Skip to main content

#Influenza and Other Respiratory Viruses Research #References (by AMEDEO, April 5 '25)

 


    Ann Intern Med

  1. DACSO CC
    Coadministration of RSV + influenza or COVID-19 vaccines was noninferior to separate administration for immune responses in adults aged >/=50 y.
    Ann Intern Med. 2025 Apr 1. doi: 10.7326/ANNALS-25-00904.
    PubMed         Abstract available


    Antimicrob Agents Chemother

  2. PANG Y, Li H, Chen X, Cao Y, et al
    A phase I, single-center, randomized, open-label, three-period crossover study to evaluate the drug-drug interaction between ZSP1273 and oseltamivir in healthy Chinese subjects.
    Antimicrob Agents Chemother. 2025;69:e0172924.
    PubMed         Abstract available

  3. ZHAO L, Li C, Wang M, Zhou M, et al
    Potent antiviral activity of simnotrelvir against key epidemic SARS-CoV-2 variants with a high resistance barrier.
    Antimicrob Agents Chemother. 2025 Mar 10:e0155624. doi: 10.1128/aac.01556.
    PubMed         Abstract available


    Biochem Biophys Res Commun

  4. LIU HL, Lin S, Hung W, Chang DC, et al
    A novel replicase-mediated self-amplifying RNA amplification mechanism of the SARS-CoV-2 replication-transcription system.
    Biochem Biophys Res Commun. 2025;758:151654.
    PubMed         Abstract available


    Biochemistry

  5. E SANTO AA, Reis A, Pinheiro AA, da Costa PI, et al
    Design of Mimetic Antibodies Targeting the SARS-CoV-2 Spike Glycoprotein Based on the GB1 Domain: A Molecular Simulation and Experimental Study.
    Biochemistry. 2025;64:1541-1549.
    PubMed         Abstract available


    BMC Pediatr

  6. JAFARI N, Akbari H, Maghsoodi A, Sarbakhsh P, et al
    The attitude of the unvaccinated children's parents toward pediatric COVID-19 vaccination in Tabriz, Iran.
    BMC Pediatr. 2025;25:248.
    PubMed         Abstract available


    Epidemiol Infect

  7. MONGE S, Humphreys J, Nicolay N, Braeye T, et al
    Comparison of two methods for the estimation of COVID-19 vaccine effectiveness of the autumnal booster within the VEBIS-EHR network in 2022/23.
    Epidemiol Infect. 2025;153:e54.
    PubMed         Abstract available

  8. MIN KH, Kim JH, Gil JY, Park JH, et al
    Factors associated with carditis adverse events following SARS-COV-2-19 vaccination.
    Epidemiol Infect. 2025;153:e51.
    PubMed         Abstract available


    J Exp Med

  9. MADSEN A, Okba NMA, Pholcharee T, Matz HC, et al
    Identification of a seasonal influenza vaccine-induced broadly protective neuraminidase antibody.
    J Exp Med. 2025;222:e20241930.
    PubMed         Abstract available


    J Infect Dis

  10. FRUTOS AM, Tenforde MW, Sundaresan D, Naleway AL, et al
    Influenza-associated hospitalization rates by underlying conditions, 2016-17 to 2019-20: A retrospective cohort study.
    J Infect Dis. 2025 Mar 28:jiaf164. doi: 10.1093.
    PubMed         Abstract available


    J Virol

  11. XIAO X, Wang X, Xu F, Liang Y, et al
    Synergistic effects of PA (S184N) and PB2 (E627K) mutations on the increased pathogenicity of H3N2 canine influenza virus infections in mice and dogs.
    J Virol. 2025 Apr 4:e0198424. doi: 10.1128/jvi.01984.
    PubMed         Abstract available


    MMWR Morb Mortal Wkly Rep

  12. JOBE NB, Rose E, Winn AK, Goldstein L, et al
    Human Metapneumovirus Seasonality and Co-Circulation with Respiratory Syncytial Virus - United States, 2014-2024.
    MMWR Morb Mortal Wkly Rep. 2025;74:182-187.
    PubMed         Abstract available


    Pediatrics

  13. ROWE SL, Sullivan SG, Munoz FM, Coates MM, et al
    COVID-19 Vaccination During Pregnancy and Major Structural Birth Defects.
    Pediatrics. 2025 Mar 14:e2024069778. doi: 10.1542/peds.2024-069778.
    PubMed         Abstract available

  14. COLEY RL, Leer J, Lanteri L
    Trends in Mental and Behavioral Health Risks in Adolescents: 1999-2021.
    Pediatrics. 2025;155:e2024068774.
    PubMed         Abstract available

  15. DESILVA MB, Haapala J, Vazquez-Benitez G, Daley MF, et al
    COVID-19 and Completion of Select Routine Childhood Vaccinations.
    Pediatrics. 2025 Mar 26:e2024068244. doi: 10.1542/peds.2024-068244.
    PubMed         Abstract available


