Skip to main content

#Mexico: The Ministry of #Health reports the #detection of the first #human case of avian #influenza A (#H5N1)

{Auto translated}

www.gob.mx/salud

The Ministry of Health reports the detection of the first human case of avian influenza A (H5N1) in Mexico

The case occurred in a three-year-old girl residing in the state of Durango. On April 1, the Institute of Epidemiological Diagnosis and Reference (InDRE) confirmed the result of influenza A (H5N1). The patient initially received treatment with oseltamivir and is currently hospitalized in a tertiary care unit in the city of Torreón, where her condition is reported to be serious

Once the case was confirmed, the following actions were immediately implemented: 

-- Notification to the World Health Organization, in accordance with the protocol established for this purpose in the International Health Regulations. 


Health

-- Health personnel from the Durango and Coahuila Health Services were trained in relation to the National Guide for the preparation, prevention and response to a zoonotic influenza outbreak or event at the animal-human interface

-- Intentional search operations were initiated for cases suspected of viral respiratory illness. 


Semarnat - Conanp

-- Biological surveys and sampling of wild and synanthropic birds were carried out in the area of ​​influence surrounding the home of the positive case of avian influenza A (H5N1), and a permanent monitoring system was established for the timely detection of other similar cases in wildlife living in the area.


Agriculture - Senasica

-- The Ministry of Agriculture and Rural Development, through the National Service of Health, Safety, and Agrifood Quality (Senasica), reported that no commercial production units have been affected by avian influenza A (H5N1) in any region of the country. However, Senasica continues its active epidemiological surveillance efforts to promptly identify any potential cases. If so, the corresponding national and international protocols will be implemented.


The Ministry of Health informs the population:

-- The WHO considers the public health risk of this virus to the general population to be low, so eating well-cooked chicken or eggs does not pose a risk to human health. Zoonotic influenza is a disease that can be transmitted from birds or other animals to humans. To date, there is no evidence of sustained human-to-human transmission. 

-- The Ministry of Health has a strategic reserve of 40,000 oseltamivir treatments. 

-- The population is recommended to

- Wash your hands frequently with soap and water or 70 percent alcohol-based solutions. 

- Wear a face mask if you have respiratory symptoms and ventilate spaces. 

- Cover your mouth and nose when coughing or sneezing. 

- Wash your hands before handling cooked foods and after handling raw foods. 

- Cook chicken and eggs properly (over 70°C) 

- Do not use the same utensils to handle raw and cooked foods. 

- Avoid touching or approaching wild animals. 

- Do not handle or pick up dead animals. 

- Do not touch sick or dead birds or poultry due to unknown causes. 

- Wear gloves, face masks, and protective clothing if you work on farms or slaughterhouses and have contact with birds or other animals, their products, and waste. 

-- Monitor for signs of illness or abnormal death in farm or backyard animals and report them immediately to the authorities. 

- The Ministry of Health recommends seeking medical attention if you experience fever, conjunctivitis (burning, itching, redness of the eyes), cough, sore throat, runny nose, difficulty breathing, headache, vomiting, diarrhea, bleeding, or altered consciousness after contact with sick or dead birds or other animals. 

Source: Ministry of Health, https://www.gob.mx/salud/prensa/secretaria-de-salud-informa-la-deteccion-del-primer-caso-humano-de-influenza-aviar-a-h5n1

____

Comments

Popular posts from this blog

#Neuroinvasive #Oropouche virus in a patient with #HIV from extra-Amazonian #Brazil

{Excerpt} A novel reassortant Oropouche virus (OROV) lineage (with medium [M], large [L], and small [S] RNA segments : M1L2S2) has driven Brazil's largest and most geographically widespread OROV epidemic , expanding beyond the endemic Amazon basin to establish local transmission across multiple Brazilian states and other previously unaffected Latin American countries . The rapid spread of this lineage underscores its evolutionary potential and reinforces its significance as a public health threat .1 Similar to chikungunya and Zika viruses, expanding arboviruses can exhibit unexpected clinical and epidemiological shifts , including vertical transmissions , neuroinvasive effects, and potentially fatal outcomes.2–4 Although OROV typically causes self-limited febrile illness, accumulating clinical and experimental evidence suggests neurotropic potential .5 This Correspondence describes the first confirmed case of neuroinvasive OROV infection caused by the emergent M1L2S2 lineage in ext...

No evidence of immune #exhaustion after repeated #SARS-CoV-2 #vaccination in vulnerable and healthy populations

Abstract Frequent SARS-CoV-2 vaccination in vulnerable populations has raised concerns that this may contribute to T cell exhaustion , which could negatively affect the quality of immune protection. Herein, we examined the impact of repeated SARS-CoV-2 vaccination on T cell phenotypic and functional exhaustion in frail older adults in long-term care (n = 23), individuals on immunosuppressive drugs (n = 10), and healthy adults (n = 43), in Canada . Spike-specific CD4+ and CD8+ T cell levels did not decline in any cohort following repeated SARS-CoV-2 vaccination, nor did the expression of exhaustion markers on spike-specific or total T cells increase. T cell production of multiple cytokines (i.e. polyfunctionality) in response to the spike protein of SARS-CoV-2 did not decline in any cohort following repeated vaccination. None of the cohorts displayed elevated levels of terminally differentiated T cells following multiple SARS-CoV-2 vaccinations. Thus, repeated SARS-CoV-2 vaccination was...

Chimeric #hemagglutinin and #M2 #mRNA #vaccine for broad #influenza subtype protection

Abstract Since multiple and unpredicted influenza viruses cause seasonal epidemics and even high-risk pandemics , developing a universal influenza vaccine is essential to provide broad protection against various influenza subtypes. Combined with the mRNA lipid nanoparticle-encapsulated (mRNA-LNP) vaccine platform and chimeric immunogen strategy , we developed a novel cocktail mRNA vaccine encoding chimeric HAs (cH5/1-BV, cH7/3) and intact M2 (termed Fluaxe), which confers broad protection against major circulating IAVs and IBVs , as well as highly pathogenic avian influenza . Two-dose intramuscular immunization of Fluaxe in mice elicited cross-reactive neutralizing antibodies , T cell responses, and long-lived immunity, resulting in robust protection against multiple lethal influenza virus infections and severe acute lung injuries . In particular, intramuscular administration stimulated systemic immunity together with a prominent lung tropism of memory cells . Moreover, Fluaxe immuniza...