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#Sweden - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

  A protection zone (3km) and a surveillance zone (10 km) have been put in place around the infected farm and all other restrictions and necessary measures according to Regulation (EU) 2016/429 and (EU) 2020/687. {Tomelilla} Fattening turkeys. The turkeys were reported showing clinical signs of increased mortality 24 October and were euthanasia was finalized 26 October. A protection zone (3 km) and a surveillance zone (10 km) have been put in place around the infected farm and all other restrictions and necessary measures according to Regulation (EU) 2016/429 and EU DR 2020/687 are applied. Source: WOAH,  https://wahis.woah.org/#/in-review/6939 ____

#Germany - #Influenza A #H5N1 viruses of high pathogenicity (Inf. with) (non-poultry including wild birds) (2017-) - Immediate notification

  {Di Frank Liebig - Archiv Frank Liebig, CC BY-SA 3.0 de, https://commons.wikimedia.org/w/index.php?curid=56812600 } Wild birds belonging to the Gruidae Species in Berlin Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6938 ____

#Israel - #Influenza A #H5N1 viruses of high pathogenicity (Inf. with) (non-poultry including wild birds) (2017-) - Immediate notification

  {By Charles J. Sharp - Own work, from Sharp Photography, sharpphotography.co.uk, CC BY-SA 4.0, https://commons.wikimedia.org/w/index.php?curid=66151818 } A wild Great Wild Pelican in Ha Zafon Region. Source: WOAH,  https://wahis.woah.org/#/in-review/6936 ____

#Lithuania - #Influenza A #H5N1 viruses of high pathogenicity (Inf. with) (non-poultry including wild birds) (2017-) - Immediate notification

Wild Mute Swans in Klaipedos, Vilniaus, Panevezio Regions. Source: WOAH,  https://wahis.woah.org/#/in-review/6923 ____

#Germany - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

{Baden-Württemberg] Turkeys for fattening (1200), ducks for fattening (2400), geese for fattening (1200), broilers (6500), laying hens (4000). Source: WOAH,  https://wahis.woah.org/#/in-review/6927 ____

#Luxembourg - #Influenza A #H5N1 viruses of high pathogenicity (Inf. with) (non-poultry including wild birds) (2017-) - Immediate notification

{By Andreas Trepte - Own work, CC BY-SA 2.5, https://commons.wikimedia.org/w/index.php?curid=39163967 } Wild Common Cranes. Source: WOAH,  https://wahis.woah.org/#/in-review/6918 ____

Terracotta Head of a Man, Ancient Greek Painting and Sculpture (ca. 600 BC)

 Public Domain. Source: WikiArt,  https://www.wikiart.org/en/ancient-greek-painting/terracotta-head-of-a-man--600 ____

History of Mass Transportation: The FS RAL60 Metric Gauge Autorail

  Di Smiley.toerist - Opera propria, CC BY-SA 3.0,  https://commons.wikimedia.org/w/index.php?curid=7690411 Source: Wikipedia,  https://it.wikipedia.org/wiki/Automotrice_FS_RALn_60 ____

History of Mass Transportation: The Henschel Steam Locomotive No. 2000

  By Henschel & Sohn Cassel - https://orka.bibliothek.uni-kassel.de/viewer/fullscreen/02008090546707/1/ , Public Domain,  https://commons.wikimedia.org/w/index.php?curid=164392169 Source: Wikipedia,  https://en.wikipedia.org/wiki/Henschel_%26_Son ____

#Coronavirus Disease Research #References (by AMEDEO, October 25 '25)

  Br J Anaesth THOMAS C, Pearse RM Socioeconomic deprivation and health inequity: independently associated with postoperative outcomes, and does this matter? Br J Anaesth. 2025;135:1141-1143. PubMed           Abstract available Clin Infect Dis TARTOF SY, Aliabadi N, Goodwin G, Slezak J, et al Estimated Vaccine Effectiveness for Respiratory Syncytial Virus-Related Acute Respiratory Illness in Older Adults: Findings From the First Postlicensure Season. Clin Infect Dis. 2025 Oct 21:ciaf496. doi: 10.1093. PubMed           Abstract available MANABE YC, Hamill MM, Palamountain KM, Achenbach CJ, et al The Critical Importance of Clinical Use Case to Inform Point-of-Care Technology Development: A Case Study of Human Immunodeficiency Virus Nucleic Acid Assays in the United States. Clin Infect Dis. 2025 Oct 23:ciaf510. doi: 10.1093. PubMed           Abstract available Graefe...