    PLoS Comput Biol

  16. VON HOENE E, Roess A, Kavak H, Anderson T, et al
    Synthetic population generation with public health characteristics for spatial agent-based models.
    PLoS Comput Biol. 2025;21:e1012439.
    PubMed         Abstract available

  17. WU L, Baker CM, Tierney N, Carville K, et al
    Quantifying the impact of contact tracing interview prioritisation strategies on disease transmission: A modelling study.
    PLoS Comput Biol. 2025;21:e1012906.
    PubMed         Abstract available


    PLoS One

  18. JOSEPH M, Li Q, Shin S
    Health diagnosis associated with COVID-19 death in the United States: A retrospective cohort study using electronic health records.
    PLoS One. 2025;20:e0319585.
    PubMed         Abstract available

  19. BAYOU FD, Getaneh FB, Asmare L, Endawkie A, et al
    Trend of home birth and its associated factors in Ethiopia during COVID-19 and social crisis (2019-2023).
    PLoS One. 2025;20:e0320859.
    PubMed         Abstract available

  20. BUGHIN J, Cincera M, Reykowska D, Zyszkiewicz M, et al
    The great divide between employees: Clustering employee "well-being" during a pandemic.
    PLoS One. 2025;20:e0294540.
    PubMed         Abstract available

  21. PARK H, Miyano S
    Computational network biology analysis revealed COVID-19 severity markers: Molecular interplay between HLA-II with CIITA.
    PLoS One. 2025;20:e0319205.
    PubMed         Abstract available

  22. YOON J, Kim S, Kwon CY, Kang JW, et al
    Kyungok-go for fatigue in patients with long COVID: Double-blind, randomized, multicenter, pilot clinical study protocol.
    PLoS One. 2025;20:e0319459.
    PubMed         Abstract available

  23. LESTARI BW, Saptiningrum E, Huria L, Fikri AR, et al
    Pre-treatment direct costs for people with tuberculosis during the COVID-19 pandemic in different healthcare settings in Bandung, Indonesia.
    PLoS One. 2025;20:e0320401.
    PubMed         Abstract available

  24. YAGIHASHI M, Sakuma A, Murakami M
    Psychotherapies and psychological support for individuals facing psychological distress during the COVID-19 pandemic: A scoping review.
    PLoS One. 2025;20:e0318192.
    PubMed         Abstract available

  25. CARMOLA LR, Roebling AD, Khosravi D, Langsjoen RM, et al
    Viral and host factors associated with SARS-CoV-2 disease severity in Georgia, USA.
    PLoS One. 2025;20:e0317972.
    PubMed         Abstract available

  26. LIU Y, She R, Xing J
    Analysis of University Students' Mental Health from the Perspective of Occupational Harmony.
    PLoS One. 2025;20:e0309490.
    PubMed         Abstract available

  27. GKEKAS A, Ronaldson SJ, Parker A, Torgerson DJ, et al
    Improving patient recruitment to randomised trials can be cost-effective: A case-study of dexamethasone from the RECOVERY trial.
    PLoS One. 2025;20:e0314593.
    PubMed         Abstract available

  28. SURACE A, Munroe C, Martinez P
    "My drinking was way worse during the pandemic": A qualitative analysis of contextual and individual factors impacting alcohol use during the COVID-19 pandemic.
    PLoS One. 2025;20:e0319977.
    PubMed         Abstract available

  29. AIZAWA T
    Socio-economic gradients in hypertension and diabetes management amid the COVID-19 pandemic in India.
    PLoS One. 2025;20:e0315867.
    PubMed         Abstract available

  30. TAO Z, Ramasamy SS, Naktnasukanjn N, Ying F, et al
    Assessing competitiveness and complementarity in agricultural trade between China and Cambodia pre-pandemic and post-pandemic.
    PLoS One. 2025;20:e0321081.
    PubMed         Abstract available

  31. TREPTOW M, Bartels C, Ruhleder M, Kratzenberg A, et al
    Divergent psychological stress response patterns to the COVID-19 pandemic in psychiatric patients with vs. without PTSD: A real-world exploratory study.
    PLoS One. 2025;20:e0318839.
    PubMed         Abstract available

  32. STUKAS S, Goshua G, Conway EM, Lee AYY, et al
    ABO blood group and COVID-19 severity: Associations with endothelial and adipocyte activation in critically ill patients.
    PLoS One. 2025;20:e0320251.
    PubMed         Abstract available

  33. AWASTHI S, Dehkharghani MZ, Fudolig M
    Emergence to dominance: Estimating time to dominance of SARS-CoV-2 variants using nonlinear statistical models.
    PLoS One. 2025;20:e0311459.
    PubMed         Abstract available

