ETIDIOH - NEW

  {England, Suffolk} Turkey fattening unit.  Source: WOAH,  https://wahis.woah.org/#/in-review/6954 ____

  Abstract Since 2020, high pathogenicity avian influenza virus (HPAIV) infections in wild birds have been frequently reported . Because HPAIV infection has occasionally caused outbreaks in captive rare birds , application of antiviral drugs for treatment purposes against them has been considered from the perspective of conservation medicine . In this study, the therapeutic efficacy of baloxavir marboxil (BXM) was evaluated using a duck model to help establish the post-infection treatment for rare birds . Sixteen four-week-old ducks were divided into four groups and intranasally inoculated with the HPAIV strain A/crow/Hokkaido/0103B065/2022 ( H5N1 ). BXM was orally administered once daily at doses of 12.5, 2.5, 0.5, and 0 mg/kg to each of the four groups from 2 to 6 days post-infection. Blood samples were collected at 2, 8, and 24 hours after the initial BXM administration to measure the plasma concentrations of its active form, baloxavir acid (BXA). All ducks were monitored until ...

  Last updated 27 October 2025 Latest update UKHSA is aware of small numbers of locally-acquired cases of clade Ib mpox in the USA , Spain, Italy , the Netherlands and Portugal which have no connection to countries with known clade Ib mpox transmission.   This suggests there is now community transmission of clade Ib mpox globally . Most of the new cases identified in Europe and the USA have been in gay, bisexual and other men who have sex with men , a population in which clade Ib mpox transmission has not previously been observed.   Mpox is usually a mild infection , and clade Ia and Ib mpox are no longer classified as a high-consequence infectious disease (HCID). However, it can be severe in some cases.  The UK has a routine mpox vaccination programme in place for eligible groups, including those who:   -- have multiple sexual partners   -- have group sex   -- visit sex-on-premises venues   Studies show that the vacc...

A wild bird from Gruidae Spp. in Saarland Region. Source WOAH,  https://wahis.woah.org/#/in-review/6940 ____

  Abstract Avian influenza viruses (AIVs) are a global public health risk; human infection is typically associated with high mortality . While the relationship between several mammalian adaptive mutations and host factors have been described, it is unknown whether additional uncharacterised mutations lead to adaptation. Here, we combine phylogenetic analysis and complementary experimental methods to quantify the impact of novel mutations that emerge at the avian-mammal interface . We constructed phylogenetic trees of mammalian and avian influenza sequences for the polymerase (PA, PB1, PB2) and nucleoprotein (NP) segments and identified potential avian to mammal spillover events. We found >6500 mutations across the polymerase and NP, including known signatures of mammalian adaptation such as PB2 E627K and D701N which occurred independently in mammals 143 and 56 times respectively. We selected 95 mutations which were mostly undescribed and emerged independently multiple times in a...

  A protection zone (3km) and a surveillance zone (10 km) have been put in place around the infected farm and all other restrictions and necessary measures according to Regulation (EU) 2016/429 and (EU) 2020/687. {Tomelilla} Fattening turkeys. The turkeys were reported showing clinical signs of increased mortality 24 October and were euthanasia was finalized 26 October. A protection zone (3 km) and a surveillance zone (10 km) have been put in place around the infected farm and all other restrictions and necessary measures according to Regulation (EU) 2016/429 and EU DR 2020/687 are applied. Source: WOAH,  https://wahis.woah.org/#/in-review/6939 ____

  {Di Frank Liebig - Archiv Frank Liebig, CC BY-SA 3.0 de, https://commons.wikimedia.org/w/index.php?curid=56812600 } Wild birds belonging to the Gruidae Species in Berlin Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6938 ____

  {By Charles J. Sharp - Own work, from Sharp Photography, sharpphotography.co.uk, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=66151818 } A wild Great Wild Pelican in Ha Zafon Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6936 ____

Wild Mute Swans in Klaipedos, Vilniaus, Panevezio Regions. Source: WOAH,  https://wahis.woah.org/#/in-review/6923 ____

{Baden-Württemberg] Turkeys for fattening (1200), ducks for fattening (2400), geese for fattening (1200), broilers (6500), laying hens (4000). Source: WOAH,  https://wahis.woah.org/#/in-review/6927 ____

{By Andreas Trepte - Own work, CC BY-SA 2.5, https://commons.wikimedia.org/w/index.php?curid=39163967 } Wild Common Cranes. Source: WOAH,  https://wahis.woah.org/#/in-review/6918 ____

 Public Domain. Source: WikiArt,  https://www.wikiart.org/en/ancient-greek-painting/terracotta-head-of-a-man--600 ____

  Di Smiley.toerist - Opera propria, CC BY-SA 3.0,  https://commons.wikimedia.org/w/index.php?curid=7690411 Source: Wikipedia,  https://it.wikipedia.org/wiki/Automotrice_FS_RALn_60 ____