#Influenza and Other Respiratory Viruses Research #References (by AMEDEO, October 25 '25)

  Antiviral Res BESSONNE M, Morel J, Nevers Q, Groutsch J, et al Inhibition of influenza virus replication by artificial proteins (alphaReps) targeting its RNA-polymerase. Antiviral Res. 2025 Oct 21:106300. doi: 10.1016/j.antiviral.2025.106300. PubMed           Abstract available BMC Pediatr WONG K, Ducharme R, Murphy MSQ, Clarke AE, et al SARS-CoV-2 infection in pregnancy and infant outcomes in the first year of life: a retrospective cohort study. BMC Pediatr. 2025;25:842. PubMed           Abstract available MAGGIO ABR, Palomo S, Joye R, Huguet H, et al Reduced aerobic capacity in children with multisystem inflammatory syndrome in children (MIS-C) after PICU admission: a retrospective cohort study, 2020-2022. BMC Pediatr. 2025;25:835. PubMed           Abstract available Cell HICKMAN HD, Moutsopoulos NM Don't forget to floss! An innovative approach for vaccine del...

Joint #FAO / #WHO / #WOAH Rapid #Risk #Assessment of Rift Valley fever (#RVF) in #Senegal and #Mauritania: Implications for Public Health and Animal Health (Oct. 24 '25)

  {Excerpt} Risk statement This risk assessment is based on the current epidemiological and epizootic situation of Rift Valley fever (RVF) in Senegal and Mauritania , from 20 September through 8 October 2025. The risk assessment was conducted separately for each country . However, the findings indicate that the level of risk is the same for both countries across all levels, for both human and animal health .   During this period , Senegal reported 119 confirmed human RVF cases , including 16 deaths , resulting in a case fatality rate (CFR) of 13.4% . Cases were recorded across eight health districts in three regions of Senegal, with the majority in Saint-Louis Region with 110 cases (92%) followed by Louga (four cases) and Matam (one case).  The affected districts in Saint-Louis Region : Podor, Richard-Toll, Dagana, and Saint-Louis are located along the northern border with Mauritania along the Senegal River.   The most affected age groups were 15- 35 years ...

#Assessment of #malnutrition in preschool-aged #children by mid-upper arm circumference in the #Gaza Strip (January, 2024–August, 2025): a longitudinal, cross-sectional, surveillance study

  Summary Background Since October, 2023, Palestinian children in the Gaza Strip have suffered war-induced displacement, food insecurity, malnutrition, and elevated risks of famine and mortality . In this study, we aimed to document the extent of, and patterns in, wasting malnutrition in children aged 6–59 months across the Gaza Strip between January, 2024, and August, 2025. Methods This longitudinal, cross-sectional, surveillance study was conducted across a total of 16 UN Relief and Works Agency for Palestine Refugees in the Near East health centres and 78 medical points established within school shelters and tent encampments across the five governorates of Gaza. Children aged 6–59 months were screened for wasting malnutrition by mid-upper arm circumference (MUAC) measurement. Children with a MUAC of less than 125 mm were enrolled into therapeutic feeding regimens. MUAC Z scores were derived from published WHO age-specific and sex-specific arm circumferential growth curves. Month...

Detection of #WNV, #USUV and #Insect-Specific #Bunyaviruses in #Culex spp. Mosquitoes, #Greece, 2024

  Abstract Greece is one of the countries in Europe most affected by West Nile virus (WNV), and since 2010, when the virus caused a large outbreak with 197 human neuroinvasive cases , outbreaks occur almost every year. Mosquito surveillance is an indirect sign of virus circulation; therefore, the purpose of the study was the molecular detection of WNV in 45,988 C. pipiens s.l. mosquitoes collected during 2024 in four Regions of Greece and the genetic characterization of the virus strains. WNV was detected in 41 of 1316 ( 3.12% ) Culex spp. mosquito pools . Next-generation sequencing was applied to the WNV-positive samples that had a high viral load . All WNV sequences belong to Cluster B of the sub-lineage Europe WNV-2A presenting a temporal clustering. The WNV infection rates varied highly across the Regions, regional units and months, being higher in Thessaly and Central Macedonia Regions , especially in July and September. All mosquito pools were also tested for Usutu virus (USU...

