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#USA, #CDC: Novel #Influenza A Virus Cases Report, as of Dec. 13 '24

 Source: US Centers for Disease Control and Prevention, LINK <||>

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Two probable cases of influenza A(H5) virus infection were reported to CDC this week by the Arizona Department of Health Services. To date, human-to-human transmission of influenza A(H5) virus has not been identified in the United States.


These cases occurred among two adult workers, ≥ 18 years of age, performing depopulation activities at a commercial poultry facility where highly pathogenic avian influenza (HPAI) A(H5N1) virus had been detected. While being monitored by local public health, these patients developed illness during the weeks ending November 23 and November 30, respectively. Both patients reported respiratory symptoms. One patient also reported conjunctivitis.

Specimens were collected from the patients and initially tested positive with high CT values at public health laboratories using the CDC influenza A(H5) assay. The specimens were negative for influenza A(H5) virus using diagnostic RT-PCR at CDC. These two probable cases are the first reported human influenza A(H5) cases reported in Arizona. 

No additional notification to WHO of these probable cases is required per International Health Regulations (IHR). More information regarding IHR can be found at http://www.who.int/topics/international_health_regulations/en/.

The CSTE position statement, which includes updated case definitions for confirmed, probable, and suspected cases is available at http://www.cste.org/resource/resmgr/position_statements_files_2023/24-ID-09_Novel_Influenza_A.pdf

An up-to-date human case summary during the 2024 outbreak by state and exposure source is available at www.cdc.gov/bird-flu/situation-summary/index.html

Information about avian influenza is available at https://www.cdc.gov/flu/avianflu/index.htm.

Interim recommendations for Prevention, Monitoring, and Public Health Investigations are available at https://www.cdc.gov/bird-flu/prevention/hpai-interim-recommendations.html.

The latest case reports on avian influenza outbreaks in wild birds, commercial poultry, backyard or hobbyist flocks, and mammals in the United States are available from the USDA at https://www.aphis.usda.gov/aphis/ourfocus/animalhealth/animal-disease-information/avian/avian-influenza/2022-hpai.

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