#Coronavirus Disease Research #References (by AMEDEO, July 12 '25)

BMJ

HOUSE TA
Pandemic response: no one is immune to getting things wrong.
BMJ. 2025;390:r1415.
PubMed

BHATT N
Covid-19: Indian health ministry refutes links between sudden cardiac death and vaccination.
BMJ. 2025;390:r1426.
PubMed

Infect Control Hosp Epidemiol

NEARY M, Quan K, Tjoa T, Bittencourt CE, et al
Did universal masking during the COVID-19 pandemic reduce MRSA and MSSA acquisition in the NICU?
Infect Control Hosp Epidemiol. 2025 Jul 11:1-6. doi: 10.1017/ice.2025.10209.
PubMed Abstract available

Int J Infect Dis

BERG J, Linden K, Zaigham M, Domellof M, et al
The Association between Antenatal SARS-CoV-2 Exposure and Infant Neurodevelopment at Four Months of Age: A Prospective Multicenter Cohort Survey within the COPE Study.
Int J Infect Dis. 2025 Jul 3:107973. doi: 10.1016/j.ijid.2025.107973.
PubMed Abstract available

JIA Y, Zhang L, Xie Y, Hao L, et al
Incidence of acute respiratory infections and their associated pathogen distribution among residents in Shanghai, China: Preliminary results from community-based surveillance in the 2023-24 influenza season.
Int J Infect Dis. 2025 Jul 3:107974. doi: 10.1016/j.ijid.2025.107974.
PubMed Abstract available

J Med Virol

WANG H, Zhang Z, Gan M, Cui Z, et al
Dynamics of Crossed Acquired Immunity Against SARS-CoV-2 Variants: From Vaccine to Hybrid Immunity in China.
J Med Virol. 2025;97:e70487.
PubMed Abstract available

VAN SLAMBROUCK J, Vos R, Etienne I, Carlier F, et al
The Nationwide Impact of COVID-19 on Lung Donation and Transplantation in Belgium.
J Med Virol. 2025;97:e70486.
PubMed Abstract available

J Virol

XU Z, Li L, Gu Y, Li D, et al
CX1/BtSY2 and BANAL-20-52 exhibit broader receptor binding and higher affinities to multiple animal ACE2 orthologs than SARS-CoV-2 prototype.
J Virol. 2025 Jul 10:e0028325. doi: 10.1128/jvi.00283.
PubMed Abstract available

JAMA

SCHWANDT H, Currie J, von Wachter T, Kowarski J, et al
The Failure of Life Expectancy to Fully Rebound to Prepandemic Levels.
JAMA. 2025 Jul 9:e2510439. doi: 10.1001/jama.2025.10439.
PubMed

STAR J, Bandi P
Cancer Screening After the Onset of the COVID-19 Pandemic-Reply.
JAMA. 2025 Jul 7. doi: 10.1001/jama.2025.6934.
PubMed

WU G, Yin J, Huang Y
Cancer Screening After the Onset of the COVID-19 Pandemic.
JAMA. 2025 Jul 7. doi: 10.1001/jama.2025.6931.
PubMed

RUBIN R
The CDC No Longer Recommends COVID-19 Shots During Pregnancy-Now What?
JAMA. 2025 Jul 11. doi: 10.1001/jama.2025.11889.
PubMed

Lancet Infect Dis

CHALKIAS S, Dennis P, Petersen D, Radhakrishnan K, et al
Efficacy, immunogenicity, and safety of a next-generation mRNA-1283 COVID-19 vaccine compared with the mRNA-1273 vaccine (NextCOVE): results from a phase 3, randomised, observer-blind, active-controlled trial.
Lancet Infect Dis. 2025 Jul 7:S1473-3099(25)00236.
PubMed Abstract available

N Engl J Med

PRASAD V, Makary MA
An Evidence-Based Approach to Covid-19 Vaccination. Reply.
N Engl J Med. 2025 Jul 9:10.1056/NEJMc2507760#sa6. doi: 10.1056/NEJMc2507760.
PubMed

MEYEROWITZ EA
An Evidence-Based Approach to Covid-19 Vaccination.
N Engl J Med. 2025 Jul 9:10.1056/NEJMc2507760#sa5. doi: 10.1056/NEJMc2507760.
PubMed

DREKONJA D
An Evidence-Based Approach to Covid-19 Vaccination.
N Engl J Med. 2025 Jul 9:10.1056/NEJMc2507760#sa4. doi: 10.1056/NEJMc2507760.
PubMed

