{Summary}
Since WHO declared the ongoing outbreak of Ebola virus disease caused by Bundibugyo virus (species Orthoebolavirus bundibugyoense; BDBV) in DR Congo and Uganda a public health emergency of international concern and the Africa Centres for Disease Control and Prevention (Africa CDC) declared a public health emergency of continental security, the outbreak has continued to evolve rapidly. As of June 3, 2026, 344 laboratory-confirmed cases and 60 deaths had been reported in DR Congo, while Uganda had reported 15 confirmed cases and one death; cross-border transmission has prompted heightened preparedness and response measures across the region.1–3 The outbreak poses a substantial public health threat because diagnosis is often delayed by limited access to suitable point-of-care assays, and no licensed vaccine or approved virus-specific therapeutic currently exists for BDBV. Barriers to controlling the BDBV outbreak and priority response actions are summarised in the table.

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