase Hunters: Striking the toughest targets in antiviral research.
Antiviral Res. 2025;239:106184.
PubMed Abstract available

Int J Infect Dis

BANHOLZER N, Middelkoop K, Schmutz R, Leukes J, et al
Infection prevention and control measures during the COVID-19 pandemic and airborne tuberculosis transmission during primary care visits in South Africa.
Int J Infect Dis. 2025 May 6:107921. doi: 10.1016/j.ijid.2025.107921.
PubMed Abstract available

J Infect

RIEDMANN U, Chalupka A, Richter L, Werber D, et al
Underlying health biases in previously-infected SARS-CoV-2 vaccination recipients: a cohort study.
J Infect. 2025 Apr 30:106497. doi: 10.1016/j.jinf.2025.106497.
PubMed Abstract available

J Med Virol

MAZZOTTA V, Lepri AC, Del Borgo C, Lanini S, et al
Comparative Analysis of Early COVID-19 Treatment Efficacy in a Multicentric Regional Cohort in Italy: Emulation of a Series of Target Trials.
J Med Virol. 2025;97:e70379.
PubMed Abstract available

CENAT JM, Moshirian Farahi SMM, Dalexis RD, Muray M, et al
COVID-19 Vaccine Uptake Rates and Associated Factors in Racially Diverse Parents in Canada: The Threat From Conspiracy Beliefs and Racial Discrimination.
J Med Virol. 2025;97:e70376.
PubMed Abstract available

SANCHEZ-SIMARRO A, Panizo N, Gimenez E, Albert E, et al
Dynamics of SARS-CoV-2 Spike Receptor-Binding Domain-Targeted Specific Peripheral Memory B Cells in Patients With End-Stage Chronic Kidney Disease Undergoing Replacement Therapy Following COVID-19 Vaccination.
J Med Virol. 2025;97:e70382.
PubMed Abstract available

YANG H, Gao L, Xue Y, Zhang Z, et al
Clinical Characteristics and Treatment Efficacy in Patients With SARS-CoV-2 Positivity After Nirmatrelvir-Ritonavir Therapy.
J Med Virol. 2025;97:e70377.
PubMed Abstract available

ZHANG R, Li D, Gao P, Ruan W, et al
A SARS-CoV and SARS-CoV-2 RBD Heterodimer Vaccine Candidate.
J Med Virol. 2025;97:e70367.
PubMed Abstract available

J Virol

DAI J, Feng Y, Long H, Liao Y, et al
Dexamethasone disrupts intracellular pH homeostasis to delay coronavirus infectious bronchitis virus cell entry via sodium hydrogen exchanger 3 activation.
J Virol. 2025 May 9:e0189424. doi: 10.1128/jvi.01894.
PubMed Abstract available

LUGANO D, Mwangi K, Mware B, Kibet G, et al
Characterization of SARS-CoV-2 intrahost genetic evolution in vaccinated and non-vaccinated patients from the Kenyan population.
J Virol. 2025 May 6:e0048225. doi: 10.1128/jvi.00482.
PubMed Abstract available

JAMA

RUDMAN SPERGEL AK, Wu I, Deng W, Cardona J, et al
Immunogenicity and Safety of Influenza and COVID-19 Multicomponent Vaccine in Adults >/=50 Years: A Randomized Clinical Trial.
JAMA. 2025 May 7:e255646. doi: 10.1001/jama.2025.5646.
PubMed Abstract available

Nature

MALLAPATY S
Trump freezes 'gain of function' pathogen research - threatening all US virology, critics say.
Nature. 2025 May 7. doi: 10.1038/d41586-025-01411.
PubMed

KIYONO H, Ernst PB
Nasal vaccines for respiratory infections.
Nature. 2025;641:321-330.
PubMed Abstract available

#Neuroinvasive #Oropouche virus in a patient with #HIV from extra-Amazonian #Brazil

{Excerpt} A novel reassortant Oropouche virus (OROV) lineage (with medium [M], large [L], and small [S] RNA segments : M1L2S2) has driven Brazil's largest and most geographically widespread OROV epidemic , expanding beyond the endemic Amazon basin to establish local transmission across multiple Brazilian states and other previously unaffected Latin American countries . The rapid spread of this lineage underscores its evolutionary potential and reinforces its significance as a public health threat .1 Similar to chikungunya and Zika viruses, expanding arboviruses can exhibit unexpected clinical and epidemiological shifts , including vertical transmissions , neuroinvasive effects, and potentially fatal outcomes.2–4 Although OROV typically causes self-limited febrile illness, accumulating clinical and experimental evidence suggests neurotropic potential .5 This Correspondence describes the first confirmed case of neuroinvasive OROV infection caused by the emergent M1L2S2 lineage in ext...

Stability of #influenza viruses in the #milk of #cows and #sheep

Abstract In late 2023, H5N1 high pathogenicity avian influenza (HPAIV) started circulating in dairy cattle in the USA . High viral titres were detected in milk from infected cows , raising concerns about onwards human infections . Although pasteurisation was shown to effectively inactivate influenza viruses in milk, unpasteurised milk still poses a risk of infection, both from occupational exposure in dairies and from the consumption of raw milk. We therefore assessed how long influenza viruses could remain infectious for in milk without heat inactivation. We examined the stability of a panel of influenza viruses in milk , including a contemporary H5N1 HPAIV and a variety of other influenza A and D viruses. We incubated viruses in cows' milk under laboratory conditions : at room temperature to simulate exposure in dairies and at 4°C to simulate exposure to refrigerated raw milk. Following an isolated report of H5N1 viral RNA being detected in milk from a sheep in the UK , we also c...

#Evidence of #Viremia in Dairy #Cows Naturally Infected with #Influenza A {#H5N1} Virus, #California, #USA

Abstract We confirmed influenza A virus (IAV) by PCR in serum from 18 cows on 3 affected dairy farms in California, USA . Our findings indicate the presence of viremia and might help explain IAV transmission dynamics and shedding patterns in cows. An understanding of those dynamics could enable development of IAV mitigation strategies. Source: US Centers for Disease Control and Prevention, https://wwwnc.cdc.gov/eid/article/31/7/25-0134_article ____

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