  34. MITCHELL E, Are EB, Colijn C, Earn DJD, et al
    Using artificial intelligence tools to automate data extraction for living evidence syntheses.
    PLoS One. 2025;20:e0320151.
    PubMed         Abstract available


    Proc Natl Acad Sci U S A

  35. GUAY B, Marghetis T, Wong C, Landy D, et al
    Quirks of cognition explain why we dramatically overestimate the size of minority groups.
    Proc Natl Acad Sci U S A. 2025;122:e2413064122.
    PubMed         Abstract available


    Vaccine

  36. OTORBAEVA D, Akmatova R, Cooley KM, Iwamoto C, et al
    Post-introduction evaluation (PIE) of the seasonal influenza vaccination program in Kyrgyzstan in 2023.
    Vaccine. 2025;55:127052.
    PubMed         Abstract available


    Virology

  37. ISHIGAKI H, Itoh Y
    Translational research on pandemic virus infection using nonhuman primate models.
    Virology. 2025;606:110511.
    PubMed         Abstract available

  38. BANGA NDZOUBOUKOU JL, Kamara AA, Ullah N, Lei Q, et al
    A meta-analysis on the immunogenicity of prototype, monovalent-adapted and bivalent vaccines against SARS-CoV-2 wildtype, Omicron BA.1 and Omicron BA.4/5 in healthy adults.
    Virology. 2025;606:110509.
    PubMed         Abstract available

  39. DAS SARMA J
    Murine beta-coronavirus spike protein: A major determinant of neuropathogenic properties.
    Virology. 2025;606:110499.
    PubMed         Abstract available

  40. LUNDRIGAN E, Uguccioni S, Hum C, Ahmed N, et al
    SARS-CoV-2 Nsp13 helicase modulates miR-146a-mediated signaling pathways.
    Virology. 2025;606:110493.
    PubMed         Abstract available

Comments

Popular posts from this blog

#Neuroinvasive #Oropouche virus in a patient with #HIV from extra-Amazonian #Brazil

{Excerpt} A novel reassortant Oropouche virus (OROV) lineage (with medium [M], large [L], and small [S] RNA segments : M1L2S2) has driven Brazil's largest and most geographically widespread OROV epidemic , expanding beyond the endemic Amazon basin to establish local transmission across multiple Brazilian states and other previously unaffected Latin American countries . The rapid spread of this lineage underscores its evolutionary potential and reinforces its significance as a public health threat .1 Similar to chikungunya and Zika viruses, expanding arboviruses can exhibit unexpected clinical and epidemiological shifts , including vertical transmissions , neuroinvasive effects, and potentially fatal outcomes.2–4 Although OROV typically causes self-limited febrile illness, accumulating clinical and experimental evidence suggests neurotropic potential .5 This Correspondence describes the first confirmed case of neuroinvasive OROV infection caused by the emergent M1L2S2 lineage in ext...

No evidence of immune #exhaustion after repeated #SARS-CoV-2 #vaccination in vulnerable and healthy populations

Abstract Frequent SARS-CoV-2 vaccination in vulnerable populations has raised concerns that this may contribute to T cell exhaustion , which could negatively affect the quality of immune protection. Herein, we examined the impact of repeated SARS-CoV-2 vaccination on T cell phenotypic and functional exhaustion in frail older adults in long-term care (n = 23), individuals on immunosuppressive drugs (n = 10), and healthy adults (n = 43), in Canada . Spike-specific CD4+ and CD8+ T cell levels did not decline in any cohort following repeated SARS-CoV-2 vaccination, nor did the expression of exhaustion markers on spike-specific or total T cells increase. T cell production of multiple cytokines (i.e. polyfunctionality) in response to the spike protein of SARS-CoV-2 did not decline in any cohort following repeated vaccination. None of the cohorts displayed elevated levels of terminally differentiated T cells following multiple SARS-CoV-2 vaccinations. Thus, repeated SARS-CoV-2 vaccination was...

Chimeric #hemagglutinin and #M2 #mRNA #vaccine for broad #influenza subtype protection

Abstract Since multiple and unpredicted influenza viruses cause seasonal epidemics and even high-risk pandemics , developing a universal influenza vaccine is essential to provide broad protection against various influenza subtypes. Combined with the mRNA lipid nanoparticle-encapsulated (mRNA-LNP) vaccine platform and chimeric immunogen strategy , we developed a novel cocktail mRNA vaccine encoding chimeric HAs (cH5/1-BV, cH7/3) and intact M2 (termed Fluaxe), which confers broad protection against major circulating IAVs and IBVs , as well as highly pathogenic avian influenza . Two-dose intramuscular immunization of Fluaxe in mice elicited cross-reactive neutralizing antibodies , T cell responses, and long-lived immunity, resulting in robust protection against multiple lethal influenza virus infections and severe acute lung injuries . In particular, intramuscular administration stimulated systemic immunity together with a prominent lung tropism of memory cells . Moreover, Fluaxe immuniza...