Highly pathogenic avian #H5N1 #influenza A virus #replication in ex vivo #cultures of #bovine mammary #gland and teat tissues
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Our data indicate that bovine H5N1 viruses can replicate efficiently in the epithelium of the bovine teat cistern, suggesting that they invade the mammary gland through the teat canal, which is more easily accessed by viruses. H5N1 virus is thought to be transmitted among lactating dairy cattle through contaminated milking equipment and/or milker's hands during milking[23]. Proper milking procedures are required to prevent spread of HPAI H5N1 viruses in dairy cattle, thereby minimizing the risk of transmission from cows to other mammals including humans.
Source: Emerging Microbes and Infections, https://www.tandfonline.com/doi/full/10.1080/22221751.2025.2450029#d1e346
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