ETIDIOH - NEW

  Overview Starvation and malnutrition in Gaza are at the highest levels ever since the conflict began almost two years ago .  Deliberate blocking and delay of large-scale food, health , and humanitarian aid has cost many lives. Malnutrition is on a dangerous trajectory in the Gaza Strip , marked by a spike in deaths in July.  As of 5 September 2025, 361 Palestinians have died due to malnutrition , including 130 children .  As of 15 August 2025, Famine (IPC Phase 5)—with reasonable evidence—is confirmed in Gaza Governorate .  After 22 months of relentless conflict , over half a million people in the Gaza Strip are facing catastrophic conditions characterised by starvation, destitution and death.  Another 1.07 million people (54%) are in Emergency (IPC Phase 4), and 396 000 people (20%) are in Crisis (IPC Phase 3). More broadly, since 7 October 2023 , as reported by Ministry of Health (MoH), the number of casualties include 63 746 fatalities and 161 245 inju...

  Abstract We detected H5N1 high pathogenicity avian influenza in captive Greater Rhea (Rhea americana). Viral genetic analysis revealed the mammalian associated PB2-E627K mutation , indicating selection of mammalian-relevant mutations in ratites . Pathologic investigation of available tissues demonstrated severe multifocal necrotising inflammation , and a strong vasculotropism. Competing Interest Statement The authors have declared no competing interest. Source: BioRxIV,  https://www.biorxiv.org/content/10.1101/2025.09.08.674895v1 ____

  Abstract Influenza continues to cause significant mortality globally and possesses substantial pandemic potential . Assessing pandemic risk requires a clear understanding of existing population immunity . Leveraging a unique large-scale cohort of human sera , we evaluated total and neutralising antibody -mediated immunity to multiple haemagglutinin (HA) proteins, including those from subtypes with high pandemic potential. Our analysis reveals that population immunity is heterogeneous , with distinct age-dependent differences in responses to H5, H7, and H9 avian influenza subtypes. These shifts align with historical circulation patterns of seasonal H1N1 and H3N2 human viruses. Notably, H7 viruses are primarily neutralised through head domain epitopes , while H5 viruses are targeted mainly via stem epitopes , although in both instances some neutralisation occurred via receptor binding site-adjacent epitopes . Furthermore, H7 responses were dominated by non-glycan-targeted IgG2 anti...