  By Henschel & Sohn Cassel - https://orka.bibliothek.uni-kassel.de/viewer/fullscreen/02008090546707/1/ , Public Domain,  https://commons.wikimedia.org/w/index.php?curid=164392169 Source: Wikipedia,  https://en.wikipedia.org/wiki/Henschel_%26_Son ____

  Br J Anaesth THOMAS C, Pearse RM Socioeconomic deprivation and health inequity: independently associated with postoperative outcomes, and does this matter? Br J Anaesth. 2025;135:1141-1143. PubMed           Abstract available Clin Infect Dis TARTOF SY, Aliabadi N, Goodwin G, Slezak J, et al Estimated Vaccine Effectiveness for Respiratory Syncytial Virus-Related Acute Respiratory Illness in Older Adults: Findings From the First Postlicensure Season. Clin Infect Dis. 2025 Oct 21:ciaf496. doi: 10.1093. PubMed           Abstract available MANABE YC, Hamill MM, Palamountain KM, Achenbach CJ, et al The Critical Importance of Clinical Use Case to Inform Point-of-Care Technology Development: A Case Study of Human Immunodeficiency Virus Nucleic Acid Assays in the United States. Clin Infect Dis. 2025 Oct 23:ciaf510. doi: 10.1093. PubMed           Abstract available Graefe...

  Antiviral Res BESSONNE M, Morel J, Nevers Q, Groutsch J, et al Inhibition of influenza virus replication by artificial proteins (alphaReps) targeting its RNA-polymerase. Antiviral Res. 2025 Oct 21:106300. doi: 10.1016/j.antiviral.2025.106300. PubMed           Abstract available BMC Pediatr WONG K, Ducharme R, Murphy MSQ, Clarke AE, et al SARS-CoV-2 infection in pregnancy and infant outcomes in the first year of life: a retrospective cohort study. BMC Pediatr. 2025;25:842. PubMed           Abstract available MAGGIO ABR, Palomo S, Joye R, Huguet H, et al Reduced aerobic capacity in children with multisystem inflammatory syndrome in children (MIS-C) after PICU admission: a retrospective cohort study, 2020-2022. BMC Pediatr. 2025;25:835. PubMed           Abstract available Cell HICKMAN HD, Moutsopoulos NM Don't forget to floss! An innovative approach for vaccine del...

  {Excerpt} Risk statement This risk assessment is based on the current epidemiological and epizootic situation of Rift Valley fever (RVF) in Senegal and Mauritania , from 20 September through 8 October 2025. The risk assessment was conducted separately for each country . However, the findings indicate that the level of risk is the same for both countries across all levels, for both human and animal health .   During this period , Senegal reported 119 confirmed human RVF cases , including 16 deaths , resulting in a case fatality rate (CFR) of 13.4% . Cases were recorded across eight health districts in three regions of Senegal, with the majority in Saint-Louis Region with 110 cases (92%) followed by Louga (four cases) and Matam (one case).  The affected districts in Saint-Louis Region : Podor, Richard-Toll, Dagana, and Saint-Louis are located along the northern border with Mauritania along the Senegal River.   The most affected age groups were 15- 35 years ...

  Summary Background Since October, 2023, Palestinian children in the Gaza Strip have suffered war-induced displacement, food insecurity, malnutrition, and elevated risks of famine and mortality . In this study, we aimed to document the extent of, and patterns in, wasting malnutrition in children aged 6–59 months across the Gaza Strip between January, 2024, and August, 2025. Methods This longitudinal, cross-sectional, surveillance study was conducted across a total of 16 UN Relief and Works Agency for Palestine Refugees in the Near East health centres and 78 medical points established within school shelters and tent encampments across the five governorates of Gaza. Children aged 6–59 months were screened for wasting malnutrition by mid-upper arm circumference (MUAC) measurement. Children with a MUAC of less than 125 mm were enrolled into therapeutic feeding regimens. MUAC Z scores were derived from published WHO age-specific and sex-specific arm circumferential growth curves. Month...

  Abstract Greece is one of the countries in Europe most affected by West Nile virus (WNV), and since 2010, when the virus caused a large outbreak with 197 human neuroinvasive cases , outbreaks occur almost every year. Mosquito surveillance is an indirect sign of virus circulation; therefore, the purpose of the study was the molecular detection of WNV in 45,988 C. pipiens s.l. mosquitoes collected during 2024 in four Regions of Greece and the genetic characterization of the virus strains. WNV was detected in 41 of 1316 ( 3.12% ) Culex spp. mosquito pools . Next-generation sequencing was applied to the WNV-positive samples that had a high viral load . All WNV sequences belong to Cluster B of the sub-lineage Europe WNV-2A presenting a temporal clustering. The WNV infection rates varied highly across the Regions, regional units and months, being higher in Thessaly and Central Macedonia Regions , especially in July and September. All mosquito pools were also tested for Usutu virus (USU...

  {England} Premises of 32,000 free range laying hens. Samples taken were positive for HPAI H5N1. Birds presented clinical signs prior to testing. Source: WOAH,  https://wahis.woah.org/#/in-review/6914 ____