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#Cats infected with #H5N1 avian #influenza – a new infectious disease in #Poland

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By G.M.

 


Abstract

Avian influenza virus (AIV) infections in cats are a new and not fully understood  problem in Poland. These infections have drawn the attention of both veterinarians  and human medical practitioners, mainly because of their zoonotic  potential, i.e. possible spreading to humans and other mammals. In wild felids as  well as in domestic cats, AIV can cause severe infections, often ending in death.  Highly pathogenic avian influenza virus (HPAIV) and low pathogenic avian influenza virus (LPAIV) have been identified, with the recent H5N1 (2.3.4.4b  clade) outbreak affecting poultry, wild birds and carnivores.  Transmission likely occurs through contact with infected birds, their excretions or  contaminated raw poultry, while cat-to-cat transmission remains unconfirmed.  First reported in Thailand in 2003, H5N1 infections in cats have since occurred in  multiple countries. In Poland, 25 confirmed cases were identified in June 2023,  with genetic sequencing linking the virus to strains detected in local wild birds.  The virus primarily replicates in the lower respiratory tract, spreading via viremia  or nerve fibers, causing multi-organ failure. While avian influenza in cats is severe  and often fatal, it should not yet be considered an epidemic. Further  interdisciplinary research is essential to clarify transmission routes and assess the  zoonotic risk. Additionally, differential diagnosis should include rabies, which presents similar neurological symptoms and remains a critical public health  concern. This article presents the current knowledge of H5N1 virus infection in  cats, especially the possible routes for its spreading, the current epizootic  situation of the disease around the world, its pathogenesis, clinical course and  methods of diagnosis.

Source: 


Link: https://journals.pan.pl/dlibra/publication/157284/edition/137625/content

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