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Showing posts from December 4, 2025

Local and introduced #lineages drive #MERS-CoV #recombination in Egyptian #camels

  ABSTRACT Dromedary camels are the primary reservoir for Middle East respiratory syndrome coronavirus (MERS-CoV), a zoonotic coronavirus responsible for sporadic human infections . While clade B predominates in the Arabian Peninsula and is frequently linked to zoonotic outbreaks and household secondary transmission , clade C circulates primarily in African camels , with limited evidence of human infections . The extent of MERS-CoV transmission, genetic diversity, and cross-species potential in North Africa remains poorly characterized. Here, we investigate MERS-CoV incidence, seroprevalence, and genomic recombination in dromedary camels and sympatric livestock across slaughterhouses and farms in Egypt . MERS-CoV was detected in 12% of camels sampled at slaughterhouses , with no evidence of infection in cattle, buffalo, sheep, or goats . Seroprevalence was higher in slaughtered camels (79%) than camels on farms (12%). Phylogenetic analyses of MERS-CoV genomes obtained from dromedar...

Quantitative #risk #assessment of #human #H5N1 #infection from consumption of fluid cow's #milk

  Abstract The spillover of H5N1 clade 2.3.4.4b into dairy cattle has raised concerns over the safety of fluid milk . While no foodborne infection has been reported in humans, this strain has infected at least 70 people and milk from infected cows is known to be infectious by ingestion in multiple other species. Investigation into the public health threat of this outbreak is warranted. This farm-to-table quantitative microbial risk assessment (QMRA) uses stochastic models to assess the risk of human infection from consumption of raw and pasteurized fluid cow's milk from the United States supply chains. These models were parameterized with literature emerging from this outbreak, then employed to estimate the H5N1 infection risk and evaluate multiple potential interventions aimed at reducing this risk. The median (5th, 95th percentiles) probabilities of infection per 240-mL serving of pasteurized, farmstore-purchased raw, or retail-purchased raw milk were 7.66E-19 (2.39E-20, 4.02E-17...

#Spain - #Influenza A #H5 viruses of high pathogenicity (Inf. with) (non-poultry including wild birds) (2017-) - Immediate notification

  {By Pierre Dalous - Own work, CC BY-SA 3.0, https://commons.wikimedia.org/w/index.php?curid=29066936 } This event will collect the detections made by sampling carried out in 2025. Report (LNR): 2025/005921 B. A vulture (Gyps fulvus) collected at Quintanas de Valdelucio. Source:  Link:  https://wahis.woah.org/#/in-review/7077 ____

#France, Two imported cases of MERS-CoV identified on national territory (Min. Santé, Dec. 4 '25)

{Automatic translation} The Ministry of Health, Families, Autonomy and Persons with Disabilities and Public Health France have been informed of two cases of MERS-CoV in France .  These two cases were confirmed following suggestive symptoms and a history of shared travel to the Arabian Peninsula .  Management measures have been implemented to limit the risk of virus transmission. Stéphanie Rist, Minister of Health, Families, Autonomy and Persons with Disabilities, confirms: “These patients are being monitored in hospital as a precautionary measure and their condition is stable . All management measures have been put in place to limit the risk of transmission of the virus to the patients' contacts and healthcare staff: contact tracing to offer them follow-up, barrier gestures, testing, isolation and procedures to follow in case of the appearance of symptoms, even mild ones.” These two cases occurred in individuals who had participated in the same trip , but no secondary transmis...

#Stability of Avian #Influenza #H5N1 Virus in #Milk from Infected #Cows and Virus-Spiked Milk

  {Excerpt} To the Editor : In March 2024, public health agencies in the United States reported highly pathogenic avian influenza (HPAI) virus of subtype A( H5N1 ) in dairy cattle , with virus detected in milk samples from symptomatic animals. Viral genetic fragments were subsequently found in pasteurized retail dairy products , which aroused concern about potential exposure through the human food supply . Heat treatment has been shown to reduce or eliminate infectious virus from both milk from infected cows and milk spiked with HPAI A(H5N1) virus. However, whether HPAI A(H5N1) virus in spiked milk from healthy cows replicates the properties of virus in milk from infected cows is unclear. We directly compared the stability of HPAI A(H5N1) virus in infected cows’ milk with that in spiked milk at 4°C (refrigeration temperature) and after heat treatment at 63°C (low-temperature, longer-duration pasteurization) or 72°C (high-temperature, shorter-duration pasteurization). (...) (...) So...

#Germany, #Birdflu in #Brandenburg: #Cats infected with avian #influenza – warning from the district (Tagesspiegel, Dec. 4 '25)

{Excerpt} Several cats in Neuruppin have been infected with avian influenza , according to the Ostprignitz-Ruppin district administration . They have been taken into the care of the Office for Consumer Protection and Agriculture, the district announced. A cat infected with the H5N1 strain of the avian influenza virus was found dead in a wooded area near the town. Several media outlets have reported on this.  (...) Source:  Link:  https://www.tagesspiegel.de/berlin/vogelgrippe-in-brandenburg-katzen-mit-geflugelpest-infiziert--warnung-vom-kreis-15014940.html ____