VOHRA-MILLER S, Marnik EA
An Evidence-Based Approach to Covid-19 Vaccination.
N Engl J Med. 2025 Jul 9:10.1056/NEJMc2507760#sa3. doi: 10.1056/NEJMc2507760.
PubMed

HAIDAR G, Hauschildt KE, Michaels MG
An Evidence-Based Approach to Covid-19 Vaccination.
N Engl J Med. 2025 Jul 9:10.1056/NEJMc2507760#sa2. doi: 10.1056/NEJMc2507760.
PubMed

PAPPAS G
An Evidence-Based Approach to Covid-19 Vaccination.
N Engl J Med. 2025 Jul 9:10.1056/NEJMc2507760#sa1. doi: 10.1056/NEJMc2507760.
PubMed

Nature

TORTORICI MA, Choi A, Gibson CA, Lee J, et al
Loss of FCoV-23 spike domain 0 enhances fusogenicity and entry kinetics.
Nature. 2025 Jul 9. doi: 10.1038/s41586-025-09155.
PubMed Abstract available

ATTIPA C, Warr AS, Epaminondas D, O'Shea M, et al
Feline infectious peritonitis epizootic caused by a recombinant coronavirus.
Nature. 2025 Jul 9. doi: 10.1038/s41586-025-09340.
PubMed Abstract available

#Neuroinvasive #Oropouche virus in a patient with #HIV from extra-Amazonian #Brazil

{Excerpt} A novel reassortant Oropouche virus (OROV) lineage (with medium [M], large [L], and small [S] RNA segments : M1L2S2) has driven Brazil's largest and most geographically widespread OROV epidemic , expanding beyond the endemic Amazon basin to establish local transmission across multiple Brazilian states and other previously unaffected Latin American countries . The rapid spread of this lineage underscores its evolutionary potential and reinforces its significance as a public health threat .1 Similar to chikungunya and Zika viruses, expanding arboviruses can exhibit unexpected clinical and epidemiological shifts , including vertical transmissions , neuroinvasive effects, and potentially fatal outcomes.2–4 Although OROV typically causes self-limited febrile illness, accumulating clinical and experimental evidence suggests neurotropic potential .5 This Correspondence describes the first confirmed case of neuroinvasive OROV infection caused by the emergent M1L2S2 lineage in ext...

No evidence of immune #exhaustion after repeated #SARS-CoV-2 #vaccination in vulnerable and healthy populations

Abstract Frequent SARS-CoV-2 vaccination in vulnerable populations has raised concerns that this may contribute to T cell exhaustion , which could negatively affect the quality of immune protection. Herein, we examined the impact of repeated SARS-CoV-2 vaccination on T cell phenotypic and functional exhaustion in frail older adults in long-term care (n = 23), individuals on immunosuppressive drugs (n = 10), and healthy adults (n = 43), in Canada . Spike-specific CD4+ and CD8+ T cell levels did not decline in any cohort following repeated SARS-CoV-2 vaccination, nor did the expression of exhaustion markers on spike-specific or total T cells increase. T cell production of multiple cytokines (i.e. polyfunctionality) in response to the spike protein of SARS-CoV-2 did not decline in any cohort following repeated vaccination. None of the cohorts displayed elevated levels of terminally differentiated T cells following multiple SARS-CoV-2 vaccinations. Thus, repeated SARS-CoV-2 vaccination was...

Chimeric #hemagglutinin and #M2 #mRNA #vaccine for broad #influenza subtype protection

Abstract Since multiple and unpredicted influenza viruses cause seasonal epidemics and even high-risk pandemics , developing a universal influenza vaccine is essential to provide broad protection against various influenza subtypes. Combined with the mRNA lipid nanoparticle-encapsulated (mRNA-LNP) vaccine platform and chimeric immunogen strategy , we developed a novel cocktail mRNA vaccine encoding chimeric HAs (cH5/1-BV, cH7/3) and intact M2 (termed Fluaxe), which confers broad protection against major circulating IAVs and IBVs , as well as highly pathogenic avian influenza . Two-dose intramuscular immunization of Fluaxe in mice elicited cross-reactive neutralizing antibodies , T cell responses, and long-lived immunity, resulting in robust protection against multiple lethal influenza virus infections and severe acute lung injuries . In particular, intramuscular administration stimulated systemic immunity together with a prominent lung tropism of memory cells . Moreover, Fluaxe immuniza...

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