#UK - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

  {England} Premises of 32,000 free range laying hens. Samples taken were positive for HPAI H5N1. Birds presented clinical signs prior to testing. Source: WOAH,  https://wahis.woah.org/#/in-review/6914 ____

#Resurgence of Zoonotic Highly Pathogenic Avian #Influenza #H5N1 Virus in #Cambodia

  {Excerpts} To the Editor : After a decade of no reported human cases, Cambodia faces a resurgence of highly pathogenic avian influenza (HPAI) A(H5N1) virus infections , with an overall mortality of 38%. Cases have occurred primarily in children and adolescents who were exposed to infected poultry (...). From February 2023 through August 2024, a total of 16 infections were detected through the long-standing national influenza-like illness and severe acute respiratory infection surveillance systems, both of which were strengthened by expanded laboratory-testing capacity that was developed during the coronavirus disease 2019 pandemic. All 16 patients reported exposure to sick or dead poultry , and outbreak investigations identified contemporary, genetically similar viruses in poultry collected in or around case households or from active, longitudinal surveillance of live-bird markets . Genomic sequencing revealed an avian origin for all the human infections , and sequences have been...

Development of a cross-protective common #cold #coronavirus #vaccine

  ABSTRACT Common cold coronaviruses, such as OC43 and HKU1, typically cause mild respiratory infections in healthy people. However, they can lead to severe illness in high-risk groups , including immunocompromised individuals and older adults. Currently, there is no clinically approved vaccine to prevent infection by common cold coronaviruses. Here, we developed an mRNA vaccine expressing a stabilized spike protein derived from OC43 coronavirus and tested its efficacy in different challenge models in C57BL/6 mice . This novel OC43 vaccine elicited OC43-specific immune responses, as well as cross-reactive immune response against other embecoviruses , including HKU1 and mouse hepatitis virus (MHV-A59). Interestingly, this OC43 vaccine protected mice not only against a lethal OC43 infection but also against a distant embecovirus, MHV-A59. These findings provide insights for the development of common cold coronavirus vaccines, demonstrating their potential to protect against various c...

#Clinical Characteristics of #Paediatric #RSV, #Influenza, and #SARS-CoV-2 Infections: Insights from Three Consecutive Seasons

  Abstract Background :  The purpose of this study was to retrospectively analyse the clinical presentation of RSV, Influenza , and SARS-CoV-2 infections in children across three consecutive seasons (2022/2023; 2023/2024; and 2024/2025).  Methods :  Of the 321 hospitalised patients , 129 ( 36% ) tested positive for RSV , 110 ( 38% ) for Influenza , and 82 ( 26% ) for SARS-CoV-2 . Children were aged ≤ 17 years (median: 15 months). The data were statistically analysed using the χ2 test, multinomial multivariable logistic regression, OR (odds ratio), and 95% CI (confidence interval).  Results :  Significant independent predictors of RSV infection were auscultatory abnormalities (OR: 15.9 [1.49–169]) and hospital admission ≥ 4 days after symptom onset (OR: 32.5 [1.19–907]). Among RSV-positive patients , compared with those aged < 6 months , those aged 7–24 months were more likely to present with higher CRP levels (OR 1.06 [1.003–1.13]), reduced appetite (OR ...

#Belgium - High pathogenicity avian #influenza #H5N1 viruses (#poultry) (Inf. with) - Immediate notification

  {Di Riki7 - Opera propria, Pubblico dominio, https://commons.wikimedia.org/w/index.php?curid=6957499 } A farm with Meleagris gallopavo species birds in Vlaanderen Region.  Source: WOAH,  https://wahis.woah.org/#/in-review/6921 ____