Skip to main content

First #H5N1 #Birdflu #Death Reported in #USA



January 6, 2025 -- CDC is saddened by Louisiana's report that a person previously hospitalized with severe avian influenza A(H5N1) illness ("H5N1 bird flu") has passed away

While tragic, a death from H5N1 bird flu in the United States is not unexpected because of the known potential for infection with these viruses to cause severe illness and death. 

As of January 6, 2025, there have been 66 confirmed human cases of H5N1 bird flu in the United States since 2024 and 67 since 2022. 

This is the first person in the United States who has died as a result of an H5 infection. 

Outside the United States, more than 950 cases of H5N1 bird flu have been reported to the World Health Organization; about half of those have resulted in death.

CDC has carefully studied the available information about the person who died in Louisiana and continues to assess that the risk to the general public remains low

Most importantly, no person-to-person transmission spread has been identified. 

As with the case in Louisiana, most H5 bird flu infections are related to animal-to-human exposures. 

Additionally, there are no concerning virologic changes actively spreading in wild birds, poultry, or cows that would raise the risk to human health. (CDC reported previously on its analysis of the viruses isolated from the patient in Louisiana.) 

However, people with job-related or recreational exposures to infected birds or other animals are at greater risk of infection. For these and others, CDC has developed prevention resources about how to protect yourself.

CDC is continually:

-- Supporting critical epidemiologic investigations with state and local partners to assess the public health impact of each H5 case.

-- Working closely with state and local partners to conduct active surveillance for H5 cases.

-- Monitoring for changes that might suggest H5 viruses are becoming better adapted to mammals and therefore might spread more easily from animals-to-humans or human-to-human or cause more severe disease.

-- Monitoring for any viral changes that could make these viruses less responsive to flu antiviral medications or the available candidate vaccine viruses.

-- Additional information about H5 bird flu is available on the CDC website.

Source: US Centers for Disease Control and Prevention, https://www.cdc.gov/media/releases/2025/m0106-h5-birdflu-death.html

_____

Comments

Popular posts from this blog

#USA, Two more #human cases of #H5N1 #birdflu reported in #California

Two cases of bird flu have been reported in San Joaquin County, California, local health officials said. According to a press release issued Friday and reported by the Sacramento Bee , health officials with San Joaquin County Public Health Services said both cases were farm workers who were exposed to infected animals . Both people are showing mild symptoms and are recovering, officials said, adding that there are 34 total confirmed cases across California. In a warning posted on Facebook, health officials said bird flu was “spreading in several farms such as poultry and cattle” and urged residents to take precautions to prevent the spread of the disease. Precautions include the use of protective equipment when handling poultry, dairy cattle or other animals that may be infected, and when handling raw and unpasteurized milk. (...) There are currently 60 confirmed cases of bird flu in the country . While most of the cases are in California , other states with confirmed cases include Col...

Viral #sepsis: #diagnosis, clinical #features, #pathogenesis, and #clinical considerations

Abstract Sepsis , characterized as life-threatening organ dysfunction resulting from dysregulated host responses to infection , remains a significant challenge in clinical practice . Despite advancements in understanding host-bacterial interactions , molecular responses, and therapeutic approaches, the mortality rate associated with sepsis has consistently ranged between 10 and 16%. This elevated mortality highlights critical gaps in our comprehension of sepsis etiology. Traditionally linked to bacterial and fungal pathogens, recent outbreaks of acute viral infections , including Middle East respiratory syndrome coronavirus ( MERS-CoV ), influenza virus, and severe acute respiratory syndrome coronavirus 2 ( SARS-CoV-2 ), among other regional epidemics, have underscored the role of viral pathogenesis in sepsis, particularly when critically ill patients exhibit classic symptoms indicative of sepsis. However, many cases of viral-induced sepsis are frequently underdiagnosed because standar...

Rapid #Surge of #Reassortant A(#H1N1) #Influenza Viruses in Danish #Swine and their #Zoonotic Potential

 Source: BioRxIV, https://www.biorxiv.org/content/10.1101/2024.12.11.627926v1?rss=1  Abstract In 2018, a single detection of a novel reassortant swine influenza A virus (swIAV) was made in Denmark . The hemagglutinin (HA) of the virus was from the H1N1 pandemic 2009 (H1N1pdm09) lineage and the neuraminidase (NA) from the H1N1 Eurasian avian-like swine lineage (H1N1av). By 2022, the novel reassortant virus (H1pdm09N1av) constituted 27 % of swIAVs identified through the Danish passive swIAV surveillance program. Sequencing detected two H1pdm09N1av genotypes ; Genotype 1 contained an internal gene cassette of H1N1pdm09 origin , Genotype 2 differed by carrying an NS gene segment of H1N1av origin . The internal gene cassette of Genotype 2 became increasingly dominant, not only in the H1pdm09N1av population, but also in other Danish enzootic swIAV subtypes . Phylogenetic analysis of the HA genes from H1pdm09N1av viruses revealed a monophyletic source , a higher substitution rat...