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Showing posts from October 21, 2025

Cross-Species #Transmission #Risks of a #Quail-Origin #H7N9 #Influenza Virus from #China Between Avian and #Mammalian Hosts

  Abstract The H7N9 influenza viruses, which are capable of causing severe respiratory syndrome in humans , were first discovered to infect humans in 2013 and continue to pose a persistent public health threat . Quail has been proposed as a potential intermediate host that may facilitate the emergence of novel reassorted influenza A viruses with the capacity to infect humans across species barriers; however, information on the biological characterization of quail H7N9 remains limited. In this study, we isolated and identified an avian H7N9 influenza virus from quails , designated as A/quail/Hebei/CH06-07/2018 (H7N9) and abbreviated as CH06-07, in Hebei, China . Phylogenetic analyses revealed that both the HA gene and the NA gene of CH06-07 were clustered in the Eurasian lineage . Furthermore, CH06-07 exhibited binding affinity for both α2,3-linked and α2,6-linked sialic acid receptors and demonstrated high pathogenicity in both quails and mice . Notably, transmission studies reveal...

#Italy, #WNV & #USUV Integrated #Surveillance - Weekly Bulletin No. 14, 15 Ocotber 2025 (ISS, edited)

  {Summary} -- New human cases of West Nile Virus infection continue to be reported albeit with reduced intensity.  -- During current epidemiological week (from  9 to 15 October 2025)  26 new confirmed cases have been reported.  -- The total number of cases so far is 767 (they were 740 last week), of these:  - 366 were West Nile Neuroinvasive Disease (WNND): 17 in Piedmont, 56 Lombardy, 34 Veneto, 4 Friuli-Venezia Giulia, 1 Liguria, 32 Emilia-Romagna, 10 Tuscany, 1 Marche, 86 Latium, 2 Molise, 83 Campania, 2 Apulia, 2 Basilicata, 5 Calabria, 3 Sicily, 28 Sardinia,  - 57 were asymptomatic cases among blood donors ,  - 333 were West Nile Fever cases (of which 1 imported from Kenya, 1 from Egypt and 1 from Maldive),  - 3 asymptomatic cases,  - eight unspecified cases.  -- Among confirmed cases, 69 fatalities  have been reported: 7 in Piedmont, 9 Lombardy, 2 Emilia-Romagna, 18 Latium, 29 Campania, 2 Calabria, 1 Sicily, 1 Sardinia....

#Cambodia notified two additional #human cases of infection with #influenza #H5N1, #Bangladesh one case of #H5, #China four cases of #H9N2 (HK CHP, Nov. 21 '25)

{Excerpt} This Week : [Date of report - Country - Province / Region District / City - Sex - Age - Condition at time of reporting  - Subtype of virus] 1) .../10/2025 - Cambodia - Takeo Province - F - 14 - Hospitalised - H5N1  2) 16/10/2025 - Cambodia - Kampong Speu Province - F - 3 - Under intensive care - H5N1 (...) [Place of occurrence - No. of cases  (No. of deaths) - Details] -- Bangladesh - 1(0)  - Avian influenza A(H5) :  1) Sylhet Division : A boy with onset on July 27, 2025.  -- Chinese Mainland - 4(0)  - Avian influenza A( H9N2 ):  - Guangdong Province :  1) An individual with onset in February 2025. The case was retrospectively reported.  - Guangxi Zhuang Autonomous Region :  2, 3) Two individuals with onset in February 2025. Both cases were retrospectively reported.   - Tianjin Municipality :  4) An individual with onset in February 2025. The case was retrospectively reported.  -- Mexico - 1(0)  - ...

Spatial #Variation of #SARS-CoV-2 #Exposure in Urban #Rodents from the Metropolitan Area of Buenos Aires, #Argentina: Implications for Public Health in Latin American Cities

  Abstract Background :  The COVID-19 pandemic , driven by the SARS-CoV-2 virus, has become an unprecedented global public health challenge . Comprehensive investigation of the virus transmission dynamics requires exploration of all potential routes , including the role of animal reservoirs . This study aimed to assess the presence of SARS-CoV-2 RNA and antibodies in urban rodents captured within two landscape units (low-income neighborhoods and green spaces) in the metropolitan area of Buenos Aires (MABA), Argentina. Methods :  Between July 2020 and September 2022, 125 synanthropic rodents (68 Rattus norvegicus, 22 R. rattus, and 35 Mus musculus) from seven low-income neighborhoods and seven green spaces in the MABA were captured and examined for SARS-CoV-2 exposure and infection by indirect immunofluorescence serology and RT-qPCR, targeting the N, E, and ORF1ab genes. Results :  Two M. musculus and six R. norvegicus from five different low-income neighborhoods test...