ETIDIOH - NEW

{Nitriansky Region} Commercial poultry farm - fattenning turkeys, laying hens and pullets (in toal 36 000 heads). From 3.2. to 5.2. mortaliy in one barn up to100% (7000 fattening turkeys). Restriction zones (3 and 10 km) have been established. Epidemiological enquiry and depopulation of the farm are ongoing.  Source:  Link:  https://wahis.woah.org/#/in-review/7250 ____

  Abstract Influenza (flu) is a common respiratory virus with seasonal global spread. Zoonotic viruses can occasionally cross species, leading to pandemic-level spread , and for flu viruses, this is considered an “antigenic shift ”. The flu can be particularly severe during pregnancy due to immune system adaptations that occur during pregnancy, with prior global pandemics causing excess hospitalizations, deaths, and other complications in the mothers and the neonates. We aim to review the current literature with respect to novel avian H5N1 and the potential impact of infection with flu during pregnancy. A systematic literature search was conducted. Here we provide a rapid summary of epidemiology and understanding of viral spread , published risks of H5N1 in pregnancy, the unique physiologic, cellular, and molecular adaptations making H5N1 infection unique in pregnancy, implementation of an effective vaccine program in event of a pandemic specific to pregnant individuals, optimizing...

  Abstract A case of H5N6 avian influenza was reported in Anhui Province, China . The viral titers in the patient's lungs and pharynx decreased rapidly after oseltamivir treatment , yet it still fatal . The whole genome sequencing suggested that it derived from four distinct sources and classified within the 2.3.4.4b clade . Source:  Link:  https://www.sciencedirect.com/science/article/pii/S1684118226000034?via%3Dihub ____

  Highlights •  74% pooled MERS-CoV seroprevalence in African dromedaries •  Highest MERS-CoV RNA incidence (15.3%) observed in juvenile dromedaries •  2.4% pooled MERS-CoV seroprevalence in camel -exposed humans •  African MERS-CoV clade C exhibits unique polymorphisms •  Clade-specific features might explain low MERS-CoV infection rates in Africa Abstract Objective We explored factors contributing to the low human MERS-CoV prevalence in Africa by assessing MERS-CoV epidemiological and genomic features. Methods We followed the PRISMA guidelines. We searched for articles on epidemiological and virological MERS-CoV characteristics in humans and camels in Africa until August 2025. We used a generalised linear mixed-effects model to calculate pooled proportions. We identified relevant polymorphisms in African MERS-CoV lineages compared with the prototypic EMC/2012 and contemporary Arabian MERS-CoV (clade B5). Results We included 53 articles, with 31 used in th...

  Abstract Middle East respiratory syndrome coronavirus (MERS-CoV) was identified as a human pathogen in 2012 and causes ongoing sporadic infections and outbreak clusters . Despite case fatality rates (CFRs) of over 30% and considerable pandemic potential , a safe and efficacious vaccine has not been developed. Here we report the design, characterization, and preclinical evaluation of MERS-CoV antigens . Our lead candidate comprises a stabilized spike displayed on a self-assembling ferritin nanoparticle that can be produced from a high-expressing, stable cell pool . This vaccine elicits robust MERS-CoV pseudovirus and authentic virus neutralizing antibody titers in BALB/c mice. Immunization of male non-human primates (NHPs) with one dose of Alhydrogel-adjuvanted vaccine elicited a > 103 geometric mean titer of pseudovirus neutralizing antibodies that was boosted with a second dose. Sera from these NHPs exhibited cross-reactivity against spike-pseudotyped lentiviruses from MERS-C...

  A fattening duck holding in Bács-Kiskun Region. Source:  Link:  https://wahis.woah.org/#/in-review/7252 ____